专利号:WO-2023102600-A1 优先权日:2021-12-06 标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom 发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI 权利人:NEWSOUTH INNOVATIONS PTY LTD 摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.
专利号:WO-2017051326-A1 优先权日:2015-09-23 标 题 :New processes and intermediates useful in synthesis of nep inhibitors 发明人:MARTIN BENJAMIN; PENN GERHARD; SCHENKEL BERTHOLD; BOURNE SAMUEL; LAU SHING-HING; LEY Steven 权利人:NOVARTIS AG; MARTIN BENJAMIN; PENN GERHARD; SCHENKEL BERTHOLD; BOURNE SAMUEL; LAU SHING-HING; LEY Steven 摘要:The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors such as sacubitril, and prodrugs thereof.
专利号:US-10717718-B2 优先权日:2015-11-17 标 题:5-azido-5-deoxy-2 :3-isopropylidene-D-arabinose compounds; their method of manufacture and their use for the synthesis of ARA-N3, KDO-N3 and 4EKDO-N3 发明人:VAUZEILLES BORIS; MAS PONS JORDI; BARON AURÈLIE 权利人:CENTRE NAT RECH SCIENT 摘要:Disclosed are new compounds of formulae: n nWherein: R 1 and R 2 can be independently H; a C 1 to C 6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R 1 ,R 2 together with the carbon C-6 can be a cyclopentylidene or cyclohexylidene; each of these groups being substituted or not; and R 3 can be a C 1 to C 6 alkyl including methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl; or aryl including phenyl, methylphenyl, ethylphenyl, each of these groups being substituted or not. The invention also relates to their method of manufacture and their use for the synthesis of Ara-N 3 , Kdo-N 3 and 4eKdo-N 3 .
专利号:US-2006079719-A1 优先权日:2002-04-16 标 题 :Aminated compounds bearing at least an allyl and a difluoromethyl and method used for synthesis thereof 发明人:BONNET-DELPON DANIELE; BEGUE JEAN-PIERRE; LEGROS JULIEN; CROUSSE BENOIT; MEYER FRANCK 权利人:BONNET-DELPON DANIELE; BEGUE JEAN-PIERRE; LEGROS JULIEN; CROUSSE BENOIT; MEYER FRANCK 摘要:The invention relates to aminated compounds bearing at least an allyl and a difluoromethyl and a method used for synthesis thereof. Said compounds comprise at least one carbon bearing: an amine function, an allyl or propargyl radical, a difluoromethylene group, and a hydrogen or a hydrocarbon radical, advantageously selected among those which are electron donors or hardly electroattractive (; 0. 1). The invention is useful for synthesis of fluorinated compounds.
专利号:US-9150498-B2 优先权日:2011-10-25 标题:Process for the preparation of oseltamivir and methyl 3-epi-shikimate 发明人:RAWAT VARUN; DEY SOUMEN; ARUMUGAM SUDALAI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention discloses high yielding enantioselective process for synthesis of Oseltamivir from readily available starting material, cis-1,4-butene diol. The process features incorporation of chirality using sharpless asymmetric epoxidation (AE) and diastereoselective Barbier allylation and construction of cyclohexene carboxylic acid ester core through a ring closing metathesis (RCM) reaction. Further also disclosed herein is synthesis of (−)-methyl 3-epi-shikimate.
专利号:US-2023212107-A1 优先权日:2021-12-30 标 题:Synthesis of para-alkylated syringyl (meth)acrylate derivatives and photopolymerizable compositions for additive manufacturing in dental applications 发明人:CHOUDHARY UMESH UPENDRA; SU JESSICA KALAY 权利人:ALIGN TECHNOLOGY INC 摘要:The present disclosure provides polymerizable monomers which may be used as reactive diluents in additive manufacturing. The polymerizable monomers may have low vapor pressures and may be compatible with a range of low glass transition temperature oligomers.
参考标题:Synthesis Of 1‐(3 H )Isobenzofuranone Compounds By Tin Powder Promoted Cascade Condensation Reaction 作者:Shangxian Wang,Ke‐hu Wang,Bo Chang,Danfeng Huang,Yulai Hu |发布日期:2021.7 摘要:An Efficient Approach For The Construction Of Phthalide Compounds Is Developed Through Tin Powder Mediated Cascade Condensation Reaction Of 2-Formylbenzoic Acids With Allyl Bromides Or α-Bromoketone Under Mild Reaction Conditions. This Method Is Easy To Operate And Can Tolerate Various Functional Groups To Give The Corresponding Phthalides In Good To Excellent Yields. The Phthalides Produced From α-Bromoketone
合成参考文献
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