CAS: 6402-36-4; Traumaticacid

该化合物是一种自然产生的有机化合物,主要来自某些植物的树脂,特别是松树,被归类为双环化合物,以其独特的结构而著称,其中包括一个与环己烷结合的环球环环环,外酸展示了一系列生物活动,包括抗微生物和抗炎特性,使其对制药和农业应用感兴趣.该化合物通常以白晶状固体的形式出现,在有机溶剂中溶解.其化学再活性特征是存在多种功能组,允许各种化学变异.外酸在植物防御机制中发挥作用,特别是在应对伤害方面,并已就其潜在的治疗用途进行了研究.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

10,12,12,12-tetrachlorododecanoic acid methyl ester (E)-dodec-2-enedioic acid dimethyl ester 3-hydroxydodecanedioic acid malonic acid1,12-dodecandiol dodecanedioic acid dimethyl ester 12-oxododecanoic acid 12-hydroxydodecanoic acid

合成工艺路线路线简述

    📜2E-Dodecene-1,12-Dioic Acid Diethyl Ester置于氢氧化钾体系中,用 乙醇,水 作为反应溶剂,化学反应 2.0H,以91%的收率获得产物反式-2-十二碳烯二酸
    参考文献:Synthesis Of Traumatoic (2E-Dodecenedioic) Acid From Dodecanedioic Acid
    标题:Synthesis Of Traumatoic (2E-Dodecenedioic) Acid From Dodecanedioic Acid
    摘要:
    DOI:10.1007/bf00957966

    海关参考信息

    专利信息


    专利号:US-9453037-B2
    优先权日:2011-07-28
    标 题 :Methylphenidate-prodrugs, processes of making and using the same
    发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
    权利人:KEMPHARM INC; KEMPHARM INC
    摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

    专利号:US-8865854-B2
    优先权日:2010-01-07
    标 题:Method of synthesizing tuneably high functionality in high molecular weight natural oil polyols
    发明人:GARRETT THOMAS M; DU XIAN XIAN
    权利人:GARRETT THOMAS M; DU XIAN XIAN
    摘要:Methods of one-pot synthesis of high molecular weight natural oil polyols having a functionality of between about 4 and about 8 are provided. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.

    专利号:US-9522192-B2
    优先权日:2012-12-13
    标 题:Polyethylene glycol derivatives of palmitoylethanolamide and analogous acylethanolamides
    发明人:CALIGNANO ANTONIO; D'AGOSTINO GIUSEPPE; LANERI SONIA; MELI ROSARIA; OSTACOLO CARMINE; RUSSO ROBERTO; SACCHI ANTONIA; TRONINO DIANA; DELLA VALLE FRANCESCO; DELLA VALLE MARIA FEDERICA; MARCOLONGO GABRIELE
    权利人:EPITECH GROUP SRL
    摘要:The synthesis of a series of Polyethylene glycol conjugates (esters and carbonates) of PEA and its analogous acylethanolamides, have higher water solubility and good hydrophilic/lipophilic balance, resulting in (i) improved accumulation in tissues (particularly skin and mucosae), (ii) prolonged release, and (iii) increased bioavailability. Improvement of PEA and analogous acylethanolamides levels in the tissues—particularly in the skin and mucosae—and their prolonged release is due to the improved bioavailability of related conjugates. Conjugates are able to extend the time frame in which PEA and analogous acylethanolamides exert their pharmacological effects.

    专利号:US-2025051183-A1
    优先权日:2021-12-13
    标题:Lithium metal oxide and a precursor for the synthesis thereof
    发明人:KEENE TONY
    权利人:UNIV DUBLIN
    摘要:The present invention relates to a compound of Formula I, Li(ox)]2[MlmM2nM3k(OH)pFq; wherein M1, M2 and M3 are metals; and X is a halogen chosen from F, Cl and Br; and m, n and k are, independently, a number between 0 and 5, the sum of m, n and k is 5; p and q are, independently, a number between 0 and 8, and the sum of p and q is 8; and to uses thereof and methods of synthesis thereof.

    专利号:US-11577963-B2
    优先权日:2020-01-17
    标 题 :Method of preparing sparsely pillared organic-inorganic hybrid compound
    发明人:IHM JISOON; PARK SEOK HWAN
    权利人:INNONEP INC
    摘要:Provided is a method of preparing a sparsely pillared organic-inorganic hybrid compound. The method of preparing an organic-inorganic hybrid compound includes: preparing a compound having a gibbsite structure by a method other than a hydrothermal synthesis method, using a trivalent metal cation source, an alkali imparting agent, and a first solvent (S10); and preparing an organic-inorganic hybrid compound by a method other than a hydrothermal synthesis method, using the compound of the gibbsite structure, a divalent metal cation source, dicarboxylic acid, and a second solvent (S20).

    专利号:EP-3060567-B1
    优先权日:2013-10-25
    标 题:Method for the synthesis of alkane-1-hydroxy-1,1-diphosphonic acid
    发明人:COGELS SAMUEL; NOTTÉ PATRICK PIERRE
    权利人:STRAITMARK HOLDING AG

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Jiang L, Liu P, Wang M, Deng Q, Wang J, Jiang Y, Zhu Y, Meng H, Lu X, Kong X, Chen L. Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with coronary heart disease. Front Cardiovasc Med. 2024 Nov 28;11:1508456. doi: 10.3389/fcvm.2024.1508456.
    2: Xue Y, Lin S, Chen M, Ke J, Zhang J, Fan Q, Chen Y, Chen F. Altered colonic microflora and its metabolic profile in mice with acute viral myocarditis induced by coxsackievirus B3. Virol J. 2024 Nov 16;21(1):295. doi: 10.1186/s12985-024-02571-z.
    3: Jiang D, Zhao J, Zheng J, Zhao Y, Le M, Qin D, Huang Q, Huang J, Zhao Q, Wang L, Dong X. LOX-mediated ECM mechanical stress induces Piezo1 activation in hypoxic-ischemic brain damage and identification of novel inhibitor of LOX. Redox Biol. 2024 Oct;76:103346. doi: 10.1016/j.redox.2024.103346. Epub 2024 Sep 7.

    合成参考文献

    合成方法参考DOI号:10.1007/BF00957966
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知