CAS: 559-74-0; Friedelin
该化合物是一种被归类为多环形三叶杆的三联苯化合物,主要来自各种植物来源,特别是在复合体家族中,其化学结构的特点是碳原子的复杂安排,其特点是一个有助于其稳定性和生物活动的引信环系系统.弗里德林通常是白到黄黄色晶状固体,熔点相对较高.它溶解于水中,但溶解于乙醇和氯仿等有机溶剂中.该化合物由于其潜在的药理特性,包括抗炎,抗氧化剂和抗微生物活动,而引起了人们的兴趣.此外,对薯条的化学和药剂研究往往以其在传统医学中的作用及其在药物开发中的潜在应用为特征.其分子配方是C30H50O,表明存在一种可促进其生物效应的氢氧化物.
- 英文名称Friedelin
- 中文名称无羁萜
- IUPAC名称(4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-octamethylicosahydropicen-3(2H)-one
- 其它别名DA-Friedooleanan-3-one(8CI); Friedelin (6CI); (-)-Friedelin; 3(2H)-Picenone, eicosahydro-4,4a,6b,8a,11,11,12b,14a-°Ctamethyl-,(4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-; 3(2H)-Picenone,eicosahydro-4,4a,6b,8a,11,11,12b,14a-°Ctamethyl-, [4R-(4a,4aa,6ab,6ba,8aa,12aa,12bb,14aa,14bb)]-; Friedelan-3-one; Friedelanone; Friedeline
- CAS编号559-74-0
- MFCD编号:MFCD00017296
- EINECS号:209-205-1
- FDA UNII编号:AK21264UAD
- 分子式:C30H50O分子量:426.73
- 产品CID: 2508394
- 产品分类天然产物 → 萜类
物理性质
MSDS等安全信息
上下游产品
CAS号6938-92-7 3-Hydroximinofr... | CAS号5085-72-3 木栓醇 | CAS号59995-80-1 21-hydroxyfried... | CAS号72154-51-9 zeylanol thiobe... | CAS号72154-54-2 zeylandiol dith... | CAS号72173-97-8 6β-Hydroxy-D:A-... | CAS号72183-93-8 kokoonol 3-ethy... | CAS号72183-92-7 kokoonol | CAS号17947-01-2 cerin acetate | CAS号127211-74-9 4-α-acetoxyfriedelin | CAS号7599-26-0 D:A-Friedoolean... | CAS号6939-65-7 FRIEDELAND, 3-M... | CAS号5309-00-2 2-[(E)-[4-(dime...合成工艺路线路线简述
- 合成目标产物 Friedelin 主要起始原料 21-Hydroxyfriedelan-3-One
- (文献来源)合成步骤主要原料 21-Hydroxyfriedelan-3-One
📜4α-Bromofriedelin置于n,N-二甲基苯胺体系中,化学反应 6.0H,反应生成 无羁萜
参考文献:Ghosh,Pranab; Chakraborty,Prasanta,Journal Of The Indian Chemical Society,2011,Vol. 88,# 7,P. 1037-1039
标题:Ghosh,Pranab; Chakraborty,Prasanta,Journal Of The Indian Chemical Society,2011,Vol. 88,# 7,P. 1037-1039
海关参考信息
- 2912110000-甲醛
2912120000-乙醛
2914110000-丙酮
2914120000-丁酮 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10751419-B2
优先权日:2014-05-01
标题:Method for synthesis of reactive conjugate clusters
发明人：MIGAWA MICHAEL T; YU JINGHUA; WAN W BRAD; PATEL SAYTEN P; VASQUEZ GUILLERMO; KINBERGER GARTH A; PRAKASH THAZHA P; SETH PUNIT P; SWAYZE ERIC E
权利人:IONIS PHARMACEUTICALS INC
摘要:Provided herein are improved methods for the synthesis of reactive conjugate clusters and intermediates used in such methods. In particular, improvements are provided that enhance the synthesis of reactive conjugate clusters by reducing the number of synthetic steps required. The reactive conjugate clusters prepared using the improved methods don't include any transacylation impurities that are formed using existing methods. The improved methods also provide an increase in overall yield and a cost benefit over existing methods.
专利号:US-12146136-B2
优先权日:2020-03-26
标题:Synthesis of modified oligonucleotides with increased stability
发明人：KHVOROVA ANASTASIA; ROUX LOÃ?C MAURICE RENÉ JEAN; YAMADA KEN
权利人:UNIV MASSACHUSETTS
摘要:This disclosure relates to the synthesis of novel modified oligonucleotides. The synthesis of novel phosphoramidites are also provided.
专利号:US-2025263763-A1
优先权日:2020-08-27
标 题 :Production of oxygenated diterpenoid compounds
发明人：ANDERSEN-RANBERG JOHAN; HANSEN NIKOLAJ; FORMAN VICTOR
权利人:UNIV COPENHAGEN
摘要:Disclosed is a method for production of oxygenated diterpenoid compounds, such as triptophenolide, triptonide and triptolide, by inserting genes encoding particular cytochrome P450 enzymes and expressing the genes in selected host cells for synthesis of the compounds. Further disclosed are particular cytochrome P450 enzymes suitable for this synthesis.
专利号:WO-2022043461-A1
优先权日:2020-08-27
标 题 :Production of oxygenated diterpenoid compounds
发明人：ANDERSEN-RANBERG JOHAN; HANSEN NIKOLAJ; FORMAN VICTOR
权利人:UNIV COPENHAGEN
摘要:Disclosed is a method for production of oxygenated diterpenoid compounds, such as triptophenolide, triptonide and triptolide, by inserting genes encoding particular cytochrome P450 enzymes and expressing the genes in selected host cells for synthesis of the compounds. Further disclosed are particular cytochrome P450 enzymes suitable for this synthesis.
专利号:US-2009131714-A1
优先权日:2005-06-08
标题:Synthesis of betulonic and betulinic aldehydes
发明人：KRASUTSKY PAVEL A; MUNSHI KALYAN
权利人:KRASUTSKY PAVEL A; MUNSHI KALYAN
摘要:The present invention provides for methods of selectively converting betulin to betulonic aldehyde. The present invention also provides for methods of selectively converting 3-substituted triterpen-28-ols to the corresponding 3-substituted triterpen-28-carboxaldehydes. Additionally, the present invention provides for methods of preparing betulonic aldehyde, betulonic acid, betulinic acid, and corresponding 3-substituted triterpenes.
专利号:US-2012184724-A1
优先权日:2009-09-22
标 题 :Protected monomers and methods of deprotection for rna synthesis
发明人：SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN
权利人:SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN; AGILENT TECHNOLOGIES INC
摘要:A nucleoside monomer that is protected by a thionocarbamate protecting group and contains one or more 2 H, 13 C, or 15 N isotopes in the ribose and/or base part is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.
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📌 第三方产品分析报告
合成参考文献
参考文献:10.1177/1087057116635503
摘要:Voter AF, Manthei KA, Keck JL. A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. J Biomol Screen. 2016 Jul;21(6):626–33.
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