CAS: 136370-19-9; 4-Heptyloxyphenylboronic Acid

该化合物是一种有机有机体化合物,其特征是,一种附于一个苯环的碳酸功能组,该物质组又被一个七环组所取代,该化合物通常具有中溶性,水溶性有限等特性,这在烷基替代碳酸中是常见的;七环氧组增强了其疏水特性,使其在各种有机合成应用中有用,特别是在材料和药品的开发中. 溴酸混合物允许与二醇进行可逆共价结合,使其在感测应用和形成黄酸酯中具有价值. 此外,该化合物还可参与铃木混合反应,这是形成碳结结的有机化学的一种关键方法.该化合物的结构特征有助于其在有机电子,药物运载系统和作为更复杂的分子合成中的一个构件块的潜在用途.

结构式图片

相似化合物

121554-09-4 121219-08-7 146449-90-3

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4-n-heptyloxybromobenzene 4-bromo-phenol 3-(4-Heptyloxy-phenyl)-cyclohex-2-enone 1,4-bis(4-heptyloxyphenyl)-6,7-dimethylanthraquinone 1,4-bis(4-heptyloxyphenyl)anthraquinone 4-nitro-4'-heptoxybiphenyl

合成工艺路线路线简述

    📜4-正庚氧基溴苯置于正丁基锂,盐酸体系中,用 四氢呋喃 用作溶剂,化学反应生成4-庚氧基苯硼酸
    参考文献:Arylation Of Chloroanthraquinones By Surprisingly Facile Suzuki-miyaura Cross-Coupling Reactions
    标题:Arylation Of Chloroanthraquinones By Surprisingly Facile Suzuki-miyaura Cross-Coupling Reactions
    摘要:研究发现,使用商用催化剂 Pd(Pph3)4 以及由 Pd(Pph3)2Cl2 和 Pph3 原位制备的 Pd(Pph3)4,氯蒽醌可与取代的苯基硼酸发生简单的铃木交叉偶联.
    Doi:10.3184/030823409X12586584303880

    海关参考信息

    专利信息


    专利号:US-9795613-B2
    优先权日:2014-12-10
    标题 :GLP-1 receptor modulators
    发明人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL; GLYNN DANIEL; MILLS MARK
    权利人:CELGENE INT II SÀRL
    摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.

    专利号:US-9187522-B2
    优先权日:2011-12-12
    标题 :GLP-1 receptor modulators
    发明人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL
    权利人:RECEPTOS INC
    摘要:The invention relates to compounds that modulate the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds are act as modulators or potentiators of GLP-1 receptor on their own, or with receptor ligands including GLP-1 peptides GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.

    专利号:US-9598430-B2
    优先权日:2013-06-11
    标 题 :GLP-1 receptor modulators
    发明人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL
    权利人:RECEPTOS INC; CELGENE INT II SÀRL
    摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.

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