专利号:US-7615169-B2 优先权日:2004-09-20 标题 :Method for synthesis of colloidal nanoparticles 发明人:STROUSE GEOFFREY FIELDING; GERBEC JEFFREY A; MAGANA DONNY 权利人:UNIV CALIFORNIA 摘要:A method for synthesis of high quality colloidal nanoparticles using comprises a high heating rate process. Irradiation of single mode, high power, microwave is a particularly well suited technique to realize high quality semiconductor nanoparticles. The use of microwave radiation effectively automates the synthesis, and more importantly, permits the use of a continuous flow microwave reactor for commercial preparation of the high quality colloidal nanoparticles.
专利号:US-2021107859-A1 优先权日:2018-04-06 标题 :A process for the synthesis of carbon labeled organic compounds 发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA 权利人:COMMISSARIAT ENERGIE ATOMIQUE 摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.
专利号:US-10913056-B2 优先权日:2017-07-31 标 题:Method for synthesis of copper/copper oxide nanocrystals 发明人:CHEN GUGANG; HARUTYUNYAN AVETIK; RAO YI; LI XIA 权利人:HONDA MOTOR CO LTD; UNIV TEMPLE; TEMPLE UNIV OF THE COMMONWEALTH SYSTEM OF HI 摘要:A simple approach to produce mixed Cu/Cu 2 O nanocrystals having a specific morphology by controlling the reaction temperature during Cu/Cu 2 O nanocrystals synthesis. Other variables are kept constant, such as the amount of reactants, while the reaction temperatures is maintained at a predetermined temperature of 70° C., 30° C. or 0° C., which are used to produce different and controlled morphologies for the Cu/Cu 2 O nanocrystals. The reaction mixture includes a copper ion contributor, a capping agent, a pH adjustor, and reducing agent. The reaction mixture is held at the predetermined temperature for three hours to produce the Cu/Cu 2 O nanocrystals. The synthesis method has advantages such as mass production, easy operation, and high reproducibility.
专利号:US-12162849-B2 优先权日:2018-12-21 标题 :Synthesis of 3-methyl-1,2,4-thiadiazole-5-carbohydrazide or of the methyl-d3 deuterated form thereof 发明人:HOVEYDA HAMID; DUTHEUIL GUILLAUME 权利人:OGEDA SA 摘要:The present invention relates to a method of synthesis of compound (I), wherein R1 represents methyl or methyl-d3, thus corresponding to 3-methyl-1,2,4-thiadiazole-5-carbohydrazide or to the methyl-d3 deuterated form thereof. These compounds are useful as key intermediates in the synthesis of pharmaceutical compounds, especially fezolinetant and deuterated fezolinetant.
专利号:US-7927516-B2 优先权日:2004-09-20 标题 :Method for synthesis of colloidal nanoparticles 发明人:STROUSE GEOFFREY F; GERBEC JEFFREY A; MAGANA DONNY 权利人:UNIV CALIFORNIA 摘要:A method for synthesis of high quality colloidal nanoparticles using comprises a high heating rate process. Irradiation of single mode, high power, microwave is a particularly well suited technique to realize high quality semiconductor nanoparticles. The use of microwave radiation effectively automates the synthesis, and more importantly, permits the use of a continuous flow microwave reactor for commercial preparation of the high quality colloidal nanoparticles.
专利号:US-4598160-A 优先权日:1983-07-15 标题 :Intermediate phenolic compounds for the catalytic synthesis of chromans 发明人:TRUESDALE LARRY K 权利人:HOFFMANN LA ROCHE 摘要:A catalytic synthesis of chromans in racemic or optically active forms, including intermediates thereto; the synthesis employs an asymmetric palladium (II) catalyzed oxidative cyclization of a 2-homoallylphenol and provides intermediates useful in making chromans, especially vitamin E in racemic or optically active forms.
[参考文献]: Diane C Forbes, Et Al. Polymeric Nanocarriers For Sirna Delivery To Murine Macrophages. Macromol Biosci. 2014 Aug;14(8):1096-105. [参考文献]: Fabio Salvatore Palumbo, Et Al. A New Hyaluronic Acid Derivative Obtained From Atom Transfer Radical Polymerization As A Sirna Vector For Cd44 Receptor Tumor Targeting. Macromol Biosci. 2015 Nov;15(11):1605-15. [参考文献]: Haixia Zhou, Et Al. One-Pot Synthesis Of 3,4-Dihydropyrimidin-2(1H)-Ones Using Cubr2 As Catalyst. Prep Biochem Biotechnol. 2006;36(4):375-81. [参考文献]: Hao Yan, Et Al. One-Pot Three-Component Synthesis Of 3-Nitro-2-Arylimidazo[参考文献]: Karthikeyan Kandasamy, Et Al. A Novel Pyrazole Biscoumarin Based Chemosensors For The Selective Detection Of Cu(2+) And Zn(2+) Ions. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Sep 5:148:184-8.
合成参考文献
摘要:Waldvogel, S. R.; Welschoff, N., Science of Synthesis, (2010) 45, 1173. 摘要:Gandon, V.; Malacria, M., Science of Synthesis, (2008) 44, 194. 摘要:Toyota, S., Science of Synthesis, (2010) 45, 864. 摘要:Takeda, T.; Tsubouchi, A., Science of Synthesis Knowledge Updates, (2011) 3, 1. 摘要:Waldvogel, S. R.; Welschoff, N., Science of Synthesis, (2010) 45, 1176.