CAS: 621-61-4; 1,3-Dihydroxypropan-2-Yl Stearate

该化合物是一种谷状酸酯酯,被归类为单丙烯酸,在室温下是白色到白色的蜡状固体,在室内温度下可溶解于乙醇和氯仿等有机溶剂,但在水中只有略微溶解.该化合物通常用作乳化剂,稳定剂和食品,化妆品和药品中的厚剂,因为其能够改进质素和增强乳胶稳定性.2-Monostearin展示表面活性特性,使其能减少不同阶段之间的表面紧张,这对于需要统一分布成分的配方特别有用.此外,该物质具有潜在的健康利益,包括其在脂质新陈代谢中的作用.一般认为该物质在各种应用中是安全的,尽管必须遵守有关其浓度和用途的管制准则.

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上下游产品

CAS号111425-86-6 [(4S)-2,2-dimet... | CAS号57-11-4 硬脂酸 | CAS号10567-18-7 (+/-)-2,2-dimet... | CAS号14811-92-8 (R)-十八烷酸-2,3-二羟丙酯 | CAS号22610-63-5 Stearin

合成工艺路线路线简述

    📜(R)-十八烷酸-2,3-二羟丙酯置于水,对甲苯磺酸,溶剂黄146体系中,化学反应 8.0H,反应生成 2-十八烷酸单甘油酯
    参考文献:光学活性单酰基甘油:合成和纯度评估
    标题:光学活性单酰基甘油:合成和纯度评估
    摘要:尽管结构简单,但 1(或 3)-酰基-Sn-甘油的合成仍然是一个不容忽视的挑战,因为酰基迁移容易,这不仅使合成复杂化,而且使直接 Gc 或 HPLC 分析不可行.迄今为止,单酰基甘油光学纯度的评估几乎完全依赖于比旋光度数据,这些数据价值小,因此对杂质不敏感.现在,已经找到了一种"放大"小比旋光度的简单方法,以及测量 1,2-和 1,3-酰基迁移的实用方法,这些方法为 Mori 的 NMR 分析提供了一种方便且直接的替代方法.莫舍酯.借助这些方法,在合成两种天然单酰基甘油的过程中,研究了一系列脱丙酮的条件.
    DOI:10.1002/ejoc.201300247

    海关参考信息

    专利信息


    专利号:WO-2024130393-A1
    优先权日:2022-12-21
    标 题 :Nanoparticle and method of synthesis thereof
    发明人:MOSKOVCHENKO SVITLANA
    权利人:MOSKOVCHENKO SVITLANA
    摘要:The present technology relates to nanoparticles, compositions comprising said nanoparticles, and methods of synthesis of said nanoparticles; wherein the nanoparticles comprise a metal nanoparticle core, a first coating of amphiphilic molecules, and a second coating of essential oil, essential oil primary constituent, or both, which combine the antimicrobial properties of metal nanoparticles, amphiphilic molecules, and essential oil or essential oil primary constituents.

    专利号:EP-1779900-B1
    优先权日:2005-10-29
    标 题 :Cosmetic or dermatological composition for prevention of light-induced aging
    发明人:NEUFANG HARTMUT; TILL MARTINA
    权利人:APOTHEKER WALTER BOUHON GMBH
    摘要:Use of a composition (I) comprising vitamin A (0.02-0.09 wt.%), phytosterol (0.1-3 wt.%), vitamin E (0.5-3 wt.%) and their biochemical precursors or derivatives, for the production of cosmetic or dermatological preparation for the inhibition of a light-induced gene expression of the synthesis of a collagenase in the skin. An independent claim is included for the cosmetic or dermatological preparation comprising (I), urea (1-4 wt.%), caprylic/capric acid triglyceride (caprylic/capric triglyceride according to INCI standard), lipids, consistency agents, emulsifying agents, polymers, perfumes, preservatives and water. ACTIVITY : Dermatological. MECHANISM OF ACTION : Gene expression of synthesis of collagenase Inhibitor.

    专利号:WO-9713503-A1
    优先权日:1995-10-13
    标 题:Synthesis of drug nanoparticles by spray drying
    发明人:SELVARAJ ULAGARAJ; MESSING GARY L
    权利人:PENN STATE RES FOUND; SELVARAJ ULAGARAJ; MESSING GARY L
    摘要:The present invention relates to a method for synthesizing nanoparticles comprising combining an agent and a matrix to form a composite mixture, and spray drying the composite mixture, wherein the nanoparticles are less than about 5000 nm. Suitable agents that can be formulated into nanoparticle in the context of the present invention include therapeutic and diagnostic agents, cosmetic, dye, photographic, food, pesticide agents, among others.

    专利号:US-2024050916-A1
    优先权日:2020-12-14
    标题:Biodegradable microcapsules based on composite material and synthesis process
    发明人:VRHUNEC ALJOSA; STEFANEC DEJAN; KOTNIK TOMAZ; KRANJC DOMEN
    权利人:MIKROCAPS D O O
    摘要:The present invention relates to biodegradable microcapsules with a membrane formed of a biodegradable composite material and their synthesis. Biodegradable microcapsules obtained as described in the present invention consist of a core material comprising at least one liquid water-immiscible active component, and a membrane that encloses this core material, the membrane consisting of a composite material comprising a carrier polymer framework and at least one filler deposited into the pores of said carrier polymer framework and deposited onto the surface of said carrier polymer framework, wherein the carrier polymer framework is made of at least one polymer and the filler is a lipophilic biodegradable organic compound which is solid at room temperature and has a melting point above 40° C. The thickness of the membrane is between 20 and 200 nm and the microcapsule diameter is between 1 and 50 pm. Biodegradable microcapsules as described in the present invention are used in the form of aqueous dispersions as additives to fabric softeners, detergents, pesticides, pharmaceutical ingredients, paints, cosmetics products and the like.

    专利号:US-2025222420-A1
    优先权日:2022-03-15
    标题:Biodegradable microcapsules based on crystalline materials and synthesis process
    发明人:STEFANEC DEJAN; VRHUNEC ALJOSA; KRANJC DOMEN
    权利人:MIKROCAPS D O O
    摘要:The present invention relates to a water dispersion of biodegradable microcapsules, with a membrane formed of a biodegradable crystalline material only, i.e. free of polymer framework, and synthesis thereof. Biodegradable microcapsules consist of a core material comprising at least one water-immiscible and water-insoluble active component, and a membrane that encloses this core material, the membrane consisting of a highly crystalline material only, wherein the crystalline material is a lipophilic biodegradable organic compound which is solid at room temperature and has a melting point equal to or above 40° C. Biodegradable microcapsules are in the form of aqueous dispersions and are used primarily for encapsulation of pesticides for use in pest control applications.

    专利号:US-2007010581-A1
    优先权日:2002-11-29
    标 题 :Use of 2,5-dihydroxybenzenesulfonic compounds for the treatment of disorders based on an impairment of no production and/or of regulation of edhf function
    发明人:ESTEVE-SOLER JOSE; SAENZ DE TEJADA-GORMAN INIGO; ANGULO-FRUTOS JAVIER
    权利人:ESTEVE-SOLER JOSE; SAENZ DE TEJADA-GORMAN INIGO; ANGULO-FRUTOS JAVIER
    摘要:The present invention relates to the use of 2,5-dihydroxybenzenesulfonic compounds for the manufacture of medicament for the regulation of nitric oxide (NO) synthesis and/or the regulation of EDHF (Endothelium-derived-Hyperpolarizing-Factor) in the endothelium of humans or animals, whereby the medicament is administered in a daily dose of the 2,5-dihydroxybenzenesulfonic compounds of formula I of <500 mg.

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    合成参考文献


    参考文献:10.1186/gm115
    摘要:Roberts LD, Hassall DG, Winegar DA, Haselden JN, Nicholls AW, Griffin JL. Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse. Genome Med. 2009 Dec 07;1(12):115.
    参考文献:10.1096/fasebj.11.1.9034165
    摘要:Ghosh S, Strum JC, Bell RM. Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling. FASEB J. 1997 Jan;11(1):45–50. doi: 10.1096/fasebj.11.1.9034165.
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