CAS: 532-11-6; 5-(4-Methoxyphenyl)-3H-1,2-Dithiole-3-Thione

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CAS号104-46-1 茴香脑 | CAS号4180-23-8 茴香烯 | CAS号75-15-0 二硫化碳 | CAS号100-06-1 对甲氧基苯乙酮 | CAS号25679-28-1 (Z)-anethol | CAS号140-67-0 草蒿脑 | CAS号831-30-1 5-(p-methoxyphe... | CAS号50849-98-4 3,3-dimercapto-... | CAS号18274-81-2 5-(4-羟基苯基)-3H-1... | CAS号19652-13-2 5-氨基-3-(4-甲氧苯基)... | CAS号100-63-0 苯肼 | CAS号1820-42-4 双(4-氯苯基)乙炔 | CAS号81385-69-5 4,5-Bis(4-chlor... | CAS号13232-76-3 3H-1,2-Dithiole... | CAS号4280-58-4 1-methoxy-4-[6-...

1-[2-氯-3,3,3-三氟-1-丙烯基]-4-甲氧基苯置于1,2,3,4,5,6,7,8-八硫杂环辛烷,四甲基乙二胺,Caesium Carbonate,Copper(I) Bromide体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 12.0H,以55%的收率获得产物胆维他
参考文献:一种铜催化合成的1,2-二硫-3-硫酮衍生物的 制备方法
标题:一种铜催化合成的1,2-二硫-3-硫酮衍生物的 制备方法
摘要:本发明公开了一种铜催化三氟丙炔脱氟硫环化合成的1,2‑二硫‑3‑硫酮衍生物,以2‑氯‑3,3,3‑三氟‑1丙烯化合物作为底物,通过在底物中加入溴化亚铜作为催化剂,碳酸铯作为碱,四甲基乙二胺作为配体,单质硫作为硫源在溶剂n,N‑二甲基甲酰胺中,于120oc下,搅拌反应12小时;反应结束后,过滤反应液,并用饱和氯化钠溶液将滤液萃取两次,反萃一次,分离所得有机相用无水硫酸钠进行干燥后,再次过滤,并将滤液用旋转蒸发仪除去溶剂获得剩余物,通过硅胶柱对剩余物进行柱层分离,并经洗脱液进行淋洗,收集含有目标产物的流出液,合并流出液并经过真空浓缩除去溶剂获得目标产物.本发明具有原料简单易得,制备工艺新颖,简单,污染少,耗能低,产率高的优点.

专利信息

专利号:US-9267213-B1
优先权日:2005-03-25
标题:Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
发明人：MAURER KARL; COOPER JOHN J
权利人:CUSTOMARRAY INC
摘要:There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

专利号:WO-2017046598-A1
优先权日:2015-09-16
标题:Treatment of acute inflammatory disorders
发明人：CRISANTI ANDREA; CANAVESE MIRIAM
权利人:CRISANTI ANDREA; IMP INNOVATIONS LTD
摘要:The present invention relates to a VEGF receptor agonist for use in the treatment of an acute inflammatory disorder associated with the overproduction of pro-inflammatory cytokine, administered with an agent that induces the synthesis of Nrf2. The invention also relates to pharmaceutical combinations comprising a VEGF receptor agonist and an agent that induces the synthesis of Nrf2, and kits comprising these agents. The described uses, combinations and methods may prevent or reduce the dis-regulated activation of an inflammatory response and reduce endothelial damage.

专利号:US-2006194971-A1
优先权日:2005-02-24
标 题 :Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neruotransmission
发明人：DRUKARCH BENJAMIN; SCHOFFELMEER ANTON N; FEENSTRA ROELOF W; CHRISTEN MARIE-ODILE; BURGOT JEAN-LOUIS; CHOLLET MARYLENE; IWEMA BAKKER WOUTER I; VAN VLIET BERNARD J; TULP MARTINUS T
权利人:DRUKARCH BENJAMIN; SCHOFFELMEER ANTON N; FEENSTRA ROELOF W; CHRISTEN MARIE-ODILE; BURGOT JEAN-LOUIS; CHOLLET MARYLENE; IWEMA BAKKER WOUTER I; VAN VLIET BERNARD J; TULP MARTINUS T
摘要:The present disclosure relates to dithiolethione derivatives as monoamino oxidase inhibitors, in particular MAO-B inhibitors, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said dithiolethiones derivatives. The present disclosure also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect. In embodiments of the present disclosure specific compounds disclosed herein are used for the manufacture of a medicament useful in the treatment, amelioration or prevention of conditions associated with dysfunction of monoamine neurotransmission. The compounds have the general formula (1) n nwherein the symbols have the meanings given in the specification.

专利号:US-RE45612-E
优先权日:2001-05-04
标 题 :Corrosion inhibitor composition applicable for aluminum and steel protection and procedure
发明人：SINKO JOHN
权利人:SINKO JOHN; MD FIFTH WARD PROPERTIES INC
摘要:A corrosion-inhibiting composition for application to a metal substrate, such as aluminum or steel, and in connection with a paint, and the synthesis of the composition. The active inhibitor constituent of the composition can be selected from the group consisting of 2,5-dimercapto-1,3,4 thiadiazole (DMTD), 2,4-dimercapto-s-triazolo-[4,3-b]-1,3-4-thiadiazole, trithiocyanuric acid (TMT), and derivatives of DMTD and TMT, including various N— or S— and N, N—, S— and N—,S-substituted derivatives of DMTD, including salts of DMTD of the general formula: M(DMTD) n , where n=1,2 or 3, and M is a metal cation and preferably M=Zn(II), Bi(III), Co(II), Ni(II), Cd(II), Pb(II), Ag(I), Sb(III), Cu(II), Li(I), Ca(II), Sr(II), Mg(II), La(III), Ce(III), Pr(III), Al(III) or Zr(IV). DMTD, TMT, and their derivatives may also be combined with phosphates, molybdates, borates, silicates, tungstates, phosphotungstates, phosphomolybdates, cyanamides, carbonates, SiO 2 and mixtures thereof.

专利号:CN-109134789-A
优先权日:2018-07-27
标 题:A kind of synthesis of fluorine-containing block copolymer and preparation method of micelle

专利号:CA-2642194-A1
优先权日:2006-02-21
标题 :Processes for the convergent synthesis of calicheamicin derivatives