CAS: 184962-88-7; (S)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-3-(3,4-Dimethoxyphenyl)Propanoic Acid
该化合物是一种受保护的氨酸,通常用于peptide合成,具有9-氟乙氧碳基(FMOC)组,作为氨基功能的保护组,在合成过程中可以有选择地作出反应;苯丙烯的侧链上有两种甲氧基组,可增强它的溶性性和稳定性,使之适合各种有机反应;这种化合物通常用于固相聚聚,在基本条件下可以轻易去除氨基酸,便利依次添加氨基酸;其结构特征有助于其在开发含有特定生物活动的化物方面的作用,使其在制药和生物化学研究中具有价值;此外,众所周知,FMOC-34-甲基氧基-L苯拉尼的纯性和稳定性相对较高,对于在peptide合成中实现高产量至关重要.
- 英文名称(S)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-3-(3,4-Dimethoxyphenyl)Propanoic Acid
- 中文名称(S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-3-(3,4-二甲氧基苯基)丙酸
- IUPAC名称(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid
- 其它别名Fmoc-3,4-二甲氧基-L-苯丙氨酸; Fmoc-3,4-Dimethoxy-L-Phenylalanine
- CAS编号184962-88-7
- MFCD编号:MFCD01317730
- 分子式:C26H25NO6分子量:447.48
- 产品CID: 946700
- 产品分类有机原料→生命科学→氨基酸及其衍生物→酪氨酸及其衍生物
相似化合物
32161-30-1 55-59-4 33605-56-0物理性质
MSDS等安全信息
上下游产品
CAS号32161-30-1 3,4-二甲氧基-L-苯丙氨酸 | CAS号82911-69-1 9-芴甲基-N-琥珀酰亚胺碳酸酯合成工艺路线路线简述
📜3,4-二甲氧基-L-苯丙氨酸,9-芴甲基-N-琥珀酰亚胺基碳酸酯置于sodium Carbonate体系中,用 1,4-二氧六环 用作溶剂,化学反应 1.5H,以93%的收率获得fmoc-L-3,4-二甲氧基苯基丙氨酸
参考文献:New Synthetic Amino Acids For The Design And Synthesis Of Peptide-Based Metal Ion Sensors
标题:New Synthetic Amino Acids For The Design And Synthesis Of Peptide-Based Metal Ion Sensors
摘要:The Syntheses Of Two New Nonstandard Amino Acids,Flu (6) And Ybp (20),And A New Synthesis Of Dmd (12) Are Reported. These Residues Exhibit Fluorescence,Metal-Coordination,And Fluorescence-Quenching Properties,Respectively. These Building Blocks Have Been Incorporated Into Peptides Via Solid Phase Peptide Synthesis To Afford The Prototype Fur A Photoinduced Electron Transfer-Based Metal Ion Chemosensor. The Fluorescence Of The Peptides Is Modulated Upon Metal Binding. This Results From A Metal. Ion-Induced Conformational Change That Brings The Side Chains Of The Flu And Dmd Amino Acids Into Proximity,Thereby Favoring Photoinduced Electron Transfer (Pet) Fluorescence Quenching.
Doi:10.1021/jo961466W
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2907210001-间苯二酚
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8598089-B2
优先权日:2003-12-17
标题 :Methods for synthesis of encoded libraries
发明人：MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A
权利人:MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A; GLAXOSMITHKLINE LLC
摘要:The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
专利号:US-8410028-B2
优先权日:2003-12-17
标 题:Methods for synthesis of encoded libraries
发明人：MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A
权利人:MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A; GLAXOSMITHKLINE LLC
摘要:The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
专利号:US-2007042401-A1
优先权日:2003-12-17
标题 :Methods for synthesis of encoded libraries
专利号:US-2012245040-A1
优先权日:2003-12-17
标题 :Methods for synthesis of encoded libraries
专利号:US-2009062147-A1
优先权日:2003-12-17
标 题:Methods for synthesis of encoded libraries
专利号:US-7972994-B2
优先权日:2003-12-17
标 题 :Methods for synthesis of encoded libraries
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
合成方法参考DOI号:10.1021/jo961466w
📝 需求与反馈
尽可能描述清楚需求与问题信息
