CAS: 541-47-9; 3-Methylbut-2-Enoic Acid

相似化合物

556-82-1 924-50-5 638-10-8

上下游产品

CAS号556-82-1 3-甲基-2-丁烯-1-醇 | CAS号3017-69-4 1-溴-2-甲基丙烯 | CAS号201230-82-2 carbon monoxide | CAS号141-79-7 异丙叉丙酮 | CAS号34450-60-7 2-Butenoic acid... | CAS号75-16-1 甲基溴化镁 | CAS号625-08-1 β-羟基异戊酸 | CAS号638-10-8 3,3-二甲基丙烯酸乙酯 | CAS号124-38-9 二氧化碳 | CAS号111190-17-1 3-methyl-3-thio... | CAS号10035-29-7 (2Z,4Z,6Z,8Z)-4... | CAS号111424-46-5 3-(4-methoxyphe... | CAS号10606-43-6 3-methylbut-2-e... | CAS号100883-69-0 2,2-dimethyl-7-... | CAS号109892-46-8 SEC-BUTYL 3-MET... | CAS号4394-72-3 4-methyl-6-(2-m... | CAS号3350-78-5 3,3-二甲基丙烯酰氯 | CAS号43163-94-6 3-氟-DL-缬氨酸 | CAS号78-59-1 异佛尔酮

β-羟基异戊酸置于硫酸体系中,化学反应生成 3,3-二甲基丙烯酸
参考文献:Neubauer,Justus Liebigs Annalen Der Chemie,1858,Vol. 106,P. 67
标题:Neubauer,Justus Liebigs Annalen Der Chemie,1858,Vol. 106,P. 67

专利信息

专利号:WO-2012017400-A1
优先权日:2010-08-03
标 题 :Synthesis of acyl-pantetheine derivatives and the use thereof in the synthesis of acyl-coenzyme a derivatives
发明人：VAN DIJK ALBERDINA AIKE; BADENHORST CHRISTOFFEL PETRUS STEPHANUS
权利人:UNIV NORTHWEST; VAN DIJK ALBERDINA AIKE; BADENHORST CHRISTOFFEL PETRUS STEPHANUS
摘要:The present invention relates to a novel synthesis method for acyl-pantetheine derivatives. The present invention further relates to the use of said synthesized acyl-pantetheine derivatives as a starting material in the enzymatic synthesis of acyl-coenzyme A derivatives. According to a first aspect thereof, the present invention provides a method for the synthesis of acyl-pantetheine derivatives, the method including the steps of: a) providing a source of pantetheine; b) providing a source of acyl ester; and c) contacting the source of pantetheine with the source of acyl ester to form the corresponding acyl-pantetheine derivative, having the general formula (I), wherein R is an acyl group.The present invention also provides a method for the synthesis of acyl-coenzyme A derivatives as well as the use of a source of pantetheine and a source of acyl ester in the preparation steps of these two methods.

专利号:US-9376461-B2
优先权日:2011-06-06
标 题:Non-enzymatic synthesis of O-acetyl-ADP-ribose and analogues thereof
发明人：KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B
权利人:KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B; GLAXOSMITHKLINE LLC
摘要:Provided herein is a simple, one-step, non-enzymatic synthesis of O-Acetyl-ADP-ribose (OAADPR) from NAD and sodium acetate in acetic acid. The extension of this reaction to other carboxylic acids, demonstrates that the reaction between NAD, and NAD analogs produces mixtures of the corresponding 2′- and 3′-carboxylic esters. Included are O-carboxyl-ADP-ribose compounds and corresponding methods of synthesis (e.g., O-propionyl-ADP-ribose, O-succinyl-ADP-ribose, O-malonyl-ADP-ribose), as well as non-adenosine nucleoside compounds.

专利号:US-11046978-B2
优先权日:2016-03-16
标 题:Synthesis of isoprenoids and derivatives
发明人：GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:UNIV RICE WILLIAM M
摘要:This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds. These condensation reactions serve as a platform for the synthesis of isoprenoid precursors when utilized in combination with a variety of metabolic pathways and enzymes for carbon rearrangement and the addition/removal of functional groups. Isoprenoid alcohols are key intermediary products for the production of isoprenoid precursors in these novel synthetic metabolic pathways.

专利号:US-4219489-A
优先权日:1978-09-05
标题:Synthesis of steroids
发明人：BUNES LEONARD A; JOHNSON WILLIAM S
权利人:STANFORD LELAND JUNIOR UNIV TR
摘要:Method and compounds are provided for use in the synthesis of steroids wherein a polyolefin is provided having an initiating group having a chalcogen atom in juxtaposition to a double bond, so as to be capable of bond formation to close to form a ring and having a terminating group involving pi unsaturation (a double or triple bond) conjugated to an aromatic ring. Upon acid catalysis, sigma bonds are formed through the interaction of a carbocation formed at the carbon atom bonded to the chalcogen atom and the double bond intermediate the initiating group and the terminating group, which close to form rings of a steroid nucleus, the carbocation interacting with the pi unsaturation conjugated with the aromatic group and being captured by a nucleophile present in the acidic reaction medium. The resulting steroid product may then be modified in known ways to produce known steroids.

专利号:US-5191110-A
优先权日:1987-05-21
标题 :Process for the synthesis of vitamin A and certain ones of derivatives
发明人：SOLLADIE GUY; FORESTIER SERGE; LANG GERARD
权利人:OREAL
摘要:According to this process, one effects a stereospecific reduction of the two hydroxyl groups of an ether-diol by a mixture (titanium trichloride, lithium aluminum hydride) at a temperature between 5° C. and about 40° C. and that optionally, one converts the resulting ether into vitamin A, retinol or retinoic acid. n Application to the synthesis of all-trans compounds selected from the group consisting of vitamin A and its ethers, retinol and retinoic acid, and their 13-cis isomers.

专利号:US-4064150-A
优先权日:1976-05-26
标 题 :Synthesis of isoprenoid 1,5-dienes
发明人：KATZENELLENBOGEN JOHN A
权利人:UNIV ILLINOIS
摘要:Aliphatic acids containing an isoprenoid 1,5-diene moiety are prepared in high yields by the selective gamma alkylation of α,β-unsaturated acids with allylic electrophiles. The gamma-regioselectivity of the alkylation is controlled by the use of the dicopper(I) dienolates prepared from the α,β-unsaturated acids. The method offers a particularly facile means for synthesizing isoprenoid 1,5-diene natural products such as farnesoic acid by alkylation of senecioic acid with geranyl bromide; geranoic acid by alkylation of senecioic acid with 3,3-dimethallyl bromide; and dl-lanceol by alkylation of tiglic acid with an allylic bromide derived from dl-limonene. Such products find use in the synthesis of insect pheremones, insect juvenile hormones, and components of perfumes.