CAS: 82679-58-1; (2R,3S)-Benzyl 2-Amino-3-Hydroxybutanoate
该化合物是有机合成和制药应用中广泛使用的手艺建筑块,其关键优点包括高对应纯度,对非对称合成和浸泡物的修改很有价值.苯基酯组提高了有机溶剂的溶性,便利了在温和条件下的反应.该化合物是培养生物活性分子的多用途中间体,特别是在发展消毒和酶抑制剂方面.在标准储存条件下,其稳定性确保合成工作流程的一贯性能.该产品具有可靠的再生性,符合研究和工业规模应用的严格质量要求.
- 英文名称(2R,3S)-Benzyl 2-Amino-3-Hydroxybutanoate
- 中文名称D-苏氨酸苄酯
- IUPAC名称benzyl D-threoninate
- 其它别名D-Threonine Benzyl Ester; D-Threonine Phenylmethyl Ester; Benzyl (2R,3S)-2-Amino-3-Hydroxybutanoate; D-Threonine Benzyl Ester Usp/ep/bp; Benzyl D-Threoninate
- CAS编号82679-58-1
- MFCD编号:MFCD02094345
- 分子式:C11H15NO3分子量:209.24
- 产品CID: 1816916
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
上下游产品
CAS号632-20-2 D-苏氨酸 | CAS号100-51-6 苯甲醇合成工艺路线路线简述
- 合成目标产物 D-Threonine Benzyl Ester 主要起始原料 D-Threonine And Benzyl Alcohol
- 100-51-6 + 632-20-2 = 82679-58-1
反应条件:1.1 Catalysts: P-Toluenesulfonic Acid Solvents: Benzene; Overnight,Reflux
标题:Stereoselective Synthesis Of Natural And Non-Natural Thomsen-Nouveau Antigens And Hydrazide Derivatives
作者:Shaik,Ahmad Ali; Et Al
参考文献:Organic Letters 日期:2015 卷标:17(11) 页码:2582-2585]
100-51-6 + 632-20-2 = 82679-58-1
反应条件:1.1 Catalysts: P-Toluenesulfonic Acid Solvents: Benzene; 25 H,Reflux
标题:Synthesis Of δ-(L-α-Aminoadipoyl)-L-Cysteinyl-D-(O-Methyl)-D-Allothreonine A Substrate For Isopenicillin-N Synthase And Its O-Methyl-D-Threonine Epimer
作者:Petursson,Sigthor; Et Al
参考文献:Tetrahedron 日期:1998 卷标:54(22) 页码:6001-6010
📜D-苏氨酸,苯甲醇置于对甲苯磺酸体系中,用 苯 作为反应溶剂,化学反应生成 D-苏氨酸苄酯
参考文献:Stereoselective Synthesis Of Natural And Non-Natural Thomsen-Nouveau Antigens And Hydrazide Derivatives
标题:Stereoselective Synthesis Of Natural And Non-Natural Thomsen-Nouveau Antigens And Hydrazide Derivatives
摘要:A Selective Glycosylation Strategy Enabling Access To All Stereochemical Combinations Of Tumor Associated Thomsen-Nouveau (Tn) Antigen,D-Galnac-O-Ser/thr,Has Been Developed. The Key Component For Selectivity Is The Phthalimide-Protected D-Or L-Amino Acid Acceptors Which Allow Access To Alpha-Or Beta-Anomers In Excellent Yields (72-96%) And Selectivity (Similar To 100%) When Appropriate C-2 Substitution Is Installed. The Glycoamino Acid Intermediates Were Divergently Converted To Tn-Based Carboxylates Or To Hydrazides By Tandem Pd-C Debenzylation Followed By Treatment With Hydrazine Hydrate Or Hydrazine Hydrate Treatment Alone.
DOI:10.1021/acs.Orglett.5B00512
海关参考信息
- 2902300000-甲苯
2905122000-异丙醇
2905399001-1,3-丙二醇
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Studies On The Biosynthesis Of Clavulanic Acid. Part 5. Absolute Stereochemistry Of Proclavaminic Acid, The Monocyclic Biosynthetic Precursor Of Clavulanic Acid作者:Keith H. Baggaley,Stephen W. Elson,Neville H. Nicholson,John T. Sime
摘要:Carried Out With Enantiomerically Pure Threonine Derivatives To Confirm That The Formation Of The β-Lactam Moiety Did Not Impair The Integrity Of The α- And β-Chiral Centres And That The Enzymatic Deacylation Reaction Was Capable Of Resolving The α-Centre Of An α-Amino-β-Hydroxy Acid. The Enantiomeric Purity Of Intermediates Was Determined Using Hplc, 1H Nmr Spectroscopy Utilising The Chiral Solvating Reagents
合成参考文献
合成方法参考DOI号:10.1016/S0040-4020(98)00280-4
📝 需求与反馈
尽可能描述清楚需求与问题信息
