CAS: 91-75-8; N-Benzyl-N-((4,5-Dihydro-1H-Imidazol-2-yl)Methyl)Aniline

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CAS号36271-19-9 (苄基苯基氨基)乙腈 | CAS号107-15-3 乙二胺 | CAS号13338-49-3 2-氯甲基咪唑啉盐酸盐 | CAS号23582-63-0 Glycine, N-phen... | CAS号409111-05-3 N-benzyl-N-phen... | CAS号501-62-2 非那唑啉 | CAS号100-44-7 氯化苄

N-苄基-4,5-二氢-N-苯基-1H-咪唑-2-甲胺磷酸盐置于sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应生成 安他唑啉
参考文献:The Preparation And Characterization Of New Antazoline Salts With Dicarboxylic Acids
标题:The Preparation And Characterization Of New Antazoline Salts With Dicarboxylic Acids
摘要:New Antazoline Salts With Organic Acids (Fumaric Acid,Oxalic Acid,And Maleic Acid) Were Prepared. The Effect Of The Crystallization Solvent And Mechanochemical Treatment On The Crystalline Forms Of These Salts Was Studied. Two Polymorphs Of Antazoline Hydrogen Maleate Were Identified And Their Relative Stability Was Determined. The Molecular Structures Of Antazoline Hydrogen Oxalate And Antazoline Hydrogen Maleate Showed Differences In Antazoline Cation Conformation. In Crystal Structures Of All Salts Both Imidazoline Nitrogens Of Antazoline Cation Are Involved In Hydrogen Bond Formation With Carboxyl Groups Of The Acid.
DOI:10.1080/15421406.2014.905041

专利信息

专利号:US-11999757-B2
优先权日:2017-11-01
标 题:Synthesis of boronate ester derivatives and uses thereof
发明人：BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
权利人:MELINTA SUBSIDIARY CORP
摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

专利号:US-8734846-B2
优先权日:2008-06-16
标 题 :Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles
发明人：ALI MIR M; HRKACH JEFF; ZALE STEPHEN E; ALVAREZ DE CIENFUEGOS LUIS
权利人:BIND BIOSCIENCES INC
摘要:This application provides nanoparticles and methods of making nanoparticles using pre-functionalized poly(ethylene glycol)(also referred to as PEG) as a macroinitiator for the synthesis of diblock copolymers. Ring opening polymerization yields the desired poly(ester)-poly (ethylene glycol)-targeting agent polymer that is used to impart targeting capability to therapeutic nanoparticles. This “polymerization fromâ€? approach typically employs precursors of the targeting agent wherein the reactivity of functional groups of the targeting agent is masked using protecting groups. Also described is a “coupling toâ€? that utilized the poly(ethylene glycol)-targeting agent conjugate where the targeting agent remains in its native un-protected form. This method uses “orthogonalâ€? chemistry that exhibit no cross reactivity towards functional groups typically found within targeting agents of interest.

专利号:US-4310535-A
优先权日:1976-11-30
标题:Combination of drugs and a method for the selective control of the immune reactions evoked in a host by the administration of antigens
发明人：PIERPAOLI WALTER
权利人:PIERPAOLI WALTER
摘要:The invention concerns a new composition or combination of drugs effective to selectively control the immune reactions which are evoked in a host by the administration of antigens. It comprises active components capable of simultaneously blocking the alpha -adrenergic receptors of the cells for catecholamine, blocking the dopaminergic receptors of the cells and increasing the synthesis of serotonin. Preferred drug combinations according to the invention contain in association phentolamine, haloperidol, L-5-hydroxy-tryptophane and possibly dopamine.

专利号:US-9650407-B2
优先权日:2011-11-02
标 题 :Reprogramming of cellular adhesion
发明人：GARTNER ZEV JORDAN; SELDEN NICHOLAS SCOTT; TODHUNTER MICHAEL E; LIANG SAMANTHA ISABEL; WEBER ROBERT JOSEPH; JEE NOEL YOUNGHO; LIU JENNIFER S
权利人:UNIV CALIFORNIA
摘要:Disclosed are membrane-anchored polynucleotides, and compositions comprising the membrane-anchored polynucleotides. Also disclosed are the processes for the synthesis of these compounds, compositions comprising such compounds, and the use of such compounds and compositions in research and therapeutic applications.

专利号:US-5922335-A
优先权日:1995-05-15
标 题:Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
发明人：PTCHELINTSEV DMITRI
权利人:AVON PROD INC
摘要:Novel uses of 3'-(L-ascorbyl-2-o-phosphoryl)-cholesterol, 3'-(L-ascorbyl-3-o-phosphoryl)-cholesterol, structural or functional isomers thereof and salts thereof (referred to collectively as 'APC compounds') are disclosed. Such novel uses include a method of reducing epidermal synthesis of abnormal elastin, especially epidermal synthesis of abnormal elastin that results from exposure to UV radiation. Also disclosed is a novel method of stimulating keratinocyte formation of triglycerides. In addition, a novel method of achieving antioxidant activity, both in the skin and also in topical compositions, is disclosed.

专利号:US-2024279248-A1
优先权日:2017-11-01
标题:Synthesis of boronate ester derivatives and uses thereof