CAS: 136415-83-3; 3-(3-Chlorophenyl)Propanal

该化合物是一种有机化合物,其特征为:甲状腺功能组和氯化芳香环;该化合物的特征为:丙烯酰胺脊柱,由三碳链组成,该链中的一种碳被替换为3-氯苯组;苯环上存在氯原子,影响其化学再活动性和物理特性,如溶液和沸点. 通常,由于甲状腺组的电活性性质,此类化合物可能会表现出中度至高度的再活动,使其在各种合成应用中有用,包括有机合成,并作为中间体,用于生产药品或农业化学品.此外,氯化芳香结构可能会带来独特的生物活动,这可能会引起对医药化学的兴趣.在处理和储存时,应当参考安全数据,因为氯化化合物可能对环境和健康造成风险.

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上下游产品

3-(3-chlorophenyl)propanol 3-iod°Chlorobenzene allyl alcohol carbon monoxide 1-chloro-3-(4,4-dibromobut-3-en-1-yl)benzene 5-(3-{[3-(3-Chloro-phenyl)-propyl]-amino}-propyl)-thiophene-2-carboxylic acid methyl ester 5-[(3-chlorophenyl)methyl]thiazol-2-amine

合成工艺路线路线简述

    📜3-氯苯乙烯置于pb(Oac)4体系中,用 二氯甲烷,三氟乙酸 用作溶剂,化学反应生成3-(3-氯苯基)丙醛
    参考文献:Cyclic Regimens Using Cyclocarbamate And Cyclic Amide Derivatives
    标题:Cyclic Regimens Using Cyclocarbamate And Cyclic Amide Derivatives
    摘要:本发明涉及循环联合疗法和方案,利用与孕激素相结合的取代吲哚啉衍生物化合物,其是孕激素受体拮抗剂,具有以下通用结构:其中a和b是独立的取代基,选自s,Ch或n;前提是当a为s时,B为ch或n;当b为s时,A为ch或n;A和b不能同时为ch;当a和b均等于n时,一个n可以选择性地被取代为c1至c6烷基;R1和r2是独立的取代基,选自h,C1至c6烷基,取代的c1至c6烷基,C2至c6烯基,取代的c2至c6烯基,C2至c6炔基,取代的c2至c6炔基,C3至c8环烷基,取代的c3至c8环烷基,芳基,取代的芳基,杂环,取代的杂环,Cora或nrbcora;或r1和r2融合形成可选择性取代的3至8成员螺环烷基,烷基,烯基或杂环环,其中杂环环包含选自o,S和n的一到三个杂原子;或其药学上有用的盐.这些治疗方法可用于避孕.

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    专利信息


    专利号:US-11225655-B2
    优先权日:2010-04-16
    标题:Bi-functional complexes and methods for making and using such complexes
    发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
    权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
    摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

    专利号:US-4018820-A
    优先权日:1970-07-09
    标题 :Chemical synthesis
    发明人:FRIED JOSEF
    权利人:UNIV CHICAGO
    摘要:This invention relates to pharmacologically active compounds of the formula: ##STR1## wherein Z is trans-CH=CH, C.tbd.C; or CH 2 -CH 2 ; n M is H or lower alkyl; n n is an integer of from 2 to 5; n X is alkyl; n W is H or OR, wherein R is H, acyl, or alkyl; and n Each Y is H, OH or alkoxy; n And to novel intermediates and processes useful in the production thereof.

    专利号:US-4175201-A
    优先权日:1973-05-18
    标 题 :Chemical synthesis
    发明人:FRIED JOSEF
    权利人:CHICAGO UNIVERSITY
    摘要:This invention relates to pharmacologically active compounds of the formula: ##STR1## wherein Z is trans--CHâ•?CH, C.tbd.C; or CH 2 --CH 2 ; n M is H or lower alkyl; n n is an integer of from 2 to 5; n X is alkyl; n W is H or OR, wherein R is H, acyl, or alkyl; n each Y is H, OH or alkoxy; n and to novel intermediates and processes useful in the production thereof.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献

    参考DOI号:10.1016/j.bmcl.2009.05.119
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