CAS: 6285-05-8; 4'-Chloropropiophenone

上下游产品

propionaldehyde oxime 4-chlorophenyldiazonium salt 1-(p-chlorophenyl)-1-methoxyethene propionyl chloride 1-(4-chlorophenyl)-1-(2-pyridyl)-1-propanol 1-(4-chloro-phenyl)-2-methyl-3-pyrrolidino-propan-1-one 1-(4-chloro-phenyl)-2-methyl-3-piperidino-propan-1-one para-chlorobenzoic acid

1-烯丙基-4-氯苯置于叔丁基过氧化氢,Palladium Diacetate,对甲苯磺酸体系中,用 水,乙腈 作为反应溶剂,化学反应 6.0H,以98%的收率获得产物4-氯苯丙酮
参考文献:Direct Conversion Of Allyl Arenes To Aryl Ethylketones Via A Tbhp-Mediated Palladium-Catalyzed Tandem Isomerization-wacker Oxidation Of Terminal Alkenes
标题:Direct Conversion Of Allyl Arenes To Aryl Ethylketones Via A Tbhp-Mediated Palladium-Catalyzed Tandem Isomerization-wacker Oxidation Of Terminal Alkenes
摘要:通过tbhp介导的钯催化串联异构化-Wacker氧化反应,成功开发了对末端烯烃的反应.
DOI:10.1039/c5Ob00586H

专利信息

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:EP-0946478-B1
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehydes, ketones and hydroxamic acid compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to processes for the solid-phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-9409879-B2
优先权日:2011-03-29
标 题 :Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
发明人：DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA
权利人:DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA; CENTRE NAT RECH SCIENT
摘要:Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents.

专利号:US-3772366-A
优先权日:1964-09-29
标 题 :Process for the preparation of 9beta,10beta steroids
发明人：USKOKOVIC M; WILLIAMS T
权利人:HOFFMANN LA ROCHE
摘要:THE PRESENT INVENTION IS DIRECTED TO A PROCESS FOR THE COMPLETE CHEMICAL SYNTHESIS OF STEROIDS HAVING THE 9B, 10A-CONFIGURATION FROM THE NATURAL STERIOIDS POSSESSING THE 9A, 10B-CONFIGURATION INCLUDING INTERMEDIATES IN THIS SYNTHESIS. THE STEROIDS WITH THE 9B,10A-CONFIGURATION ARE USEFUL AS ANABOLIC AGENTS, ANTI-ANDROGENIC AGENTS, PROGESTATIONAL AGENTS AND AS SALT-RETAINING AGENTS.

专利号:WO-2023086801-A1
优先权日:2021-11-09
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.