CAS: 9041-92-3; α1-Antitrypsin Human Plasma
该化合物是专门针对试剂和其他蛋白解酶(如肺癌酶)的静脉蛋白抑制剂(serpin),作为蛋白质活动的关键调节器,它在保持生理和病理过程的蛋白平衡方面发挥着关键作用.其主要功能是通过抑制试剂类静脉类静脉蛋白,保护组织免遭过度退化.Serpin A1因其抗炎,肺气肿和肝脏疾病等反炎和抗蛋白性特性的影响,受到广泛研究.其稳定的抑制机制和高度的特性使得其在生物化学,免疫学和治疗发展方面的研究具有价值.
- 英文名称α1-Antitrypsin Human Plasma
- 中文名称α1-抗胰蛋白酶(人血浆)
- 其它别名Antitrypsin, Alpha-1, Human; Anti-Trypsin, Alpha-1, Human Plasma; Alpha-1-Antitrypsin; Alpha1-Antitrypsin, Human; Alpha1-Antitrypsin, Human Plasma; Alpha-1 Antitrypsin Plasma; Alpha1-At; Alpha1-At, Human
- CAS编号9041-92-3
- MFCD编号:MFCD00130469
- EINECS号:232-924-7
- 分子式:分子量:0.0
- 产品CID: 1937074
- 产品分类原料药 → 其它化学药
物理性质
- LogP:0.0
- 溶解性Water: Soluble
- 敏感性Bi°Chem/physiol Actions 1-4 mg will inhibit 1.0 mg of trypsin with activity of 10,000 BAEE units per mg protein. 2-6 mg will inhibit approx. 1.0 mg of α-chymotrypsin with activity of 40-50 BTEE units per mg protein. Serine protease inhibitor; inhibits trypsin, chymotrypsin and pancreatic and granul°Cytic elastase, and acrosin. Effective concentration equimolar with proteinase. Caution Aqueous st°Ck solutions containing 0.01% NaN3 are stable for several months. Solutions can be stored at − 80 °C , but should not be refrozen. Unstable below pH 5.5. Inactivated by some non-serine proteinases and by oxidation of active site methionine residue. Preparation Note Chromatographically prepared and partially purified.
- 外观形态类白色不含盐的冻干粉末
- 储存条件2-8°C
- 产品应用该化合物用于生命科学研究.
