CAS: 38385-95-4; 2-(Piperidin-4-yl)-1H-Benzo[d]Imidazole

相似化合物

953071-73-3 824403-74-9 38385-95-4

上下游产品

CAS号110963-63-8 1-(2-乙氧基-乙基)-2-... | CAS号953071-73-3 4-(1H-苯并[D]咪唑-2...

邻苯二胺置于氢氧化钾,Ppa体系中,用530 Mg (27%)的收率获得2-(4-哌啶)-1H-苯并咪唑
参考文献:Method For Treating Allergies Using Substituted Pyrazoles
标题:Method For Treating Allergies Using Substituted Pyrazoles
摘要:使用取代吡唑烷治疗过敏症状的方法,包括特应性过敏症状.

专利信息

专利号:US-11370742-B2
优先权日:2018-07-24
标 题 :Process and intermediates for the preparation of bilastine
发明人：HERNÃ?NDEZ HERRERO GONZALO; GARCÃ?A DOMÃ?NGUEZ NEFTALÃ?; MORÃ?N POLADURA PABLO; GONZÃ?LEZ GARCÃ?A TANIA; GANZA GONZÃ?LEZ Ã?LVARO; TATO CERDEIRAS PALOMA
权利人:FAES FARMA SA
摘要:The invention relates to a process for preparing a compound of (III) n n n n n n n n n n n n whereinn X is a leaving group; and R 1 is C 1 -C 6 alkyl;n nwhich comprises oxidative rearrangement of a compound of formula (II) or a solvate thereofn n n n n n n n n n n n n n n n Compounds of formula (III) are key intermediates in the synthesis of Bilastine.

专利号:US-10106522-B2
优先权日:2014-12-29
标题:Benzimidazole derivatives as antihistamine agents
发明人：RODES SOLANES ROSA; OLIVERA TIZNE ROBERTO; HERNÃ?NDEZ HERRERO GONZALO; RUBIO ROYO VÃ?CTOR; LEDO GÓMEZ Francisco
权利人:FAES FARMA SA
摘要:The invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, a method of synthesis of said compounds, pharmaceutical compositions comprising them and their use in the treatment and/or prevention of conditions mediated by H 1 histamine receptor, such as allergic disorders or diseases.

专利号:US-2008139558-A1
优先权日:2006-02-24
标题 :Quinolones useful as inducible nitric oxide synthase inhibitors
发明人：SMITH NICHOLAS D; ROPPE JEFFREY R; BONNEFOUS CELINE; PAYNE JOSEPH E; ZHUANG HUI; CHEN XIAOHONG; LINDSTROM ANDREW K; DURON SERGIO G; HASSIG CHRISTIAN A; NOBLE STEWART A
权利人:KALYPSYS INC
摘要:The present invention relates to novel quinolones of Formula I that inhibit inducible NOS synthase together with methods of synthesizing and using the compounds including methods for inhibiting or modulating nitric oxide synthesis and/or lowering nitric oxide levels in a patient by administering the compounds for the treatment of disease.

专利号:CN-117924240-A
优先权日:2023-12-26
标 题:A synthesis process of tert-butyl 4-(1H-benzo[D]imidazol-2-yl)piperidine-1-carboxylate