1,2,3-三甲氧基苯置于溶剂黄146体系中,用 四氢呋喃,N-甲基乙酰胺,正己烷 用作溶剂,以24%的收率获得2,3,4-三甲氧基苯甲醛 参考文献:Phenol Compound Having Antioxidative Activity And The Process For 标题:Phenol Compound Having Antioxidative Activity And The Process For 摘要:揭示了一种由以下式(1)表示的酚化合物:##str1## 其中r.Sup.0代表h,烷基或烷氧基;R.Sup.1代表烷基;R.Sup.2代表烷基或烷氧基;Or.Sup.3代表oh;R.Sup.4代表h,较低烷基或酰基,上述取代基中的每一个均可被取代;W代表o,S或nr.Sup.7;其中r.Sup.7代表h,烷基,芳基,Oh或烷氧基,式(2)的一个基团:##str2## 代表一个氨基,该氨基可以是单取代或双取代的,或含有n原子的杂环基团,或其药学上可接受的盐,以及其制备方法.
专利号:US-6524446-B2 优先权日:2001-03-27 标 题 :Process for synthesis of a porphyrin compound using a molecular sieve catalyst under microwave irradiation 发明人:KULKARNI SHIVANAND JANARDAN; RAGHAVAN KONDAPURAM VIJAYA; MOTKURI RADHA KISHAN; NAGABANDI SRINIVAS 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides an improved process for synthesis of porphyrin compounds of the general formula 1 n from pyrrole and aromatic aldehyde over zeolite molecular sieve catalysts using microwave heating, (solvent free) to provide an eco-friendly, economical, faster and selective heterogeneous method.
专利号:US-11384367-B2 优先权日:2016-12-22 标题:Synthesis of bioproducts from lignin-derived aromatics by genetically modified microorganisms 发明人:GLADDEN JOHN M; SKERKER JEFFREY M; KEASLING JAY D; KIRBY JAMES; YAEGASHI JUNKO 权利人:UNIV CALIFORNIA; NAT TECH & ENG SOLUTIONS SANDIA LLC; BATTELLE MEMORIAL INSTITUTE FOR MANAGEMENT AND OPERATION OF PACIFIC NORTHWEST NAT LABORATORY; NATIONAL TECH AND ENGINEERING SOLUTIONS OF SANDIA LLC 摘要:The present invention provides for a method of converting a depolymerized lignin aromatic compound into a bioproduct, comprising: (a) providing a composition comprising a depolymerized lignin aromatic compound, optionally a depolymerized cellulose, and optionally a depolymerized hemicellulose, and (b) introducing a genetically modified microorganism to the composition, wherein the genetically modified microorganism is capable of converting the depolymerized lignin aromatic compound into a bioproduct; such that the depolymerized lignin aromatic compound is converted into a bioproduct.
专利号:US-5783577-A 优先权日:1995-09-15 标题 :Synthesis of quinazolinone libraries and derivatives thereof 发明人:HOUGHTEN RICHARD A; OSTRESH JOHN M 权利人:TREGA BIOSCIENCES INC 摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.
专利号:US-5175302-A 优先权日:1987-07-13 标 题 :Nucleophilic fluoroalkylation of aldehydes 发明人:STAHLY G PATRICK 权利人:ETHYL CORP 摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
专利号:WO-9815524-A1 优先权日:1996-10-10 标 题:Improved process for the synthesis of beta-ketonitriles 发明人:DAVIS EDWARD MARK; ELLIS JAMES E 权利人:WARNER LAMBERT CO; DAVIS EDWARD MARK; ELLIS JAMES E 摘要:An improved process for the preparation of β-ketonitrile is described where an α-β-enone hydrocyanated in the presence of a tetraalkylammonium hydroxide and acetone cyanohydrin to the desired product as well as the use of β-ketonitriles in the preparation of hydroxybutenolides.
专利号:EP-0406931-B1 优先权日:1989-06-30 标 题 :New analogues of all-bond retroinverted thymopentin, the method for the synthesis of the same and their employment for the preparation of pharmaceutical compositions 发明人:MARIOTTI SABINA; SISTO ALESSANDRO; NENCIONI LUCIANO; VILLA LUIGI; PESSI ANTONELLO 权利人:SCLAVO SPA 摘要:New thymopentin (TP5) analogues whose bonds in the peptide chain are all retro-inverted are disclosed. Such new compounds have the following general formula (I) wherein R is hydrogen or an acyl radical, and R<1> is a group of the formula -OR<2>, wherein R<2> is a hydrogen atom or a hydrocarbon radical, and the corresponding basic or acid addition salts which are pharmaceutically acceptable. The new compounds have immunostimulating activity.
摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 278. 摘要:Tsubouchi, A., Science of Synthesis Knowledge Updates, (2016) 2, 329. 摘要:Leung, M.-k.; Chou, C.-M.; Luh, T.-Y., Science of Synthesis Knowledge Updates, (2018) 2, 420. 摘要:Tsubouchi, A., Science of Synthesis Knowledge Updates, (2016) 2, 335. 摘要:Claver, C.; Peñafiel, I.; Urrutigoïty, M.; Kalck, P., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 313.