CAS: 38444-84-7; 2,3,3'-Trichlorobiphenyl
该化合物是一种属于多氯联苯类的氯化联苯化合物,其特点是联苯结构中存在三氯原子,特别是2欧元,3欧元和3欧元位置;在室温中,该物质一般没有色素,在浅黄色固体中无色,以其疏水性闻名,使其在水中溶解,但在有机溶剂中可溶解;2,3,3,3欧元-三氯联苯的热稳定性和降解耐受性,这助长了其在环境中的持久性;由于其化学稳定性和生物累积潜力,该物质引起了环境和健康问题,特别是其毒性和致癌性;许多国家实施了管制措施,限制多氯联苯的使用和释放,包括2,3,3,3欧元-三氯联苯,因其对人类健康和生态系统的不利影响而导致多氯联苯的使用和释放.
相似化合物
16605-91-7 38444-85-8 41464-39-5MSDS等安全信息
- GHS象形图
- GHS符号GHS08 & GHS09;
注释: Health hazard & Environment - 危险类别特定目标器官毒性-重复接触 类别2
水生急性毒性 类别1
水生慢性毒性 类别1 - 警示词Warning(警告)
- 危险描述H373 |长期或反复接触可能损害器官.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响. - 防范说明P260-P273-P391-P501
- 危险等级9
- UN编号3077.0
- 包装等级Ⅲ
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
欧盟法规
ECHA物质C&L通报上下游产品
3-iod°Chlorobenzene 1,2-Dichloro-3-iodobenzene 1-bromo-2,3-dichlorobenzene 3-chlorophenylboronic acid合成工艺路线路线简述
📜1-氯-3-碘苯,2,3-二氯碘苯置于铜体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应生成2,3,3'-三氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
Doi:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
[参考文献]: D M Fry, Et Al. Effect Of Sediment Contact And Uptake Mechanisms On Accumulation Of Three Chlorinated Hydrocarbons In The Midge, Chironomus Riparius. Bull Environ Contam Toxicol. 1990 May;44(5):790-7.合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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