CAS: 18463-25-7; ((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-Hydroxy-2-(Hydroxymethyl)Phenoxy)Tetrahydro-2H-Pyran-2-yl)Methyl Benzoate
该化合物是一种玻璃表面化合物,其特点是存在一种与苯球结构相连的玻璃表面,其特征是玻璃表面表面,其成分为一种氢氧基化合物组和芳香环上的一个液氧氧化物组,有助于其潜在的生物活动.附在玻璃表面表面的苯碳基化合物组增强了其亲脂性,并可能影响其与生物目标的相互作用.像这样的玻璃表面经常显示出各种药理特性,包括抗氧化剂和防炎活动,因为存在苯球成分.这种玻璃表面结构还可能影响生物系统的溶解和稳定性.
- 英文名称((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-Hydroxy-2-(Hydroxymethyl)Phenoxy)Tetrahydro-2H-Pyran-2-yl)Methyl Benzoate
- 中文名称Nigracin; 4-羟基-2-(羟基甲基)苯基 6-苯甲酰 β-D-吡喃葡萄糖苷
- IUPAC名称((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-hydroxy-2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-2-yl)methyl benzoate
- 其它别名Beta-D-Glucopyranoside 4-Hydroxy-2-(Hydroxymethyl)Phenyl 6-Benzoate; Poliothyrsoside; Xylosmoside; Nigracin; β-D-Glucopyranoside, 4-Hydroxy-2-(Hydroxymethyl)Phenyl, 6-Benzoate
- CAS编号18463-25-7
- MFCD编号:MFCD20260826
- 分子式:C20H22O9分子量:406.39
- 产品CID: 945820
- 产品分类天然产物 → 酚类
物理性质
MSDS等安全信息
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海关参考信息
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主要参考文献
1: Sashidhara KV, Singh SP, Varshney S, Beg M, Gaikwad AN. Poliothrysoside and its derivatives as novel insulin sensitizers potentially driving AMPK activation and inhibiting adipogenesis. Eur J Med Chem. 2014 Oct 30;86:570-7. doi: 10.1016/j.ejmech.2014.09.015. Epub 2014 Sep 6. doi: 10.1016/j.ejmech.2012.12.019. Epub 2012 Dec 16. doi: 10.1021/np300059n. Epub 2012 Mar 22. doi: 10.1016/j.jep.2010.04.045. Epub 2010 May 8. Chinese. h
合成参考文献
参考文献:10.1016/j.tet.2008.04.022
摘要:Chai X, Bai C, Shi H, Xu Z, Ren H, Li F, Lu Y, Song Y, Tu P. Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa orientalis. Tetrahedron. 2008 Jun;64(24):5743–7. doi: 10.1016/j.tet.2008.04.022.
参考文献:10.1080/10575639308043838
摘要:Gibbons S, Gray AI, Waterman PG. Poliothrysins: Novel Hydroxycyclohexenone Esters from the Leaves of Poliothrysis sinensis. Natural Product Letters. 1993 Aug 01;3(1):59–64. doi: 10.1080/10575639308043838.
参考文献:10.1124/mol.119.115964
摘要:Lee TD, Lee OW, Brimacombe KR, Chen L, Guha R, Lusvarghi S, Tebase BG, Klumpp-Thomas C, Robey RW, Ambudkar SV, Shen M, Gottesman MM, Hall MD. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology. 2019 Nov;96(5):629–40. doi: 10.1124/mol.119.115964.
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