CAS: 637328-69-9; Tanogitran

📜(R)-2-(4-Amidinophenylaminomethyl)-1-Methyl-5-[1-(Ethyloxycarbonylmethylamino)-1-(Pyrrolidinocarbonyl)-Ethyl]-Benzimidazole-P-Toluenesulphonic Acid Salt置于氢氧化钾,对甲苯磺酸体系中,用 甲醇 作为反应溶剂,化学反应 2.5H,以85%的收率获得产物tanogitran; N-[(1R)-1-[2-[[(4-甲脒基苯基)氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]-1-甲基-2-氧代-2-(1-吡咯烷基)乙基]甘氨酸
参考文献:(R) 2-(4-Amidinophenylaminomethyl)-1-Methyl-5-[1-(Carboxymethylamino)-1 (Pyrrolidinocarbonyl)-Ethyl]-Benzimidazole,The Monohydrochloride Thereof,Preparation Thereof And The Use As Pharmaceutical Composition
标题:(R) 2-(4-Amidinophenylaminomethyl)-1-Methyl-5-[1-(Carboxymethylamino)-1 (Pyrrolidinocarbonyl)-Ethyl]-Benzimidazole,The Monohydrochloride Thereof,Preparation Thereof And The Use As Pharmaceutical Composition
摘要:(R)-2-(4-氨基苯胺甲基)-1-甲基-5-[1-(羧甲基氨基)-1-(吡咯烷基甲酰基)乙基]-苯并咪唑及其单盐酸盐的晶体形式,其制备方法以及用作药物组成物的用途.