CAS: 34202-69-2; Hexafluoroacetone Trihydrate

相似化合物

920-66-1 38701-74-5 38701-73-4

六氟丙酮 以 水 作为反应溶剂,以hexafluoroacetone Trihydrate (6Fk.3H2,0) Which Was Produced May的收率获得产物六氟丙酮水合物
参考文献:Vapor Phase Synthesis Of Hexafluoroisobutylene
标题:Vapor Phase Synthesis Of Hexafluoroisobutylene
摘要:本发明涉及六氟异丁烯的蒸汽相合成方法,包括在反应器的催化剂区b中,在蒸汽相中接触六氟丙烯氧和氟化催化剂,例如氟化硅铝土,以400oc至600oc的温度和足够的停留时间形成含有六氟丙酮的蒸汽流.然后,在反应器的加热区中,将含有产生酮的化合物,例如乙酸酐的蒸汽流直接与含有六氟丙酮的蒸汽流接触,以500oc至700oc的温度和足够的停留时间形成含有六氟异丁烯的流,该流基本上不含全氟异丁烯,并回收六氟异丁烯产品.本发明还公开了一种直接的一反应器蒸汽相合成六氟异丁烯的方法,包括(A)在氟化催化剂的存在下,在蒸汽相中,将六氟丙烯与少于将几乎所有六氟异丙烯转化为六氟丙烯氧所需的化氧物的化学计量量接触,以400oc至600oc的温度和足够的时间形成基本不含氧的六氟丙烯氧的蒸汽流;(B)在催化剂区b中直接将所述蒸汽流与含有氟化催化剂的蒸汽流接触,所述氟化催化剂最好与在催化剂区a中使用的催化剂相同,以400oc至650°C,最好是500oc至650oc的温度和足够的时间形成含有六氟丙酮的蒸汽流;(C)直接将含有六氟丙酮的蒸汽流与蒸发的化合物,例如乙酸酐,在500oc至700°C,最好是600oc的温度和足够的时间内接触,以形成基本不含全氟异丁烯的六氟异丁烯蒸汽流;和(D)回收六氟异丁烯.

专利信息

专利号:US-4705904-A
优先权日:1984-02-14
标 题:Vapor phase synthesis of hexafluoroisobutylene
发明人：BONFIELD JOHN H; ULMER HARRY E
权利人:ALLIED CORP
摘要:A vapor phase synthesis of hexafluoroisobutylene, which comprises contacting in the vapor phase in a catalyst zone, B, of a reactor hexafluoropropylene oxide with a fluorinated catalyst such as fluorinated silica-alumina at a temperature of about 400°-600° C. for a residence time sufficient to form a vapor stream comprising hexafluoroacetone which is thereafter directly contacted in a heating zone of the reactor with a vapor stream comprising a keytone-generating compound such as acetic anhydride at a temperature of about 500°-700° C. for a residence time sufficient to form a stream comprising hexafluoroisobutylene, substantially-free of perfluoroisobutylene and recovering the hexafluoroisobutylene product is disclosed. A direct one reactor vapor phase synthesis of hexafluoroisobutylene which comprises (a) contacting, in the vapor phase, hexafluoropropene with less than a stoichiometric amount of oxygen required to convert substantially all the hexafluoroisopropene into hexafluoropropylene oxide in the presence of a fluorinated catalyst such as fluorinated silica-alumina at a temperature of about 400°-600° C. for a time sufficient to form a vapor stream comprising hexafluoropropylene oxide substantially-free of oxygen; (b) directly contacting said vapor stream, in a catalyst zone, B, containing a fluorinated catalyst which is preferably the same as used in catalyst zone, A, at a temperature of about 400°-650°, preferably about 500°-650° C. for a time sufficient to form a vapor stream comprising hexafluoroacetone; (c) directly contacting the vapor stream comprising hexafluroacetone with a vaporized compound such as acetic anhydride at a temperature of about 500°-700° C., preferably about 600° C. for a time sufficient to form a vapor stream comprising hexafluoroisobutylene, substantially-free of perfluoroisobutylene; and (d) recovering hexafluoroisobutylene is also disclosed.

专利号:US-8183402-B2
优先权日:2007-06-27
标 题:Industrial method for the synthesis of 17-acetoxy-11β[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione and the key intermediates of the process
发明人：BODI JOZSEF; VISKY GYOERGY; SZELES JANOS; MAHO SANDOR; SANTA CSABA; CSOERGEI JANOS; TUBA ZOLTAN; TERDY LASZLO; MOLNAR CSABA; ARANYI ANTAL; HORVATH ZOLTAN; BALOGH GABOR
权利人:BODI JOZSEF; VISKY GYOERGY; SZELES JANOS; MAHO SANDOR; SANTA CSABA; CSOERGEI JANOS; TUBA ZOLTAN; TERDY LASZLO; MOLNAR CSABA; ARANYI ANTAL; HORVATH ZOLTAN; BALOGH GABOR; RICHTER GEDEON NYRT
摘要:The present invention relates to a process for the synthesis of the 17-acetoxy-11β-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione of formula (I): n nfrom 3,3-[1,2-etandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II):

专利号:WO-2009001148-A2
优先权日:2007-06-27
标 题:INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11β-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS

专利号:US-2010137622-A1
优先权日:2007-06-27
标 题:INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS

专利号:US-5075339-A
优先权日:1989-07-28
标 题:Benzylketone phospholipase A2 inhibitors
发明人：WILKERSON WENDELL W
权利人:DU PONT MERCK PHARMA
摘要:The invention relates to benzylketone phospholipase A2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A2-mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylketone phospholipase A2 inhibitor. These compounds are also intermediates in the synthesis of other PLA2 inhibitors.

专利号:CA-2677195-C
优先权日:2007-06-27
标 题:Industrial method for the synthesis of 17-acetoxy-11.beta.-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione and the key intermediates of the process