CAS: 34841-35-5; 1-(3-Chlorophenyl)Propan-1-One

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CAS号28145-63-3 3-Chlorothioben... | CAS号557-20-0 二乙基锌 | CAS号93-55-0 苯丙酮 | CAS号17408-16-1 3-硝基苯丙酮 | CAS号74-96-4 溴乙烷 | CAS号766-84-7 3-氯苯腈 | CAS号1197-05-3 1-(3-氨基苯基)丙-1-酮 | CAS号999-75-7 ethane,iodozinc(1+) | CAS号108-05-4 乙酸乙烯酯 | CAS号34911-51-8 2-溴-3'-氯苯丙酮 | CAS号350997-46-5 2-(3-氯苯基)-3-甲基喹... | CAS号34841-39-9 安非他酮 | CAS号93-54-9 1-苯基-1-丙醇 | CAS号93-55-0 苯丙酮 | CAS号92264-81-8 羟基安非他酮 | CAS号103-65-1 正丙苯溶液标准物质 | CAS号357399-43-0 羟基1-(3-氯苯基)-2-[... | CAS号18776-12-0 3-氯-1-苯基丙醇 | CAS号192374-14-4 (S,S)-羟基安非他酮

3-氯苯甲酸置于ammonium Hydroxide,氯化亚砜体系中,用 乙醇 用作溶剂,化学反应生成3'-氯丙酮苯
参考文献:Synthesis And Evaluation Of The Anticonvulsant Activity Of A Series Of 2-Amino-1-Phenyl-1-Propanols Derived From The Metabolites Of The Antidepressant Bupropion
标题:Synthesis And Evaluation Of The Anticonvulsant Activity Of A Series Of 2-Amino-1-Phenyl-1-Propanols Derived From The Metabolites Of The Antidepressant Bupropion
摘要:A Series Of 2-Amino-1-Phenyl-1-Propanols That Are Structurally Related To Known Metabolites Of Bupropion,1 (Wellbutrin(R)) Were Synthesized And Evaluated As Potential Anticonvulsants. The (R*,R*)-2-Tert-Butylamino-1-(3-Trifluoromethylphenyl) Propanol 20 Had An Ed(50) Of 16.5 +/-2.8 Mg/kg Ip In Mice In The Maximal Electroshock Screen And Was Chosen For Further Evaluation. Copyright (C) 1996 Elsevier Science Ltd
Doi:10.1016/s0960-894X(96)00577-X

专利信息

专利号:US-6838581-B2
优先权日:2002-12-04
标题:Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine
发明人：KUMAR PRADEEP; PANDEY RAJESH KUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to an improved process for the synthesis of enantiomerically pure 3-phenyl-3-hydroxypropylamine of formula I; more particularly the present invention relates to the said process using styrene; n n nthe synthetic strategy features a Sharpless asymmetric dihydroxylation (SAD) route to the target compound, using styrene, a readily accessible starting material gives the optically pure dihydroxy compound (ee >97%; the selective monotosylation of primary alcohol, nucleophilic displacement by cyano and subsequent reduction to amino group furnishes the desired 3-phenyl-3-hydroxypropylamine in enatiomerically pure form, a key intermediate in the synthesis of variety of oxetine related anti-depressant drugs.

专利号:US-11434196-B2
优先权日:2019-01-15
标 题 :Process for preparation of 2-Amino-5-hydroxy propiophenone
发明人：VASIREDDI UMA MAHESWER RAO; KINTALI VENKATA RAMANA; DADI JAGADEESWARA RAO; KATKURI RAJ KOTI; TUMMU SRIDHAR
权利人:LAURUS LABS LTD
摘要:The present invention relates to a process for preparation of 2-Amino-5-hydroxy propiophenone, a key intermediate for the synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin (SN-38).

专利号:US-6660884-B2
优先权日:2002-03-14
标 题 :Catalysts, methods for making said catalysts, and methods for making chiral compounds with high enantioselectivity
发明人：WALSH PATRICK J
权利人:UNIV PENNSYLVANIA
摘要:The present invention relates to compounds useful as catalysts in asymmetric synthesis of chiral compounds, methods for the synthesis of said catalysts, and methods for synthesizing chiral compounds with high enantioselectivity.

专利号:US-6162949-A
优先权日:1994-12-16
标 题 :Process for preparation of the pharmaceutically desired (S)-oxetine enantiomers
发明人：GATTUSO MARK J
权利人:UOP LLC
摘要:Improved processes for preparation of the (S)-oxetines in high enantiomeric purity centers on resolution using simulated moving bed chromatography of a racemic precursor early in the oxetine synthesis. Resolution is effected with high enantiomeric purity, and subsequent reactions of the desired enantiomer performed with high optical specificity to maintain enantiomeric purity. The undesired enantiomer may be racemized and recycled to the resolution phase to avoid loss.

专利号:CN-106220495-A
优先权日:2016-08-01
标题 :Method for direct synthesis of unsaturated alkene-containing alpha-acyloxyketone derivatives by α-functionalization reaction of ketones

专利号:US-5889186-A
优先权日:1994-12-16
标 题:Process for preparation of the pharmaceutically desired (S)-oxetine enantiomers
发明人：GATTUSO MARK J
权利人:UOP INC
摘要:Improved processes for preparation of the (S)-oxetines in high enantiomeric purity centers on resolution using simulated moving bed chromatography of a racemic precursor early in the oxetine synthesis. Resolution is effected with high enantiomeric purity, and subsequent reactions of the desired enantiomer performed with high optical specificity to maintain enantiomeric purity. The undesired enantiomer may be racemized and recycled to the resolution phase to avoid undesired losses.