CAS: 39346-81-1; Agarose

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    专利号:US-5783685-A
    优先权日:1988-12-16
    标题 :Chemical preparation of high specific activity nucleotide probes
    发明人:BAHL CHANDER; MENDOZA LEOPOLDO
    权利人:ORTHO DIAGNOSTIC SYSTEMS INC
    摘要:Methods of chemical synthesis of labeled nucleotide probes are described. The methods comprise providing a first target recognition moiety comprising a nucleotide sequence of at least about 15 nucleotide bases including at least one 5' end and 3' end. The first target recognition moiety is chemically altered to contain a carboxyl group. A second signal generating moiety comprising a hydroxyl group is provided. The carboxyl group of the first target recognition moiety is chemically reacted with hydroxyl group of the second signal generating moiety to chemically join the two moieties and produce said labeled nucleotide probe.

    专利号:US-6608032-B1
    优先权日:1999-01-20
    标题 :Medicinal compositions
    发明人:ENOKI TATSUJI; SAGAWA HIROAKI; TOMONO JUN; TOMINAGA TAKANARI; NISHIYAMA EIJI; WU HUA-KANG; KATO IKUNOSHIN
    权利人:TAKARA SHUZO CO
    摘要:Medicinal compositions for treating or preventing diabetes, rheumatoid, diseases wherein inflammation should be inhibited, diseases wherein alpha-glycosidase should be inhibited, diseases wherein the synthesis of prostaglandin should be inhibited, diseases wherein endotoxin shock should be inhibited, diseases wherein the production of interleukin should be inhibited, diseases wherein the production of heme oxygenase should be induced, and diseases wherein the production of tumor necrosis factor or carcinogenesis should be inhibited, which contain as the active ingredient at least one compound selected from the group consisting of 3,6-anhydrogalactopyranose represented by formula (I), its aldehyde, its hydrate and 2-O-methylated derivatives and 2-O-sulfated derivatives thereof.

    专利号:US-6531148-B1
    优先权日:1998-06-09
    标题 :Therapeutic agents
    发明人:ENOKI TATSUJI; TOMONO JUN; KOYAMA NOBUTO; IKAI KATSUSHIGE; SAGAWA HIROAKI; KATO IKUNOSHIN
    权利人:TAKARA SHUZO CO
    摘要:Therapeutic or preventive agents for diseases requiring apoptosis induction, cancerous diseases, diseases requiring the inhibition of active oxygen production, those requiring the inhibition of nitrogen monoxide production, those requiring the inhibition of prostaglandin synthesis, those requiring the inhibition of synovial cell proliferation, those requiring the induction of heat shock protein production or those requiring the inhibition of α-glycosidase, which contain as the active ingredient compounds selected from among compounds represented by general formula (I), (wherein X and Y are each H or CH 2 OH, provided that when X is CH 2 OH, Y is H, while when X is H, Y is CH 2 OH), those represented by general formula (II), (wherein R is a residue obtained by freeing a compound having an SH group from the SH group) and salts of both; and foods, drinks, cosmetics and so on, containing compounds selected from among compounds of general formula (I), those of general formula (II) and salts of both.

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