📜3-(1H-Benzo[d][1,2,3]Triazol-1-yl)-1,3-Diphenylpropan-1-One置于六甲基磷酰三胺,Samarium Diiodide体系中,用 四氢呋喃 用作溶剂,化学反应 0.17H,以100%的收率获得ω-苄基苯乙酮 参考文献:Diastereoselective Synthesis Of Cis-1,2-Disubstituted Cyclopropanols And Cyclopent-3-Enols Via Smi2 Mediated C-n(Bt) Bond Cleavage 标题:Diastereoselective Synthesis Of Cis-1,2-Disubstituted Cyclopropanols And Cyclopent-3-Enols Via Smi2 Mediated C-n(Bt) Bond Cleavage 摘要:Diastereoselective Synthesis Of Cis-1,2-Disubstituted Cyclopropanols And Cyclopent-3-Enols Has Been Achieved From Readily Available Beta-Benzotriazolyl Ketones (Beta-Bt Ketones) Via A C-N(Bt) Bond Cleavage/cyclization Process Promoted By Smi2/hmpa. (C) 2015 Elsevier Ltd. All Rights Reserved. Doi:10.1016/j.Tetlet.2015.05.002
专利信息
专利号:US-11161827-B2 优先权日:2019-04-05 标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination 发明人:Zhang xiao-xiang; Lang kai 权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE 摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
专利号:US-10981850-B2 优先权日:2019-04-15 标 题 :One-step flow-mediated synthesis of cannabidiol (CBD) and derivatives 发明人:PORCO JOHN A; BEELER AARON B; BROWN LAUREN E; TRILLES RICHARD V 权利人:UNIV BOSTON 摘要:Herein are described apparatus and processes for the preparation of cannabinoids, such as cannabidiol (CBD) and derivatives thereof. The apparatus and processes described can be used for the one-step, flow-mediated synthesis of cannabidiol and derivatives with improved overall yield, material throughput, and product purity relative to batch processes.
专利号:US-2017204442-A1 优先权日:2014-05-29 标题 :Enzymatic synthesis of soluble glucan fiber 发明人:DICOSIMO ROBERT; CHENG QIONG; ELIOT ANDREW C; OUWEHAND ARTHUR; PAYNE MARK S; YOU ZHENG 权利人:DU PONT 摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
专利号:US-5084147-A 优先权日:1988-01-08 标 题 :Process of synthesis of organic substances by an indirect electrochemical route with a redox system in the solid state 发明人:BIANCHI GIUSEPPE; VALSECCHI FRANCO; BUREI GIOVANNI 权利人:BIANCHI GIUSEPPE; VALSECCHI FRANCO; ENICHEM SINTESI 摘要:A process of oxidation or reduction of organic substrates by an indirect electrochemical route is described. During oxidation, the electrochemical stage produces a metallic oxide having higher valence such as RuO 2 , NiOOH, which is applied to an inert conductor support. The supported metallic oxide of higher valence is separated from the aqueous electrolyte and is then placed in contact with the pure organic material to be reacted on. The metallic oxide in this manner is reduced to a lower valence and is subjected to a new electrochemical oxidation after the residues of the organic material are removed. The process consists of a cyclic repetition of these stages. The process of reduction of organic substrates is analogous and is carried out by means of the hydrogen of hydrides formed through a cathodic charge by electrolysis of an aqueous solution.
专利号:US-8212056-B2 优先权日:2008-06-30 标 题 :Ligands for transition-metals and methods of use 发明人:KWONG FUK YEE; SO CHAU MING 权利人:KWONG FUK YEE; SO CHAU MING; UNIV HONG KONG POLYTECHNIC 摘要:The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture.
专利号:US-10907185-B2 优先权日:2014-05-29 标 题 :Enzymatic synthesis of soluble glucan fiber 发明人:CHENG QIONG; DICOSIMO ROBERT; OUWEHAND ARTHUR; YOU ZHENG; LAI JIAN PING; YU ZHEYONG; ZHANG ZHENGHONG 权利人:DUPONT IND BIOSCIENCES USA LLC 摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
参考文献:10.4103/0971-4065.82131 摘要:Boutabet K, Kebsa W, Alyane M, Lahouel M. Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin. Indian J Nephrol. 2011 Apr;21(2):101–6.