CAS: 65295-69-4; 2,6-Difluorophenylisocyanate

上下游产品

oxalyl dichloride 2,6-difluorobenzamide bis(trichloromethyl) carbonate 2,6-difluoroaniline N-(2,6-difluorophenyl)-3-(([(2,6-difluorophenyl)amino]carbonyl)amino)-1H-indazole-1-carboxamide 1-(2,6-difluorophenyl)-3-(4-((4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methoxy)phenyl)urea

📜2,6-二氟苯甲酰胺置于草酰氯体系中,用 甲苯 作为反应溶剂,化学反应 3.0H,反应生成 2,6-二氟异氰酸苯酯
参考文献:吡虫隆及其制备方法
标题:吡虫隆及其制备方法
摘要:本发明涉及一种杀虫剂吡虫隆的合成方法.该方法采用离子液体作为催化剂,以2,3二氯‑5‑三氟甲基吡啶,2‑氯‑5‑氨基苯酚,2,6‑二氟苯甲酰胺和草酰氯作为原料,在温和条件下合成吡虫隆.该方法工艺简单,安全性高,副反应少,反应时间短,收率高.使用该方法得到的吡虫隆的收率大于90%,纯度大于99%.

专利信息

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6906056-B2
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
权利人:LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-2004106598-A1
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting Beta-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2005192269-A1
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2005267150-A1
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2008293785-A1
优先权日:2006-04-11
标 题 :Substituted benzothiazole kinase inhibitors
发明人：CONNOLLY PETER J; EMANUEL STUART L; HUANG SHENLIN; TURCHI IGNATIUS J
权利人:CONNOLLY PETER J; EMANUEL STUART L; HUANG SHENLIN; TURCHI IGNATIUS J
摘要:The present invention is directed to substituted benzothiazole compounds of formula (I): n n n n n n n n n n and forms thereof, their synthesis and use for treating a chronic or acute protein kinase mediated disease, disorder or condition.