CAS: 13123-92-7; (2,4-Dichlorophenyl)Hydrazine

相似化合物

5446-18-4 5329-12-4 50709-36-9

上下游产品

CAS号554-00-7 2,4-二氯苯胺 | CAS号5446-18-4 2,4-二氯苯肼盐酸盐 | CAS号27165-13-5 2,4-二氯苯重氮化合物 | CAS号871888-10-7 (2,4-dichloro-p... | CAS号13617-98-6 2,4-dichloroben... | CAS号64-17-5 乙醇 | CAS号7647-01-0 盐酸 | CAS号861363-89-5 N-acetyl-N-(2,4... | CAS号861363-87-3 N-acetyl-N-(2,4... | CAS号541-73-1 间二氯苯 | CAS号7664-41-7 氨 | CAS号554-00-7 2,4-二氯苯胺 | CAS号168273-06-1 利莫纳班 | CAS号162758-35-2 里莫那班羧酸 | CAS号170937-37-8 4-(4-chlorophen... | CAS号158941-22-1 5-(4-氯苯基)-1-(2,... | CAS号878002-12-1 2-(2,4-dichloro... | CAS号58791-79-0 5-氨基-1-(2,4-二氯苯...

📜2,4-二氯苯胺置于盐酸,Sodium Nitrite,Tin(Ll) Chloride体系中,用 水 用作溶剂,化学反应 3.0H,反应生成2,4-二氯苯肼
参考文献:苯并咪唑苯hydr衍生物作为抗真菌病原真菌的合成及生物评价.
标题:苯并咪唑苯hydr衍生物作为抗真菌病原真菌的合成及生物评价.
摘要:合成了一系列苯并咪唑苯基hydr衍生物(6A-6Ai),并通过1 H-NMR,Esi-Ms和元素分析对其进行了表征.通过单晶x射线衍射进一步确认6B的结构为(e)构型.使用菌丝体生长速率法筛选了所有化合物的抗枯萎病菌和稻瘟病菌的抗真菌活性.化合物6F表现出对茄形假单胞菌和米曲霉的显着抑制活性,Ec50值分别为1.20和1.85μg/ Ml.体内试验表明,6F可以有效控制上述两种植物病原体引起的稻瘟病和稻瘟病的发生.
Doi:10.3390/molecules21111574

专利信息

专利号:US-11040938-B2
优先权日:2016-07-27
标 题 :Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts
发明人：MA BING; PAN SHUAI
权利人:SHANGHAI HYBRID—CHEM TECH; SHANGHAI HYBRID CHEM TECH
摘要:The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor without interruption. The total reaction time is no more than 20 min.

专利号:US-2007287734-A1
优先权日:2006-06-09
标 题 :Preparation and utility of substituted pyrazole compounds with cannabinoid receptor activity
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:The present disclosure is directed to modulators of CB-1 type receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of the severity and duration of obesity, metabolic syndrome, dyslipidemia, glucose imbalance, the inability to maintain weight loss, insulin resistance, a cardiovascular disorder, memory loss, drug dependence, a depressive disorder, a panic disorder, an obsessive-compulsive disorder, anxiety, post-traumatic stress syndrome, and any other condition in which it is beneficial to inhibit, inversely agonize or modulate a cannabinoid receptor are described.

专利号:US-6132953-A
优先权日:1996-07-02
标 题 :Combinatorial synthesis on soluble polyvalent supports having a discrete architecture
发明人：CHAPMAN KEVIN T; HUTCHINS STEVEN M; KIM RONALD M; MANNA MAHUA
权利人:MERCK & CO INC
摘要:The present invention is directed to the use of a soluble polyvalent support for the preparation of combinatorial libraries of compounds. The resultant combinatorial libraries are useful in screening for biologically active moieties in the drug discovery process or in developing compounds with desired physical and chemical properties.

专利号:US-8461184-B2
优先权日:2006-05-31
标题 :Sulphur containing pyrazole derivatives as selective cannabinoid CB1 receptor antagonists
发明人：LANGE JOSEPHUS H M; KRUSE CORNELIS G; VLIET VAN BERNARD J
权利人:LANGE JOSEPHUS H M; KRUSE CORNELIS G; VLIET VAN BERNARD J; SOLVAY PHARM BV
摘要:The present invention relates to sulphur containing pyrazole derivatives, and their S-oxidized active metabolites, as selective cannabinoid CB 1 receptor antagonists having a high CB 1 /CB 2 receptor subtype selectivity, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of these pyrazole derivatives, to pharmaceutical compositions comprising one or more of these pyrazole derivatives as active ingredients, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders. The compounds have the general formula (I) n nwherein the symbols have the meanings given in the specification.

专利号:WO-2007138050-A1
优先权日:2006-05-31
标题:Sulphur containing pyrazole derivatives as selective cannabinoid cb1 receptor antagonists
发明人：LANGE JOSEPHUS H M; KRUSE CORNELIS G; VAN VLIET BERNARD J
权利人:SOLVAY PHARM BV; LANGE JOSEPHUS H M; KRUSE CORNELIS G; VAN VLIET BERNARD J
摘要:The present invention relates to sulphur containing pyrazole derivatives, and their S-oxidized active metabolites, as selective cannabinoid CB1 receptor antagonists having a high CB1/CB2 receptor subtype selectivity, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said pyrazole derivatives, to pharmaceutical compositions comprising one or more of these pyrazole derivatives as active ingredients, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.

专利号:US-8044203-B2
优先权日:2002-05-10
标 题 :Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups
发明人：MUJUMDAR RATNAKER B; WEST RICHARD MARTIN
权利人:UNIV CARNEGIE MELLON; GE HEALTHCARE UK LTD
摘要:This invention relates to the functionalized cyanine dyes and more particularly, to the synthesis of chiral 3-substituted 2,3′-dimethyl-3H-indole and its derivatives as intermediates for preparation of cyanine dyes, to methods of preparing these dyes and the dyes so prepared.