CAS: 1591-99-7; 2,3-Dimethylphenylisocyanate

上下游产品

bis(trichloromethyl) carbonate 2,3-Dimethylaniline 1-(2,3-Dimethyl-phenyl)-3-(1-methyl-1-p-tolyl-ethyl)-urea 1-(2,3-Dimethyl-phenyl)-3-(1-methyl-1-o-tolyl-ethyl)-urea 1-(2,3-Dimethyl-phenyl)-3-(1-methyl-1-m-tolyl-ethyl)-urea

📜三光气,2,3-二甲基苯胺置于三乙胺体系中,用 1,2-二氯乙烷 用作溶剂,化学反应 2.0H,反应生成异氰酸235-二甲基苯酯
参考文献:钯(0)催化的碳氢键官能团用于合成吲哚并喹唑啉酮
标题:钯(0)催化的碳氢键官能团用于合成吲哚并喹唑啉酮
摘要:吲哚喹唑啉酮环系统作为药效团引起了相当大的关注,因为它显示出各种生物活性.已报道的该化合物的合成方法简单,直接,但对直接合成c-6位上带有亚甲基的吲哚并喹唑啉酮无效.钯(0)chloroquinazolinone的催化的环化通过ç ħ官能度为indoloquinazolinone衍生物的简明合成显影.在c-6位置存在取代基对于以高收率获得产物很重要.反应中间物,尤其是所述n个的构象 ç 钯键角,是用于该反应的区域选择性重要.
Doi:10.1002/adsc.201400078

专利信息

专利号:US-10385167-B2
优先权日:2015-02-13
标题:Process for the synthesis of polyoxazolidinone compounds with high stability
发明人：MÃœLLER THOMAS ERNST; Gürtler Christoph; BASU SUSMIT; RANGHEARD CLAUDINE; RIVILLO DAVID; LEITNER WALTER; Köhler Burkhard
权利人:COVESTRO DEUTSCHLAND AG
摘要:The present invention relates to polyoxazolidinone compounds, a method for the production of polyoxazolidinone compounds, comprising the step of reacting a biscarbamate compound with a bisepoxide compound in the presence of a mono-carbamate, a mono-isocyanate and/or a mono-epoxide compound as chain regulator and a suitable base having a pK b value of ≤9 as catalyst. The invention further relates to the use of polyoxazolidinone compounds with high thermal stability.

专利号:US-11326018-B2
优先权日:2016-08-19
标 题:Process for the synthesis of polyoxazolidinone compounds
发明人：WEBER ANNA; RANGHEARD CLAUDINE; KESSLER MICHAEL; LEITNER WALTER; Gürtler Christoph; KOOPMANS CARSTEN; MÃœLLER THOMAS ERNST
权利人:COVESTRO DEUTSCHLAND AG
摘要:A method for the production of polyoxazolidinone compounds, comprising the step of reacting an isocyanate compound (A) with an epoxide compound (B) in the presence of a catalyst (C), wherein the isocyanate compound (A) comprises a isocyanate compound (A 1 ) wherein the a isocyanate compound (A1) comprising at least two isocyanate groups (I 1 ≥2), preferred two isocyanate groups (I 1 =2), wherein the epoxide compound (B) comprises a epoxide compound (B 1 ) and an epoxide compound (B 2 ), wherein the epoxide compound (B 2 ) is different from the epoxide compound (B 1 ) wherein the epoxide compound (B 1 ) comprising at least two terminal epoxide groups (F1≥2), preferred two terminal epoxide groups (F 1 =2), linked together by a linking group (L1) and the epoxide compound (B 2 ) comprising at least two terminal epoxide groups (F 2 ≥2)), preferred two terminal epoxide groups (F 2 =2), linked together by a linking group (L 2 ), wherein the linking group (L 2 ) comprises acyclic and covalent bonds to each other free of conjugated multiple bonds within the main chain, wherein the epoxide compound (B 2 ) is present in the epoxide compounds B 1 and B 2 , in an amount of ≥0.01 mol-% to <10 mol-%, preferred 1-9 mol-% more preferred 3-8 mol-% based on the molar ratio the terminal epoxide groups in the epoxide compound (B 1 ) and of the sum of the terminal epoxide groups in the epoxide compound (B 1 ) and terminal epoxide groups in the epoxide compound (B 2 ).

专利号:US-7273902-B2
优先权日:2003-09-05
标题:Stabilizer against hydrolysis for an ester-group-containing resin and a thermoplastic resin composition
发明人：TAKAHASHI IKUO; IIDA HIROTAKA; YANAGISAWA KEN-ICHI
权利人:NISSHIN SPINNING
摘要:A stabilizer against hydrolysis, which can solve conventional problems of a carbodiimide compound compounded in an ester-group-containing resin or a biodegradable plastic as a stabilizer against hydrolysis, such as poor heat resistance and a coloring problem due to yellowing, and can provide enhanced resistance against hydrolysis, and a thermoplastic resin composition of an ester-group-containing resin or a biodegradable plastic containing the same. Specifically, that the stabilizer against hydrolysis includes a carbodiimide composition comprising an aliphatic carbodiimide compound (A) and a phosphorus antioxidant (B), preferably the stabilizer contains a carbodiimide composition wherein a phosphorus antioxidant (B 1 ) is dispersed and present in the carbodiimide composition by admixing the phosphorus antioxidant (B 1 ) during synthesis of the aliphatic carbodiimide compound (A), and a thermoplastic resin composition having a superior stability against hydrolysis, characterized in that said stabilizer against hydrolysis is compounded in an easily hydrolysable resin (C).

专利号:US-9833457-B2
优先权日:2008-01-25
标题:Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors
发明人：MJALLI ADNAN M M; GADDAM BAPU; POLISETTI DHARMA RAO; KOSTURA MATTHEW J; GUZEL MUSTAFA
权利人:VTV THERAPEUTICS LLC
摘要:The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to psoriatic arthritis.

专利号:WO-2018033562-A1
优先权日:2016-08-19
标 题 :Process for the synthesis of polyoxazolidinone compounds

专利号:EP-3143060-B1
优先权日:2014-05-12
标题 :Catalysts for the synthesis of oxazolidinone compounds