CAS: 18217-00-0; 1-(2-Chloroethyl)-4-Methoxybenzene

上下游产品

2-(4-Methoxyphenyl)ethanol 2-chloroethyl tosylate 4-methoxyphenyl magnesium bromide 2-(p-methoxyphenyl)ethyl toluene-p-sulphonate 4-methoxyphenethyl-dimethylamine 4-Methoxystyrene 1,4-bis(4-methoxyphenyl)butane 4-Methoxyphenethylamine

📜2-(P-Methoxyphenyl)Ethyl Toluene-P-Sulphonate置于四乙基氯化铵体系中,用 乙腈 用作溶剂,化学反应生成2-(4-甲氧苯基)-氯乙烷
参考文献:Sn2 在偶极非质子溶剂中的反应.2-芳乙基氯化物,氯甲基芳基醚和氯甲基芳基硫化物在乙腈中的氯同位素交换反应
标题:Sn2 在偶极非质子溶剂中的反应.2-芳乙基氯化物,氯甲基芳基醚和氯甲基芳基硫化物在乙腈中的氯同位素交换反应
摘要:在偶极非质子溶剂中研究了具有对称过渡态的 Sn2 反应.发现四乙基氯化铵与三类取代甲基氯,2-芳基乙基氯,氯甲基芳基醚和氯甲基芳基硫化物在乙腈中的氯同位素交换反应具有非常好的哈米特相关性.2-芳基乙基氯的反应常数为正,具有α-杂原子的甲基氯的反应常数为负.反应中心 α 位上氧和硫原子的存在导致速率分别提高约 105 倍和 103 倍.讨论了这些 Sn2 反应的过渡态特征.
Doi:10.1246/bcsj.44.3091

专利信息

专利号:BR-PI0711208-A2
优先权日:2006-05-19
标 题 :compounds, intermediates for the synthesis of compounds, process, pharmaceutical composition, use of a compound and uses

专利号:RU-2059636-C1
优先权日:1990-07-19
标题:Oxazolyl-derivatives or their pharmaceutically acceptable additive salt, or their stereochemically isomeric form, a method of their synthesis and pharmaceutical composition showing antiallergic activity

专利号:US-9974779-B2
优先权日:2006-05-19
标 题:Piperidine derivatives as human papilloma virus inhibitors
发明人：BLUMENFELD MARTA; COMPERE DELPHINE; GAUTHIER JEAN-MICHEL
权利人:AVIRAGEN THERAPEUTICS INC; VAXART INC
摘要:The present disclosure is directed to antiviral compounds directed against the papilloma virus, to pharmaceutical compositions containing them, to their preparation method and synthesis intermediates, as well as to their use for treating or preventing an infection by the papilloma virus. The present method thus provides an efficient way of treating patients that have lesions associated with an infection by the papilloma virus.