CAS: 106-96-7; 3-Bromopropyne

上下游产品

CAS号107-19-7 丙炔醇 | CAS号867-13-0 磷酰基乙酸三乙酯 | CAS号16156-58-4 甲磺酸-2-丙炔-1-醇 | CAS号61939-85-3 N-(2,6-dibromop... | CAS号61939-88-6 2-[N-propargyl-... | CAS号61939-89-7 2-[N-propargyl-... | CAS号61939-90-0 N-(2,6-diethylp... | CAS号61939-91-1 N-(3-methoxyphe... | CAS号61939-92-2 (2-chloro-4-met... | CAS号61939-93-3 (2-chloro-6-met... | CAS号107428-06-8 2-烯丙基-2-(2-丙炔-1... | CAS号108164-63-2 trimethyl((1-ph... | CAS号108164-62-1 trimethyl(1-phe... | CAS号109964-28-5 ethyl 4-°Ctyl-4... | CAS号105279-32-1 6-methyl-4-prop... | CAS号105729-54-2 3,6-dibromo-9-p... | CAS号104501-02-2 1H-Pyrrole-2-ca... | CAS号109317-93-3 5-(1-phenylbut-... | CAS号10575-06-1 but-3-ynylsulfa... | CAS号108521-58-0 prop-2-ynyl 2-i...

甲磺酸-2-丙炔-1-醇置于magnesium Bromide体系中,用 乙醚 用作溶剂,化学反应 1.0H,反应生成3-溴丙炔
参考文献:Synthése D'Alcools α-Alléniques Par Réaction D'Organochromiques Propargyliques Sur Les Aldéhydes Et Les Cétones
标题:Synthése D'Alcools α-Alléniques Par Réaction D'Organochromiques Propargyliques Sur Les Aldéhydes Et Les Cétones
摘要:
Doi:10.1016/s0040-4020(01)92452-4

专利信息

专利号:US-6504041-B2
优先权日:1996-11-15
标题 :Synthesis of ruthenium or osmium metathesis catalysts
发明人：GRUBBS ROBERT H; BELDERRAIN TOMAS R; BROWN SETH N; WILHELM THOMAS E
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention relates to the synthesis of highly active ruthenium and osmium carbene metathesis catalyst in good yield from readily available starting materials. The catalysts that may be synthesized are of the general formula n wherein: n M is ruthenium or osmium; n X and X 1 are independently any anionic ligand; n L and L 1 are any neutral electron donor ligand; and, n R and R 1 are each hydrogen or one of the following substituent groups: C 2 -C 20 alkenyl, C 2 -C 20 alkynyl, C 1 -C 20 alkyl, aryl, C 1 -C 20 carboxylate, C 1 -C 20 alkoxy, C 2 -C 20 alkenyloxy, C 2 -C 20 alkynyloxy, aryloxy, C 2 -C 20 alkoxycarbonyl, C 1 -C 20 alkylthio, C 1 -C 20 alkylsulfonyl and C 1 -C 20 alkylsulfinyl. Optionally, the substituent group may be substituted with one or more groups selected from C 1 -C 5 alkyl, halogen, C 1 -C 5 alkoxy, and aryl. When the substitute aryl group is phenyl, it may be further substituted with one or more groups selected from a halogen, a C 1 -C 5 alkyl, or a C 1 -C 5 alkoxy. Specific synthetic protocols for vinyl alkylidene catalysts wherein R is hydrogen and R 1 is —CHCR 12 R 13 and non-vinyl alkylidene catalysts are also disclosed. In addition to the ease of synthesis (typically a one-step synthesis), the reactions generally may be run at or above room temperature and the resulting products usually may be used without extensive post synthesis purification.

专利号:US-11427596-B2
优先权日:2019-07-19
标 题:Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications
发明人：CHELVAM VENKATESH; DUDHE PREMANSH; KRISHNAN MENA ASHA; SONAWANE AVINASH
权利人:INDIAN INSTITUTE OF TECH INDORE
摘要:Embodiments herein provide fused-pyrido heterocycles such as azaindoles, carboline derivatives, furo[b]pyridines or furo[b]pyridine-isatin hybrids of Formula I.Embodiments also relate to a process for a synthesis of variety of complex pyrido-heterocycles The pyrido-heterocycles can be used for treating cancer (cervix, kidney, lung, breast and epidermal skin) and multi-drug resistant tuberculosis. These heterocycles can also be used as anti-biofilm agents against pathogenic strains, which will minimize the risk of secondary infections.

专利号:US-11945838-B2
优先权日:2018-12-20
标 题:Method for synthesis of protein amphiphiles
发明人：BRITTO Sandanaraj Selvaraj; REDDY Mullapudi Mohan
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES
摘要:The present invention discloses a novel cost effective method for synthesis of protein/peptide amphiphiles irrespective of functional and structural classification of proteins useful in designing a vaccine candidate from antigenic protein. The protein modification of the present invention is universal and hence any protein/peptide can be converted into amphiphilic proteins/peptides.

专利号:US-6376676-B1
优先权日:1993-06-30
标题 :Intermediates in the synthesis of (±)-camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; LIU HUI
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of novel intermediates in the synthesis of (±)-camptothecin and related compounds. The present synthesis scheme includes a novel 4+1 radical annulation followed by another cyclization to simultaneously assemble rings B and C of the camptothecin compound. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-6252079-B1
优先权日:1993-06-30
标 题 :Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; BOM DAVID
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of irinotecan and derivative compounds which comprises of a novel 4+1 radical annulation wherein the precursoris reacted with an aryl isonitrile having the formulawherein X is Br or I, and R4 is an alkyl group, an allyl group, a propargyl group or a benzyl group, and R16 is H, a C1-C6 alkoxy group, agroup wherein p is an integer between 4 and 12, or a C1-C12 acyclic dialkylamino group. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-8901352-B2
优先权日:2011-01-13
标题 :Method for the synthesis of rasagiline
发明人：REIS ÖMER; KOYUNCU HASAN; ESIRINGU ILKER; SAHIN YASEMIN; GULCAN H OZAN
权利人:REIS ÖMER; KOYUNCU HASAN; ESIRINGU ILKER; SAHIN YASEMIN; GULCAN H OZAN; NOBEL ILAÇ SANAYII VE TICARET A S
摘要:We have developed a new method for the synthesis of Rasagiline (Formula 1) based on the alkylation of trifluoroacetyl protected aminoindan. This protection enabled us to carry out an alkylation of aminoindan with a high yield and purity under very mild conditions with a wide range of reaction conditions and reagent selection. Considering the ease, purity and high yields of introducing and removal of the trifluoroacetyl group, this approach is a highly practical and economical way for the synthesis of rasagiline or its pharmaceutically acceptable salts.