CAS: 41892-01-7; N-(3-Chloro-2-Hydroxypropyl)-N,N-Dimethyldodecan-1-Aminium Chloride

该化合物是一种四化合物,具有显著的表面活性与抗微生物特性,其两栖结构具有长的缺水多丁基链和水益四丁基聚氨基混合物组,增强了溶性和表面活动,反应式的氯水化合物的存在可以进一步功能化,使其在合成和修改应用中有用.该化合物对广泛的微生物表现出强大的生物杀灭效果,使之适合消毒制剂.其水溶液稳定性和与其他表面活性剂的兼容性有助于其在工业,农业和个人护理应用中的用途.平衡的水文-脂性特性确保了各种制剂的有效乳化和分散.

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上下游产品

N,N-dimethylaminododecane 1,3-Dichloro-2-propanol dodecyldimethyl ammonium chloride epichlorohydrin

合成工艺路线路线简述

    📜十二烷基二甲基叔胺,1,3-二氯丙醇 以 乙醇 作为反应溶剂,化学反应 24.0H,以74%的收率获得产物(3-氯-2-羟基丙基)十二烷基二甲基氯化铵
    参考文献:Preparation Ofbis‐quaternary Ammonium Salts From Epichlorohydrin
    标题:Preparation Ofbis‐quaternary Ammonium Salts From Epichlorohydrin
    摘要:摘要 用 N,N-二甲基十二胺,其盐酸盐和环氧氯丙烷方便地制备了一种新型双季铵盐,且几乎定量.利用 1H 核磁共振研究了 N,N-二甲基十二胺与环氧氯丙烷(在胺盐酸盐存在下)或各种二氯化合物的反应.通过检测试剂与胺的反应性和反应温度的影响,研究了反应路线.研究发现,与环氧氯丙烷的反应之所以容易进行,是因为胺盐酸盐在打开环氧环时提供了帮助,而且中间单铵盐的羟基在季铵化步骤中参与了邻位基团.本文还讨论了羟基在这些季铵化反应中的邻基团参与.
    DOI:10.1007/bf02523450

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    专利信息


    专利号:US-10758467-B2
    优先权日:2018-05-11
    标题 :Highly substantive water-soluble UV absorbers and process for preparation thereof
    发明人：KOSHTI NIRMAL; SAWANT BHAGYESH JAGANNATH
    权利人:GALAXY SURFACTANTS LTD
    摘要:Disclosed herein are water-soluble UV absorbing compounds of Formula I with two quaternary ammonium centers, wherein; n nR is selected from saturated or unsaturated alkyl groups with C 12 to C 22 carbon atoms and R 1 is selected from H or methoxy group. The invention further discloses the synthesis of highly substantive water-soluble UV absorbers containing two quaternary ammonium centers, cinnamidopropyl (2-hydroxypropyl alkyl dimethyl ammonium chloride) dimonium chlorides of Formula I and the compositions containing the same in personal care products.

    专利号:CN-212610366-U
    优先权日:2020-06-24
    标 题 :Synthesis device of double quaternary ammonium salt intermediates

    专利号:CN-104592045-A
    优先权日:2014-12-04
    标题 :A kind of one-step synthesis method of didodecyl gamma-bisquaternary ammonium salt

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    主要参考文献

    参考标题:Highly Substantive Water-Soluble Uv Absorbers And Process For Preparation Thereof
    摘要:Disclosed Herein Are Water-Soluble Uv Absorbing Compounds Of Formula I With Two Quaternary Ammonium Centers, Wherein; R Is Selected From Saturated Or Unsaturated Alkyl Groups With C 12 To C 22 Carbon Atoms And R 1 Is Selected From H Or Methoxy Group. The Invention Further Discloses The Synthesis Of Highly Substantive Water-Soluble Uv Absorbers Containing Two Quaternary Ammonium Centers, Cinnamidopropyl (2-Hydroxypropyl Alkyl Dimethyl Ammonium Chloride) Dimonium Chlorides Of Formula I And The Compositions Containing The Same In Personal Care Products.

    合成参考文献


    摘要:Toxicology and Applied Pharmacology., 28(313), 1974 []
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