CAS: 11021-13-9; (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-Hydroxy-4,4,8,10,14-Pentamethyl-17-((S)-6-Methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2S,3R,4S,5S)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Hept-5-En-2-yl)Hexadecahydro-1H-Cyclopenta[a]Phenanthren-3-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是一种天然的甘蓝,是人参中发现的主要活性成分之一,特别是在帕纳克斯人参中.它属于被称为沙邦因的化合物类别,其特征为沙邦因,其特征是非对流性,允许其与水利和水利恐惧环境互动.金蛋色表面Rb2因其潜在的药理特性而闻名,包括抗炎,抗氧化剂和...

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

2)-β-D-glucopyranosyl}-20-O-[α-L-arabinopyranosyl-(1->6)-β-D-glucopyranosyl]protopanaxadiol(20S)-3-O-{β-D-6-O-[(E)-but-2-enoyl]glucopyranosyl-(1-2)-β-D-glucopyranosyl}-20-O-[α-L-arabinopyranosyl-(1-6)-β-D-glucopyranosyl]protopanaxadiol 2malonyl-ginsenoside Rb2protopanaxadiol 2ginsenoside F2 ginsenoside Rd compound K

合成工艺路线路线简述

    📜(20S)-3-O-{β-D-6-O-[(E)-But-2-Enoyl]Glucopyranosyl-(1->2)-β-D-Glucopyranosyl}-20-O-[α-L-Arabinopyranosyl-(1->6)-β-D-Glucopyranosyl]Protopanaxadiol置于sodium Methylate体系中,用 甲醇 用作溶剂,化学反应 12.0H,反应生成人参皂苷rb2
    参考文献:人参根中酰化原人参二醇型人参皂苷
    标题:人参根中酰化原人参二醇型人参皂苷
    摘要:从最重要的中草药之一人参的根中分离出六种新的原人参二醇型人参皂苷,命名为人参皂苷 Ra4-Ra9(1-6,分别),以及 14 种已知的达玛烷型三萜皂苷.新化合物的结构通过光谱方法确定,包括 1D-和 2D-NMR,Hr-Ms 和化学转化为 (20S)-3-O-{β-D-6-O-[(E)-丁-2-烯酰基]吡喃葡萄糖基-(1->2)-β-D-吡喃葡萄糖基}-20-O-[β-D-吡喃木糖基-(1->4)-α-L-阿拉伯吡喃糖基-(1->6)-β-D-吡喃葡萄糖基]原人参二醇 (1),(20S)-3-O-[β-D-6-O-乙酰吡喃葡萄糖基-(1->2)-β-D-吡喃葡萄糖基]-20-O-[β-D-吡喃木糖基-(1->4)-α-L-阿拉伯吡喃糖基-(1->6)-β-D-吡喃葡萄糖基]原人参二醇(2),(20S)-3-O-{β-D-6-O-[(E)-But-2-Enoyl]吡喃葡萄糖基-(1->2)-β-D-吡喃葡萄糖基}-20-O-[β-
    Doi:10.1002/cbdv.201000196

    海关参考信息

    专利信息


    专利号:ES-2209197-T3
    优先权日:1997-08-08
    标 题 :USE OF GINSENOSIDE RB1 TO STIMULATE THE SYNTHESIS OF ELASTINE.

    专利号:FR-2767057-A1
    优先权日:1997-08-08
    标 题:USE OF GINSENOSIDE RB1 AS AN AGENT FOR STIMULATING THE SYNTHESIS OF ELASTINE

    专利号:US-2014328952-A1
    优先权日:2011-12-21
    标题:Topical compositions
    发明人：FLAVIN DANA
    权利人:FLAVIN DANA
    摘要:This invention provides compositions and methods of manufacturing such compositions that employ GRAS compounds which can act to promote the generation of stem, epidermal or other skin cells in the epidermis, activation of collagen synthesis, activation of hyaluronic acid synthesis, enhanced skin hydration, and dermal healing by stimulating stem cell and fibroblast migration to sites of needed repair. These compositions and methods are useful for rejuvenating the skin and for treating some skin-related aging or other dermal damaging conditions, including wrinkle reduction and treatment of minor dermal wounds.

    专利号:CN-105671159-A
    优先权日:2016-03-01
    标 题:Method for Screening Key Genes of Notoginseng Saponins Synthesis Based on Metabolites and Gene Expression

    专利号:EP-1001740-A1
    优先权日:1997-08-08
    标题 :USE OF THE Rb 1? GINSENOSIDE FOR STIMULATING ELASTIN SYNTHESIS

    专利号:WO-9907338-A1
    优先权日:1997-08-08
    标题:USE OF THE Rb1 GINSENOSIDE FOR STIMULATING ELASTIN SYNTHESIS

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Shin HS, Park SY, Hwang ES, Lee DG, Mavlonov GT, Yi TH. Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model. Biol Pharm Bull. 2014;37(5):755-63. doi: 10.3109/14756366.2013.871006. Epub 2014 Mar 25. doi: 10.1016/j.ejphar.2014.02.024. Epub 2014 Mar 12. doi: 10.1007/s10529-014-1472-y. Epub 2014 Feb 23. doi: 10.4014/jmb.1605.05052. doi: 10.1016/j.canlet.2012.01.045. Epub 2012 Feb 7. Epub 2016 Oct 18.
    8: Park SH, Seo W, Eun HS, Kim SY, Jo E, Kim MH, Choi WM, Lee JH, Shim YR, Cui CH, Kim SC, Hwang CY, Jeong WI. Protective effects of ginsenoside F2 on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation in mice. Biochem Biophys Res Commun. 2016 Sep 30;478(4):1713-9. doi: 10.1016/j.bbrc.2016.09.009. Epub 2016 Sep 3. doi: 10.5142/jgr.2012.36.4.418.
    10: Li L, Shin SY, Lee SJ, Moon JS, Im WT, Han NS. Production of Ginsenoside F2 by Using Lactococcus lactis with Enhanced Expression of β-Glucosidase Gene from Paenibacillus mucilaginosus. J Agric Food Chem. 2016 Mar 30;64(12):2506-12. doi: 10.1021/acs.jafc.5b04098. Epub 2015 Nov 5. doi: 10.1371/journal.pone.0085727. eCollection 2014.

    合成参考文献


    参考文献:10.1111/j.2042-7158.1996.tb03967.x
    摘要:Yokozawa T, Yasui T, Oura H. Molecular biological analysis of the effects of ginsenoside-Rb2 on albumin mRNA in streptozotocin-induced diabetic rats. J Pharm Pharmacol. 1996 Jul;48(7):763–7. doi: 10.1111/j.2042-7158.1996.tb03967.x.
    参考文献:10.1016/0378-8741(86)90089-9
    摘要:Ng TB, Wong CM, Yeung HW. Effect of ginsenosides Rg1, Rc and Rb2 on hormone-induced lipolysis and lipogenesis in rat epididymal fat cells. J Ethnopharmacol. 1986 Jun;16(2-3):191–9. doi: 10.1016/0378-8741(86)90089-9.
    参考文献:10.1248/bpb.17.635
    摘要:SATO K, MOCHIZUKI M, SAIKI I, YOO Y, SAMUKAWA K, AZUMA I. Inhibition of Tumor Angiogenesis and Metastasis by a Saponin of Panax ginseng, Ginsenoside-Rb2. Biological & Pharmaceutical Bulletin. 1994;17(5):635–9. doi: 10.1248/bpb.17.635.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知