CAS: 2872-52-8; 2-(Ethyl(4-((4-Nitrophenyl)Diazenyl)Phenyl)Amino)Ethanol

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CAS号92-50-2 2-(N-乙基苯氨基)乙醇 | CAS号100-01-6 对硝基苯胺 | CAS号1355342-65-2 | CAS号14368-49-1 4-nitrobenzened... | CAS号103553-48-6 分散红1甲基丙烯酸酯

Prop-2-Enyl 3-[2-[n-Ethyl-4-[(4-Nitrophenyl)Diazenyl]Anilino]Ethoxycarbonyloxymethyl]-5-[[2-[[2-(3-Hydroxy-6-Oxoxanthen-9-yl)Benzoyl]-Methylamino]Ethyl-Methylcarbamoyl]Oxymethyl]-4-[[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Phenyl]Methoxy]Benzoate置于四(三苯基膦)钯,双氧水,三正丁基氢锡,溶剂黄146体系中,用 四氢呋喃 用作溶剂,化学反应 0.25H,反应生成分散红 1
参考文献:A Simple Fret-Based Modular Design For Diagnostic Probes
标题:A Simple Fret-Based Modular Design For Diagnostic Probes
摘要:近年来,开发具有光学作用模式的分子探针的工作取得了巨大的进展.探针通常基于荧光特性的变化产生可检测的信号.在此,我们展示了自免疫分子适配器作为基于fret技术的开关探针平台的潜力.该探针配备有相同的荧光基对或荧光基/淬灭基fret对以及一个触发底物.在目标分析物与触发底物反应后,自免疫适配器自发释放两个染料分子,从而解除fret效应.结果产生了一个新的可测量的荧光信号.获得的荧光可用于定量分析物.探针设计的模块化结构将允许基于fret激活技术制备各种化学探针.
Doi:10.1039/c1Ob06667F

专利信息

专利号:US-2023235372-A1
优先权日:2020-06-12
标题:Ab-initio, template-independent synthesis of nucleic acids using thermostable enzymes
发明人：RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; RAHIER RENAUD
权利人:SYNHELIX
摘要:The invention relates to the field of nucleic acid synthesis or sequencing, more specifically to methods for ab-initio synthesis of nucleic acids, comprising contacting a nucleotide with a free 3′-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3′-hydroxyl group of the nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of both ab-initio single-stranded nucleic acid synthesis activity and template-independent terminal nucleotidyl transferase activity.

专利号:US-2023235373-A1
优先权日:2020-06-12
标 题:Controlled template-independent synthesis of nucleic acids using thermostable enzymes
发明人：RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; RAHIER RENAUD
权利人:SYNHELIX
摘要:The invention relates to methods for template-independent synthesis of nucleic acids, comprising iteratively contacting an initiator sequence comprising a 3′-end nucleotide with a free 3′-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3-hydroxyl group of the 3-end nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of template-independent terminal nucleotidyl transferase activity but are devoid of a template-independent primase activity.

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-8759508-B2
优先权日:2007-05-18
标 题 :Chromophoric silyl protecting groups and their use in the chemical synthesis of oligonucleotides
发明人：DELANEY MICHAEL OREN
权利人:DELANEY MICHAEL OREN; GE HEALTHCARE DHARMACON INC
摘要:The compounds are of class of chromophoric 1,2,3-triazolyl equipped silyl linking groups that are useful in the chemical synthesis of RNA. An example of a nucleoside comprising this group is

专利号:WO-2023225524-A1
优先权日:2022-05-17
标题:Preparation of highly concentrated mrna
发明人：GENG MARK; SINOIMERI JAMES
权利人:MODERNATX INC
摘要:Provided herein are compositions of highly concentrated mRNA and related methods for preparation and use of the compositions as mRNA process intermediates in the synthesis of therapeutic and prophylactic mRNA formulations.

专利号:US-7671141-B2
优先权日:2005-06-30
标题:Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same
发明人：HSU TZU-CHIEN; CHEN CHIEN-FAN; WU SHOU-SHIUN
权利人:UNIV NAT SUN YAT SEN
摘要:Disclosed herein are second order nonlinear optic polyimide polymers comprising repeating units represented by the formula: n nwherein each of the substituents is given the definition as set forth in the Specification and Claims. Also disclosed are the preparation processes of these polymers, chromophore-forming compounds for synthesis of these polymers, and the intermediate polymers thereof. The second order nonlinear optic polyimide polymers of formula (I) may be used in the manufacture of electro-optic (EO) devices, such as electro-optic waveguide devices.