CAS: 50-59-9; Cefaloridine

该化合物是属于甲状腺素类的半合成抗生素,主要用于抗菌性,对一系列抗菌素和某些抗菌菌菌有效,有助于治疗各种感染,其特点是乙状乳腺结构,这是其行动机制必不可少的,因为它抑制了细菌细胞墙合成;丙烯因口服生物利用率低,通常通过注射方式进行;其半衰期相对较短,需要多剂量才能有效治疗;已知该物质具有潜在的副作用,包括过敏反应,胃肠紊乱和...

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CAS号33465-56-4 2,2,2-trichloro... | CAS号110-86-1 吡啶 | CAS号39098-97-0 2-噻吩乙酰氯 | CAS号1918-77-0 2-噻吩乙酸 | CAS号85904-87-6 2,2,2-trichloro... | CAS号33492-94-3 2,2,2-trichloro... | CAS号85904-84-3 2,2,2-trichloro... | CAS号85904-88-7 2,2,2-trichloro... | CAS号10574-37-5 2,3-二甲基-2-戊烯 | CAS号563-45-1 异戊烯 | CAS号513-35-9 2-甲基-2-丁烯 | CAS号563-79-1 2,3-二甲基-2-丁烯 | CAS号598-23-2 3-甲基-1-丁炔 | CAS号78-79-5 异戊二烯 | CAS号75-29-6 2-氯丙烷 | CAS号107-00-6 1-丁炔 | CAS号590-19-2 1,2-丁二烯 | CAS号10482-56-1 α-松油醇

合成工艺路线路线简述

    📜2,2,2-Trichloroethyl (1S,6R,7R)-3-Chloromethyl-7-(Thien-2-Ylacetamido)Ceph-3-Em-4-Carboxylate 1-Oxide置于deacidite Ff Ion-Exchange Resin,Zinc(II) Chloride,锌,三氯化磷体系中,用 二氯甲烷,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 5.0H,反应生成 头孢噻啶
    参考文献:Synthesis Of 3-Functionalised Cephalosporins By Photoinitiated Bromination
    标题:Synthesis Of 3-Functionalised Cephalosporins By Photoinitiated Bromination
    摘要:
    DOI:10.1016/s0040-4020(01)88547-1

    海关参考信息

    专利信息


    专利号:US-6440703-B1
    优先权日:1997-12-01
    标 题 :Enzymatic synthesis of gangliosides
    发明人:DEFREES SHAWN
    权利人:NEOSE TECHNOLOGIES INC
    摘要:This invention provides methods for practical in vitro synthesis of gangliosides and other glycolipids. The synthetic methods typically involve enzymatic synthesis, or a combination of enzymatic and chemical synthesis. One or more of the enzymatic steps is preferably carried out in the presence of an organic solvent.

    专利号:US-4866175-A
    优先权日:1966-11-08
    标 题 :Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides
    发明人:ISSIDORIDES COSTAS H; HADDADIN MAKHLUF J
    权利人:RESEARCH CORP
    摘要:The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.

    专利号:US-9293230-B2
    优先权日:2013-04-17
    标题:Method for synthesis of nano-crystalline metal oxide powders
    发明人:HING PETER; MING LIM CHEE; CHEOL JUNG SANG; HUEI LOW SIAW
    权利人:Universiti Brunei Darussalam
    摘要:A method for synthesis of nanostructured metal oxide powders. The method comprises converting the metallic material into a precipitate of metal hydroxide by an electrochemical reaction and calcinating the metal hydroxide to form the metal oxides. The method of the invention is also used for the development of cermet particulates and topological insulator particles.

    专利号:EP-1685138-B1
    优先权日:2003-11-17
    标题 :Regiospecific synthesis of nicotine derivatives
    发明人:COMINS DANIEL L; KING LAURA S; DESPAGNET EMILIE
    权利人:UNIV NORTH CAROLINA STATE
    摘要:Methods of synthesizing nicotine analogs and derivatives are described. The methods are particularly useful for the regioselective production of enantiomerically pure nicotine analogs having substituents at the C4 position. Intermediates useful for the synthesis of such compounds are also described.

    专利号:EP-0034338-B1
    优先权日:1980-02-14
    标题:Catalyst for the synthesis of alcohol mixtures containing methanol and higher alcohols
    摘要:1. Catalyst for the synthesis of alcohol mixtures containing methanol and higer alcohols one the basis of starting catalysts containing copper oxide, zinc oxide and, optionally, aluminium oxide, obtainable either by (a) producing from soluble salts of copper, zinc and, optionally, aluminium (principal constituents) by joint precipitation with promoter compounds in an alkaline medium a precipitate which is calcined after removal of the impurity ions ; or by (b) impregnating a mixture of the oxides of copper, zinc, and, optionally, aluminium, with solutions of the promoter compounds and calcining the resultant product ; wherein the promoter compounds represent compounds of chromium, cerium, lanthanum, manganese, thorium or of combinations of these elements, and wherein at any desired stage of production alkali compounds are added.

    专利号:EP-1242368-B1
    优先权日:1999-12-27
    标 题 :Process for the synthesis of polycarbamates
    发明人:CHAUDHARI RAGHUNATH VITTHAL; KELKAR ASHUTOSH ANANT; GUPTE SUNIL PURUSHOTTAM; DIVEKAR SUNIL SADASHIV; GANAPATHY SUBRAMANIAN
    权利人:HUNTSMAN INT LLC
    摘要:Process for the synthesis of polyurethane derivatives from aromatic polyamine compounds. The method involves reaction of an aromatic polyamine compound with CO and O2 in the presence of a catalyst comprising a Group VIII or lanthanide metal on a solid support and a halogenide promoter.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Kano T, Kato Y, Ito K, Ogihara T, Kubo Y, Tsuji A. Carnitine/organic cation transporter OCTN2 (Slc22a5) is responsible for renal secretion of cephaloridine in mice. Drug Metab Dispos. 2009 May;37(5):1009-16. doi: 10.1124/dmd.108.025015. Epub 2009 Feb 12. doi: 10.1021/tx800008e. Epub 2008 May 23. Epub 2005 Jul 1. Epub 2005 May 7. Erratum in: Kidney Blood Press Res 1998;21(1):74.

    合成参考文献


    摘要:Chemotherapy, 26(196), 1980 []
    摘要:Byoin Yakugaku. Hospital Pharmacology., 3(220), 1978
    摘要:The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 417
    摘要:The Merck Index. 9th ed. Rahway, New Jersey: Merck & Co., Inc., 1976., p. 248
    摘要:
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