CAS: 107263-95-6; 1-Fluoropyridiniumtriflate

相似化合物

52193-54-1 130433-68-0 107264-00-6

上下游产品

CAS号110-86-1 吡啶 | CAS号1493-13-6 三氟甲烷磺酸 | CAS号84355-13-5 N-Trimethylsily... | CAS号88188-06-1 TMSOTf | CAS号2926-29-6 三氟代甲烷亚磺酸钠 | CAS号33454-82-9 三氟甲磺酸锂 | CAS号2926-30-9 三氟甲磺酸钠 | CAS号65007-00-3 三氟甲基磺酸-2-吡啶基酯 | CAS号372-48-5 2-氟吡啶 | CAS号111399-94-1 Pyridine,2-[(1-... | CAS号111399-93-0 2-((2-fluoropro... | CAS号1008-89-5 2-苯基吡啶 | CAS号142-08-5 2-羟基吡啶 | CAS号1628-89-3 2-甲氧基吡啶 | CAS号109-09-1 2-氯吡啶 | CAS号36075-06-6 2-二乙氨基吡啶 | CAS号109-04-6 2-溴吡啶

N-Trimethylsilylpiridinium Triflate置于fluorine体系中,用 乙腈 用作溶剂,以78%的收率获得三氟甲磺酸n-吡啶鎓
参考文献:N-Fluoropyridinium Triflate And Its Analogs,The First Stable 1:1 Salts Of Pyridine Nucleus And Halogen Atom
标题:N-Fluoropyridinium Triflate And Its Analogs,The First Stable 1:1 Salts Of Pyridine Nucleus And Halogen Atom
摘要:
Doi:10.1016/s0040-4039(00)84772-3

专利信息

专利号:US-2023287032-A1
优先权日:2020-08-14
标 题:Synthesis of fluorinated nucleotides
发明人：CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO
权利人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO; MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2′-(S)-fluoro-thio-adenosine monophosphate or 2′-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

专利号:US-2023174567-A1
优先权日:2020-05-22
标题:Synthesis of fluorinated nucleotides
发明人：ARMIGER TRAVIS; BELYK KEVIN M; BENKOVICS TAMAS; CHUNG CHEOL K; JI CHEN YINING; JOHNSON HEATHER CLAIRE; KLAPARS ARTIS; LIU ZHIJIAN; LIU ZHUQING; MOORE JEFFREY C; NEEL ANDREW J; PENG FENG; RUMMELT STEPHAN M; SALEHI MARZUARANI NASTARAN; SHERRY BENJAMIN D; SONG ZHIGUO JAKE; TURNBULL BEN WILLIAM HULME; WANG LU; XU FENG
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (2S,3R,4S,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-fluoro-4-hydroxy-2-(mercaptomethyl)tetrahydrofuran-3-yl dihydrogen phosphate, also known as 3′-fluoro-thio-guanosine monophosphate or 3′-F-thio-GMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation. (I)

专利号:US-12234203-B2
优先权日:2020-03-12
标 题:Process for the synthesis of cannabidiol and intermediates thereof
发明人：ANAND RADHIKA; SHARMA SUMIT; SINGH CHAM PANKAJ; GANNEDI VEERANJANEYULU; KUMAR MUKESH; PRATAP SINGH VARUN; PRAKASH RAHUL VISHAV; ASREY VISHWAKARMA RAM; PAL SINGH PARVINDER
权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF T; COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S
摘要:The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

专利号:US-7807837-B2
优先权日:2004-05-07
标 题 :Scalable synthesis of imidazole derivatives
发明人：JONES TODD K; MANI NEELAKANDHA
权利人:JANSSEN PHARMACEUTICA NV
摘要:Imidazole derivatives, compositions containing them, methods of preparing them, including regioselective scale-up synthetic methods, and methods of using them.

专利号:US-2022340507-A1
优先权日:2020-03-12
标题:Process for the synthesis of cannabidiol and intermediates thereof

专利号:US-7507756-B2
优先权日:2004-05-07
标 题 :Scalable synthesis of imidazole derivatives