CAS: 14092-00-3; Methyl(O-Tolyl)Sulfane

该化合物是一种含有硫的芳香化合物,含有分子式C8H10S.这种甲苯衍生物在正方形上具有甲基硫烷基组,在有机合成中具有独特的再活性.其结构使它成为制备药品,农用化学品和特殊化学品的宝贵中间体.该化合物在普通有机溶剂中表现出适度的稳定性和溶性,便于其在各种反应中使用,包括电益替代物和金属催化联变.其独特的电子特性也使其在离子体设计和材料科学应用中有用.建议在惰性条件下进行适当处理,因为可能对氧化具有敏感性.

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4163-79-5 66623-67-4 34678-67-6

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上下游产品

dimethyl sulfate 2-thi°Cresol thiophenol methyl iodide 4-(3-methyl-4-methylsulfanyl-phenyl)-4-oxo-butyric acid N-(2-methylphenylthio)succinimide methyl 4-bromo-2-methylphenyl sulphide 1-methyl-2-(methylsulfonyl)benzene

合成工艺路线路线简述

    📜Bis-<2-(Methylthio)Benzyl> Oxalate 以3%的收率获得
    参考文献:Cadogan,J. I. G.;Husband,J. B.;Mcnab,H.,J. Chem. Soc. Perkin Trans.,1983,N 5,697-701
    标题:Cadogan,J. I. G.;Husband,J. B.;Mcnab,H.,J. Chem. Soc. Perkin Trans.,1983,N 5,697-701

    海关参考信息

    专利信息


    专利号:US-8367871-B2
    优先权日:2007-03-09
    标 题 :Process for production of optically active sulfoxide compound using iron-salan complex catalyst
    发明人:KATSUKI TSUTOMU; EGAMI HIROMICHI
    权利人:NISSAN CHEMICAL IND LTD; KATSUKI TSUTOMU; EGAMI HIROMICHI
    摘要:An optically active sulfoxide compound that is useful as an intermediate for synthesis or an active ingredient of a physiologically active substance such as a pharmaceutical agent is produced at a high optical purity. A process for producing an optically active sulfoxide compound of formula (4) comprises oxidizing a sulfide compound of formula (3) in the presence of an optically active metal complex of formula (1), (1′), (2) or (2′) by using an oxidizing agent. The present invention is also directed to the optically active metal complex.

    专利号:US-9555039-B2
    优先权日:2011-05-09
    标题:Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)

    专利号:CN-109796475-A
    优先权日:2018-12-27
    标题 :A kind of simple synthesis of resisting virus, eliminating inflammation medicine Etoricoxib important intermediate to methylthiobenzyl magnesium chloride

    专利号:US-9169209-B2
    优先权日:2011-05-04
    标题:Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and composition for inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:CN-109651272-A
    优先权日:2018-12-27
    标题 :A kind of easy synthesis technology of Quazepam intermediate

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Lattanzi, A., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 1002.
    摘要:Lattanzi, A., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 1006.
    摘要:Zhang, C.; Duan, Y.-N., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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