CAS: 23860-35-7; 2-Cyclohexylacetyl Chloride

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CAS号5292-21-7 环己基乙酸 | CAS号79-37-8 草酰氯 | CAS号5452-75-5 环已乙酸乙酯 | CAS号103-82-2 苯乙酸 | CAS号4709-59-5 1-Cyclohexene-1... | CAS号457-49-8 CYCLOHEXYLTRIFL... | CAS号42716-73-4 alpha-溴环己烷乙酸乙酯 | CAS号4435-14-7 1-环己基乙腈 | CAS号4442-79-9 2-环己基乙醇 | CAS号5664-21-1 环己基乙醛 | CAS号64127-44-2 4-环己基-3-氧代丁酸乙酯 | CAS号5292-21-7 环己基乙酸 | CAS号103-78-6 环己基丙酮 | CAS号149108-75-8 CYCLOHEXYLMETHY... | CAS号110-83-8 环己烯

📜环己基乙酸置于草酰氯体系中,用 二氯甲烷,N,N-二甲基甲酰胺 用作溶剂,化学反应生成环己基乙酰氯
参考文献:通过有机光氧化还原催化的氢原子转移作用,酰胺的伯,仲和叔γ-C(sp 3)-H乙烯基化
标题:通过有机光氧化还原催化的氢原子转移作用,酰胺的伯,仲和叔γ-C(sp 3)-H乙烯基化
摘要:据报道,用烯基硼酸对酰胺的伯,仲和叔脂族γ-C(sp 3)-H进行乙烯基化的有效策略.这些反应由可见光有机光氧化还原剂催化.酰胺的区域选择性γ-C(sp 3)-h乙烯基化是由就地生成的mid基的1,5-氢原子转移控制的.
Doi:10.1021/acs.Orglett.8B02737

专利信息

专利号:US-3959322-A
优先权日:1960-09-22
标 题:Synthesis of 13-alkyl-gon-4-ones
发明人：HUGHES GORDON ALAN; SMITH HERCHEL
权利人:SMITH HERCHEL
摘要:The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.

专利号:US-5194671-A
优先权日:1991-05-23
标题 :Process for the preparation of β-ketocarboxylic acid esters
发明人：MEIER JOSEF
权利人:WACKER CHEMIE GMBH
摘要:The invention relates to a process for the preparation of β-ketocarboxylic acid esters of the general formula ##STR1## in which R 1 is an alkyl radical having 1 to 4 C atoms, R 2 is an alkyl radical or alkenyl radical having 2 to 15 C atoms or a phenyl radical and R 3 is hydrogen or an alkyl or alkenyl radical having 1 to 6 C atoms, characterized in that acetocarboxylic acid esters of the general formula ##STR2## in which R 1 and R 3 are as defined, are reacted with calcium hydroxide or calcium oxide in the presence of an organic solvent and in the absence of water, the calcium chelate complexes formed are acylated with carboxylic acid chloride and the products are then cleaved with aqueous ammonium salt solution to form the β-ketocarboxylic acid esters of formula (I). n The β-ketocarboxylic acid esters readily accessible by the process according to the invention can be used as important intermediates in the synthesis of pharmaceutically active ingredients or plant protection agents.

专利号:WO-2010115869-A1
优先权日:2009-04-03
标 题 :Propofol phosphonyl derivatives, synthesis, and use in long acting formulations
发明人：GONNISSEN YVES RENE JOHANNA PAUL
权利人:SEPS PHARMA N V; GONNISSEN YVES RENE JOHANNA PAUL
摘要:This invention relates to compounds represented by the structural formula (I), and the salts and stereoisomers thereof, wherein: - L is a linker selected from the group consisting of -(CH 2 ) P -O-, a single bond, formula (IA), -(CH 2 ) 1-8 -O-X(O)-, and - p is an integer from 1 to 8, - each R 3 and each R 4 is independently selected from the group consisting of C 1-20 alkyl, C 3-12 alkyl, C 3-12 cycloalkyl-C 1-4 alkyl, saturated heterocyclyl and saturated heterocyclyl-C 1-4 alkyl, and - X and Y are each independently C or S(O), - Z is selected from the group consisting of O, S(O) and NR 5 , - W is selected from the group consisting of halogen, OH, S(O)H and O - M + wherein M + is a monovalent cation; and - R 5 is selected from the group consisting of hydrogen and C 1-10 alkyl. These compounds are useful pharmaceutical agents with improved oral bioavailability.

专利号:US-3636119-A
优先权日:1969-10-20
标题:4-amino-2-(8-cyclohexyloctyl or 7-cyclohexylheptyl)-1-naphthol
发明人：FIESER LOUIS F; LORENZ ROMAN R; ARCHER SYDNEY
权利人:FIESER LOUIS F; ROMAN R LORENZ; SYDNEY ARCHER
摘要:4-AMINO-2-Q-1 NAPHTHOL COMPOUNDS WHICH ARE USEFUL AS INTERMEDIATES IN THE SYNTHESIS OF 2-Q-1,4-NAPHTHOQUINONE COMPOUNDS, WHERE Q IS (7-CYCLOHEXYLHEPTYL OR 8-CYCLOHEXYLOCTYL).

专利号:US-4160862-A
优先权日:1972-06-12
标 题 :1-Acyl-3-(amino-lower-alkyl)indoles
发明人：ZENITZ BERNARD L
权利人:STERLING DRUG INC
摘要:1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.

专利号:US-4021431-A
优先权日:1972-06-12
标 题:3-(Piperidino-lower-alkyl)-indoles
发明人：ZENITZ BERNARD L
权利人:STERLING DRUG INC
摘要:1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.