Dl-扁桃酸甲酯置于sodium Hydroxide,(Nme4)*2H2O*ch3Cn (L = Ortho-Phenylenebis(N'-Methyloxamidate)),氧气,特戊醛,Lithium Diisopropyl Amide体系中,用 乙腈 作为反应溶剂,化学反应 2.0H,反应生成 环己基苯基甲酮 参考文献:Catalytic Aerobic Oxidative Decarboxylation Of α-Hydroxy-Acids. Methyl Mandelate As A Benzoyl Anion Equivalent 标题:Catalytic Aerobic Oxidative Decarboxylation Of α-Hydroxy-Acids. Methyl Mandelate As A Benzoyl Anion Equivalent 摘要:The Monomeric Square-Planar Cobalt(Iii) Complex Of Bis-N,N'-Disubstituted Oxamides Catalyses The Oxidative Decarboxylation Of Alpha-Hydroxy Acids With Molecular Oxygen/pivalaldehyde With Very Good Yields. This Reaction Offers An Interesting Alternative In The Use Of Methyl Mandelate As A Convenient Benzoyl Anion Equivalent. (C) 1998 Elsevier Science Ltd. All Rights Reserved. DOI:10.1016/s0040-4039(98)00482-1
专利号:US-6825378-B2 优先权日:2003-03-28 标 题 :Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid 发明人:KUMAR PRADEEP; FERNANDES RODNEY AGUSTINHO; GUPTA PRITI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides a process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid of formula (1). The present invention more particularly relates to a process using cyclohexylphenyl ketone for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid of formula (1).
专利号:US-7435861-B2 优先权日:2005-04-29 标 题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates 发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID 权利人:CARDAX PHARMACEUTICALS INC 摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.
专利号:US-2008221377-A1 优先权日:2006-06-16 标题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates 发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L 权利人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L 摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.
专利号:US-10487099-B2 优先权日:2017-06-30 标 题:Synthesis of hypervalent iodine reagents with dioxygen 发明人:POWERS DAVID CHARLES; MAITY ASIM; HYUN SUNG-MIN 权利人:TEXAS A & M UNIV SYS 摘要:Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.
专利号:WO-9856796-A1 优先权日:1997-06-09 标题 :Delivery and scavenging agents for combinatorial synthesis 发明人:BOUSSIE THOMAS; HALL KEITH A; LAPOINTE ANNE M; MURPHY VINCE; POWERS TIMOTHY; BEEK JOHANNES A M VAN 权利人:SYMYX TECHNOLOGIES INC 摘要:Delivery and scavenging agents are provided for the combinatorial synthesis of organometallic compounds in a solution or suspension, where the agents are constructed from a solid support allowing for easy separation of unreacted reagents or unwanted materials from a synthesis reaction. Use of these solid supported agents also allows otherwise unfavorable reactions to be driven to completion by the use of large excesses of reactants and minimizes the chances for competing bimolecular side reactions in parallel or rapid serial synthesis.
专利号:US-4980428-A 优先权日:1989-10-20 标 题 :Epoxy vinyl ethers and synthesis of an epoxy vinyl ether from a hydroxylated vinyl ether and a polyepoxide 发明人:LIU KOU-CHANG; VARA FULVIO J; DOUGHERTY JAMES A 权利人:GAF CHEMICALS CORP 摘要:This invention relates to epoxy vinyl ethers having the formula: ##STR1## wherein R is a polyvalent linear, branched or cyclic hydrocarbon radical having from 2 to 20 carbon atoms, optionally substituted with alkylenoxy; n has a value of from 1 to 20; p has a value of from 1 to 6; and at least one of Y and Y' is ##STR2## which any remaining Y and Y' can be ##STR3## The invention also relates to the synthesis and uses of the above polyphenyl vinyl ethers.