CAS: 36875-26-0; N-Trifluoroacetyl-D-Glucosamine

该化合物是一种氟化碳水化合物衍生物,广泛用于玻璃化学和药用研究,其主要结构特征--C-2位置的三氟乙酰胺组--增强了稳定性和再活动性,使其对合成玻璃表面和晶体合金很有价值.用电提取的三氟乙酰混合物组有利于选择性的玻璃同步反应,提高产量和立体控制.该化合物是制作生物活性分子,包括玻璃基底抑制剂和代谢研究的标签探测器的多功能中间体.该化合物与标准保护组战略的兼容性进一步突出了其在复杂的寡头树皮化合物组装配中的实用性.研究人员支持这种衍生物在多种合成条件下可以预测的再活动性和稳健性.

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7512-17-6 75251-80-8 5907-41-5

欧盟法规

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上下游产品

ethyl trifluoroacetate, D-(+)-glucosamine hydr°Chloride

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    专利信息


    专利号:US-9951149-B2
    优先权日:2013-06-17
    标 题 :Reversible heparin molecules and methods of making and using the same
    发明人:LIU JIAN; XU YONGMEI; LINHARDT ROBERT J; HARRIS EDWARD
    权利人:UNIV NORTH CAROLINA CHAPEL HILL; RENSSELAER POLYTECH INST; NUTECH VENTURES; RENSSELAER POLYECHNIC INST
    摘要:Methods and systems for synthesizing heparin compounds are provided. The chemoenzymatic synthesis of structurally homogeneous low molecular weight heparins that have a reversible anticoagulant activity is provided. Also disclosed are heparin compounds having anticoagulant activity, including a binding affinity to antithrombin and an anti-Xa activity, but no detectable anti-lla activity. Additionally, provided are synthetic, low-molecular weight heparin compounds with reversible anticoagulant activity, where the anticoagulant activity is reversible by protamine.

    专利号:US-11203772-B2
    优先权日:2010-12-23
    标题:Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins
    发明人:XU YONGMEI; LIU JIAN
    权利人:XU YONGMEI; LIU JIAN; UNIV NORTH CAROLINA CHAPEL HILL
    摘要:Methods for preparing synthetic heparins are provided. Synthetic heparin compounds, including ultralow molecular weight heparin compounds are provided. Also provided are methods of chemoenzymatically synthesizing structurally homogeneous ultra-low molecular weight heparins. Heparin compounds provided herein can have anticoagulant activity.

    专利号:WO-2012088416-A2
    优先权日:2010-12-23
    标 题:Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins

    专利号:US-2013296540-A1
    优先权日:2010-12-23
    标 题 :Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins

    专利号:EP-2655421-A2
    优先权日:2010-12-23
    标 题 :Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins

    专利号:EP-2655421-B1
    优先权日:2010-12-23
    标 题:Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins

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