CAS: 252964-68-4; 1-(Sec-Butyl)-4-(4-(4-(4-Methoxyphenyl)Piperazin-1-yl)Phenyl)-1H-1,2,4-Triazol-5(4H)-One
该化合物是一个合成有机化合物,其特征是复杂的分子结构,包括三联苯环,氟甲津和甲基氧基联苯组.这种复合物展示了典型的三联苯衍生物特性,如潜在的抗风化和抗微生物活动,因为三联苯功能组因其与生物目标相互作用的能力而闻名.管状体环有助于其药理学特征,经常提高溶性性和生物利用率.此外,甲氧基组可能影响化合物的脂性以及总体生物活动.异丙基体组的存在进一步改变其与生物系统的互动.
- 英文名称1-(Sec-Butyl)-4-(4-(4-(4-Methoxyphenyl)Piperazin-1-yl)Phenyl)-1H-1,2,4-Triazol-5(4H)-One
- 中文名称2,4-二氢-4-[4-[4-(4-甲氧基苯基)-1-哌嗪基]苯基]-2-(1-甲基丙基)-3H-1,2,4-三唑-3-酮
- IUPAC名称2-(sec-butyl)-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
- 其它别名3H-1,2,4-Triazol-3-One, 2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)-1-Piperazinyl]Phenyl]-2-(1-Methylpropyl)-; 2-Sec-Butyl-4-(4-[4-(4-Methyloxy-Phenyl)-Piperazin-1-Yl]-Phenyl)-2,4-Dihydro-[1,2,4]-Triazol-3-One; 2-Butan-2-Yl-4-[4-[4-(4-Methoxyphenyl)Piperazin-1-Yl]Phenyl]-1,2,4-Triazol-3-One; 1-Sec Butyl-[4[4(4-Methoxyphenyl)-1-Piperazinyl]-Phenyl]-1,2,4-Triazolo-5-One; 2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)-1-Piperazinyl]Phenyl]-2-(1-Methylpropyl)-3H-1,2,4-Triazol-3-One; 2,4-Dihydro-4-[[4-Hydroxyphenyl]-1-Piperazinyl] 98.50+% Light Gray Powder; 3H-1,2,4-Triazol-3-One,2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)-1-; 2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)-1-Piperazinyl]
- CAS编号252964-68-4
- MFCD编号:MFCD02956607
- EINECS号:607-685-0
- FDA UNII编号:148K9U451A
- 分子式:C23H29N5O2分子量:407.52
- 产品CID: 1212268
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
物理性质
MSDS等安全信息
欧盟法规
REACH注册ECHA物质C&L通报REACH预注册上下游产品
CAS号74853-06-8 4-([4-(4-甲氧基-苯基... | CAS号106461-41-0 2,4-二氢-4-[[4-(4...合成工艺路线路线简述
📜1-(4-甲氧基苯基)哌嗪置于palladium 10% On Activated Carbon 吡啶,甲酸铵,Potassium Carbonate,1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 甲醇,二氯甲烷,二甲基亚砜,甲苯 用作溶剂,化学反应 20.5H,反应生成2,4-二氢-4-[4-[4-(4-甲氧基苯基)-1-哌嗪基]苯基]-2-(1-甲基丙基)-3H-1,2,4-三唑-3-酮
参考文献:Wo2008/124132
标题:Wo2008/124132
海关参考信息
- 2905110000-甲醇
2921211000-乙二胺
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/j.bbrc.2023.08.050
摘要:Ikeda Y, Davis MI, Sumita K, Zheng Y, Kofuji S, Sasaki M, Hirota Y, Pragani R, Shen M, Boxer MB, Takeuchi K, Senda T, Simeonov A, Sasaki AT. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells. Biochemical and Biophysical Research Communications. 2023 Oct;679():116–21. doi: 10.1016/j.bbrc.2023.08.050.
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