CAS: 1131-15-3; 3-Phenyldihydrofuran-2,5-Dione

相似化合物

116668-56-5 1225521-38-9 1226409-57-9

上下游产品

2-phenylsuccinic acid maleic anhydride benzene 1-(2'-methylpropenylidene)-2-phenylcyclopropane1-(p-tolyl)-3-phenylpyrrolidine-2,5-dione 3,5,5-triphenyltetrahydrofuran-2(3H)-one 1-ethyl-3-phenyl-pyrrolidine-2,5-dione N-diphenyl-succinamic acid2,N-diphenyl-succinamic acid

专利信息

专利号:US-9050586-B2
优先权日:2012-03-13
标 题:Enantioselective organic anhydride reactions
发明人：CONNON STEPHEN J; TALLON SEAN; CORNAGGIA CLAUDIO; MANONI FRANCESCO; TORRENTE ESTHER
权利人:CONNON STEPHEN J; TALLON SEAN; CORNAGGIA CLAUDIO; MANONI FRANCESCO; TORRENTE ESTHER; PROVOST FELLOWS & SCHOLARS COLLEGE OF THE HOLY UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
摘要:Disclosed herein is enantioselective synthetic method comprising reacting an enolisable C 4 -C 50 organic anhydride with a second compound selected from the group consisting of an aldehyde, a ketone, an aldimine, a ketimine or a Michael Acceptor in the presence of a bifunctional organocatalyst. The reaction may find particular utility in the enantioselective synthesis of medicinally relevant heterocycles, such as dihydroisocoumarins and dihydroisoquinolinones.