CAS: 49584-26-1; 4-Cyanobenzenesulfonyl Chloride

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CAS号138-41-0 卡西尼特 | CAS号873-74-5 对氨基苯腈 | CAS号3058-39-7 4-碘苯甲腈 | CAS号98555-79-4 4-(trichloropho... | CAS号10026-13-8 五氯化磷 | CAS号227935-30-0 4-(1-哌啶基磺酰基)苯甲腈 | CAS号205259-71-8 4-(1-哌啶基磺酰基)苯甲胺 | CAS号3119-02-6 对氰基苯磺酰胺 | CAS号166335-18-8 PNU-103017 | CAS号165668-32-6 N-(3-chloro-1H-... | CAS号650628-69-6 4-cyano-N-[2-(d... | CAS号74670-75-0 4-cyano-N-ethyl... | CAS号838-33-5 4-苯并噁唑-2-苯甲腈 | CAS号852399-79-2 4-(4-磺酰基吗啉)-苄胺盐酸盐 | CAS号94341-56-7 4-苯磺酰基苄胺

对羧基苯磺酰胺置于五氯化磷,氮体系中,化学反应 18.0H,反应生成 4-氰基苯磺酰氯
参考文献: Photoinitiators Having Triarylsulfonium And Arylsulfinate Ions[fr] Photo-Initiateur Possedant Des Ions Triarylsulfonium Et Arylsulfinate
标题: Photoinitiators Having Triarylsulfonium And Arylsulfinate Ions[fr] Photo-Initiateur Possedant Des Ions Triarylsulfonium Et Arylsulfinate
摘要:提供了包括用于自由基聚合反应的光引发剂体系的组合物.更具体地,光引发剂包括芳基亚磺酸盐离子和三芳基砜离子.还提供了包括光引发剂的光聚合组合物的聚合方法.此外,还披露了三芳基砜芳基亚磺酸盐.

专利信息

专利号:US-9969685-B2
优先权日:2016-09-28
标 题 :Enantioselective synthesis of pyrroloindole compounds
发明人：SCHMIDT MICHAEL ANTHONY
权利人:BRISTOL MYERS SQUIBB CO
摘要:Compounds according to formula (I) or (II), wherein R 1 , R 2 , and R 3 are as defined in the specification, are versatile intermediates for the synthesis of DNA minor groove binder-alkylators having a cyclopropapyrroloindole (CPI) or seco-CPI alkylating subunit.

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:US-6943254-B2
优先权日:1997-03-07
标 题 :Synthesis of pyrazinyl pyridine-3-sulfonamide compounds
发明人：HOGAN PHILIP JOHN
权利人:ASTRAZENECA UK LTD
摘要:A process for the manufacture of: n n nwherein R is (1-4C)alkyl, carboxyl(1-4C)alkyl or 1,3,4-oxadiazol-2-yl comprises:n (a) reaction of the diazonium salt of 3-amino-2-chloropyridine with thionyl chloride in water and an electron transfer catalyst; (b) reaction with isobutyl-(3-methoxy-5-methylpyrazin-2-yl)carbamate and an alkali metal hydride in inert solvent; and (I) where R is (1-4C)alkyl, carboxy(1-4C)alkyl: (c) reaction with a boronic acid: n n (or an anhydride or ester therof) in the presence of a base and a palladium or nickel catalyst in solvent; and removal of the isobutoxy carbonyl group; or (ii) where R is 1,3,4-oxadiazol-2-yl (c) reaction with 4-methoxycarbonylphenylboronic acid (or an anhydride or ester thereof) with a source fluoride ion under aqueous conditions; (d) removal of the isobutoxycarbonyl protecting group; (e) conversion of the methyl ester group to the hydrazide; and (f) conversion to a 1,3,4-oxadiazol-2-yl moiety.

专利号:US-12336981-B2
优先权日:2010-09-03
标题 :Compounds and compositions for the inhibition of NAMPT
发明人：BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; DRAGOVICH Peter; GOSSELIN FRANCIS; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; ROTH BRUCE; SMITH CHASE C; WANG ZHONGGUO; YUEN PO-WAI; ZHENG XIAOZHANG
权利人:VALO HEALTH INC; GENENTECH INC
摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

专利号:WO-2018064094-A1
优先权日:2016-09-28
标题:Enantioselective synthesis of pyrroloindole compounds

专利号:CN-109020924-A
优先权日:2018-10-24
标 题 :A kind of method of benzenesulfonyl chloride compound and secondary amine metal-free catalyzed synthesis of benzenesulfonamide compound