CAS: 619-66-9; 4-Formylbenzoic Acid

上下游产品

CAS号623-27-8 对苯二甲醛 | CAS号106-42-3 对二甲苯 | CAS号124-38-9 二氧化碳 | CAS号128376-65-8 4-(5,5-二甲基-1,3,... | CAS号24856-58-4 4-溴苯甲醛二甲基缩醛 | CAS号64-19-7 冰醋酸 | CAS号99-94-5 对甲基苯甲酸 | CAS号56-91-7 氨甲苯酸 | CAS号15164-44-0 4-碘苯甲醛 | CAS号111616-43-4 Benzaldehyde, 4... | CAS号106315-48-4 4-[3-(4-cyanoph... | CAS号3006-96-0 4-羟甲基苯甲酸 | CAS号110137-64-9 4-(anilinomethy... | CAS号34040-64-7 4-氯甲基苯甲酸甲酯 | CAS号307510-92-5 5-[(4-羧基苯基)亚甲基]... | CAS号42228-16-0 甲基4-甲酰苯甲酸酯二缩醛 | CAS号1571-08-0 对甲酰基苯甲酸甲酯 | CAS号38628-51-2 4-(2-羧乙基)苯甲酸 | CAS号143412-99-1 4-[(3-oxo-1H-in...

对二甲苯置于air,Copper Diacetate,Cobalt(II) Acetate,溶剂黄146,Sodium Bromide体系中,150.0 °C,4.05 Mpa 条件下,反应 2.0H,反应生成 对醛基苯甲酸
参考文献:钴-铜-溴化物体系液相氧化甲基苯
标题:钴-铜-溴化物体系液相氧化甲基苯
摘要:由乙酸钴(II)和乙酸铜(II)和溴化钠组成的催化剂体系催化甲基苯的液相氧化,在乙酸中于 150 oc 下进行.在大多数情况下,以高选择性获得相应的乙酸苄酯和苯甲醛.在对甲氧基甲苯的氧化中也得到核溴化产物,即3-溴-4-甲氧基甲苯,其具有两个不同的反应位点,即供电子甲氧基取代基的邻位和苄基位.然而,在催化剂体系中溴离子取代乙酸根离子对侧链氧化产物具有令人满意的选择性.在对二甲苯氧化中,还得到了α,α'-二乙酰氧基-对二甲苯和对(乙酰氧基甲基)苯甲酸,以及对甲基乙酸苄酯,虽然他们的金额很小.还进行了多甲基苯的氧化.
DOI:10.1246/bcsj.54.2724

专利信息

专利号:US-6251689-B1
优先权日:1998-05-14
标 题:Methods for the solid phase synthesis of combinatorial libraries of benzimidazoles benzoxazoles benzothiazoles and derivatives thereof
发明人：LABORDE EDGARDO; MATSUMOTO YUKIHARU
权利人:TELIK INC
摘要:The present invention provides an efficient and versatile method for the synthesis and screening of combinatorial libraries of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof. In order to expedite the synthesis of large arrays of compounds possessing these core structures, a general methodology for solid phase synthesis of these derivatives is provided. Arrays of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antiviral, antimicrobial, anticoagulant, and antiulcer activity, or use in the treatment of inflammation, hypertension, cancer, and other conditions can be prepared by this method.

专利号:US-5861532-A
优先权日:1997-03-04
标 题:Solid-phase synthesis of N-alkyl amides
发明人：BROWN EDWARD G; NUSS JOHN M
权利人:CHIRON CORP
摘要:Methods for solid phase synthesis of N-alkyl amides comprise reductive amination of carbonyl compounds using a reducing agent and an amine-containing linker bound to a solid support. The methods afford high yields of linker-bound, monoalkylated amines, and subsequent coupling with acid derivatives provide derivatized N-substituted amides in excellent yields after cleavage from the solid-phase. Compositions useful in solid phase synthesis are also described.

专利号:US-7470370-B2
优先权日:2003-06-05
标 题 :Process for removal of impurities from mother liquor in the synthesis of carboxylic acid using pressure filtration
发明人：PARKER KENNY RANDOLPH; LIN ROBERT
权利人:EASTMAN CHEM CO
摘要:A process is disclosed that relates to the recovery of a metal catalyst from an oxidizer purge stream produced in the synthesis of carboxylic acid, typically terephthalic. More particularly, the process involves recovery of a metal catalyst from an oxidizer purge stream through the use of a pressure filter, the combining of water with a mother liquor to recover the metal catalyst and then subjecting an aqueous mixture so formed to a single stage extraction with an extraction solvent to produce an extract stream comprising organic impurities and a raffinate stream comprising the metal catalyst.

专利号:US-7494641-B2
优先权日:2003-06-05
标题 :Extraction process for removal of impurities from an oxidizer purge stream in the synthesis of carboxylic acid
发明人：LIN ROBERT; DE VREEDE MARCEL
权利人:EASTMAN CHEM CO
摘要:Disclosed is a process that relates to the recovery of a metal catalyst from an oxidizer purge stream produced in the synthesis of carboxylic acid, typically terephthalic acid. The process involves the addition of a wash solution to a high temperature molten dispersion to recover the metal catalyst and then subjecting an aqueous mixture or purified aqueous mixture so formed to a single stage extraction to remove organic impurities to produce an extract stream and a raffinate stream comprising the metal catalyst.

专利号:US-5889146-A
优先权日:1997-11-26
标题:Method for synthesis of bifunctional chelating agents-peptides
发明人：LEE TE-WEI; CHEN SHUI-TEIN; CHANG SHIANG-RONG; CHYI SHYH-YI; SHING CHANG-MAU; HUANG TIAN-FU; SHEN LIE-HANG; TSAI ZEI-TSAN; WANG KUNG-TSUNG; TING GANN
权利人:INST NUCLEAR ENERGY RES
摘要:This invention is a novel synthesis of BCA-peptides (BCA: bifunctional chelating agents). In this method, the starting material--Fmoc-Thr(ol)-Terephthal-Acetal-Amide Resin is coupled with the various amino acids. The straight peptide-resin of D-Phe-Cys(Trt)-Phe-D-Trp(Boc)-Lys(Boc)-Thr(tBu)-Cys(Trt)-Thr(ol)-Terephthal-Acetal-Amide Resin was obtained. This compound reacted with iodine to give disulfide-containing peptide resin of ##STR1## Cleavage of the peptide from the resin was achieved by TFA. The cleavaged peptide was protected by the reaction of octreotide with di-t-butyldicarbonate. BCA was coupled to the selectively protected octreotide. This product was obtained by reaction of protected BCA-peptides with TFA. The final product was labeled by radioisotope 111 InCl 3 for tumor imaging radiopharmaceuticals.

专利号:US-7452522-B2
优先权日:2003-06-05
标 题 :Extraction process for removal of impurities from an oxidizer purge stream in the synthesis of carboxylic acid
发明人：LIN ROBERT; DE VREEDE MARCEL
权利人:EASTMAN CHEM CO
摘要:Disclosed is a process that relates to the recovery of a metal catalyst from an oxidizer purge stream produced in the synthesis of carboxylic acid, typically terephthalic acid. The process involves the addition of a wash solution to a high temperature molten dispersion to recover the metal catalyst and then subjecting an aqueous mixture or purified aqueous mixture so formed to a single stage extraction to remove organic impurities to produce an extract stream and a raffinate stream comprising the metal catalyst.