CAS: 41438-18-0; 4-Hydroxy-2-Methylbenzaldehyde

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CAS号206122-92-1 2-methyl-4-prop... | CAS号67-66-3 氯仿 | CAS号108-39-4 间甲酚 | CAS号661481-12-5 Benzaldehyde, 4... | CAS号80193-36-8 4-(1,3-dithiola... | CAS号95-65-8 3,4-二甲酚 | CAS号52289-54-0 4-甲氧基-2-甲基苯甲醛 | CAS号100-84-5 间甲基苯甲醚 | CAS号557-21-1 氰化锌 | CAS号4885-02-3 1,1-二氯甲醚 | CAS号14143-26-1 3-甲基-4-氰基-苯酚 | CAS号206122-92-1 2-methyl-4-prop... | CAS号52289-54-0 4-甲氧基-2-甲基苯甲醛 | CAS号578-39-2 4-羟基-2-甲基苯甲酸 | CAS号103203-88-9 3-(4-hydroxy-2-... | CAS号101093-56-5 4-苄氧基-2-甲基苯甲醛 | CAS号22574-58-9 4-(hydroxymethy...

间甲基苯甲醚置于溴,吡啶盐酸盐,Magnesium体系中,用 四氯化碳 作为反应溶剂,化学反应生成 2-甲基-4-羟基苯甲醛
参考文献:取代基对邻甲苯甲醛光化学的影响
标题:取代基对邻甲苯甲醛光化学的影响
摘要:研究了4-氧基和4,5-二氧基取代基对2-甲基苯甲醛向邻喹啉二甲烷(o-Qdms)的光化学转化的影响.4-甲氧基或4和5-甲氧基取代基的存在阻止了o-Qdm的光化学形成,而4-乙酰氧基和4,5-二乙酰氧基-2-甲基苯甲醛以及相应的甲磺酸酯和甲苯磺酸酯则成功转化为o-Qdm.
DOI:10.1016/s0040-4039(00)80821-7

专利信息

专利号:US-9919064-B2
优先权日:2012-08-10
标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents
发明人：CESATI RICHARD R; RADEKE HEIKE S; PANDEY SURESH K; PUROHIT AJAY; ROBINSON SIMON P
权利人:LANTHEUS MEDICAL IMAGING INC
摘要:The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

专利号:WO-2021083438-A1
优先权日:2019-10-30
标 题:Inhibitors of purine nucleoside phosphorylase - synthesis and use thereof for treatment of t-cell acute lymphoblastic leukemia and lymphoma
发明人：SKACEL JAN; JANEBA ZLATKO; MERTLIKOVA KAISEROVA HELENA
权利人:USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I
摘要:The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

专利号:US-7671085-B2
优先权日:2002-11-15
标 题 :Non-steroidal farnesoid X receptor modulators and methods for the use thereof
发明人：DOWNES MICHAEL R; EVANS RONALD M
权利人:SALK INST FOR BIOLOGICAL STUDI
摘要:The efficient regulation of cholesterol synthesis, metabolism, acquisition, and transport is an essential component of lipid homeostasis. The farnesoid X receptor (FXR) is a transcriptional sensor for bile acids, the primary product of cholesterol metabolism. Accordingly, the development of potent, selective, small molecule agonists, partial agonists, and antagonists of FXR would be an important step in further deconvoluting FXR physiology. In accordance with the present invention, the identification of novel potent FXR activators is described. Two derivatives of invention compounds, bearing stilbene or biaryl moieties, contain members that are the most potent FXR agonists reported to date in cell-based assays. These compounds are useful as chemical tools to further define the physiological role of FXR as well as therapeutic leads for the treatment of diseases linked to cholesterol, bile acids and their metabolism and homeostasis.

专利号:US-2018318456-A1
优先权日:2012-08-10
标题:Compositions, methods, and systems for the synthesis and use of imaging agents

专利号:US-2020230264-A1
优先权日:2012-08-10
标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents

专利号:WO-2014026079-A2
优先权日:2012-08-10
标题 :Compositions, methods, and systems of the synthesis and use of imaging agents