📜Icosyl Mesylate置于lithium Bromide体系中,用 四氢呋喃 作为反应溶剂,化学反应 16.0H,反应生成 溴代二十烷 参考文献:Biosynthetic Studies Of Marine Lipids. 17. The Course Of Chain Elongation And Desaturation In Long-Chain Fatty Acids Of Marine Sponges 标题:Biosynthetic Studies Of Marine Lipids. 17. The Course Of Chain Elongation And Desaturation In Long-Chain Fatty Acids Of Marine Sponges 摘要: DOI:10.1021/ja00232A025
专利号:US-10730904-B2 优先权日:2012-11-14 标 题:Method for liquid-phase synthesis of nucleic acid 发明人:NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO 权利人:TAKEDA PHARMACEUTICALS CO 摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.
专利号:US-2013190399-A1 优先权日:2009-10-31 标 题:Synthesis and use of omega-3 and omega 6 very long chain polyunsaturated fatty acids (VLC-PUFA) 发明人:RAMAN KRISHNA; TARWADE VINOD 权利人:RAMAN KRISHNA; TARWADE VINOD; MARTEK BIOSCIENCES CORP 摘要:The invention provides methods of synthesizing omega-3 and omega-6 very long chain polyunsaturated fatty acids (VLC-PUFAs, C28-C42:4, 5 and 6), analogs and derivatives thereof, pharmaceutical compositions containing these isolated VLC-PUFA compounds and therapeutic uses therefor.
专利号:US-2015315229-A1 优先权日:2012-11-14 标 题 :Method for liquid-phase synthesis of nucleic acid
专利号:CN-112047847-A 优先权日:2020-07-21 标 题 :A kind of template agent for guiding the synthesis of nano-sheet structure ZSM-5 molecular sieve and its preparation method and application
专利号:US-6512146-B2 优先权日:1998-04-28 标 题 :Process for preparing a dialkyl acetal of a C8 to C30 aldehyde 发明人:PAULEY EDWARD P; NEIGHBOR KATHERINE SUE 权利人:PENFORD CORP 摘要:Improved water resistant acetal sizing agents including 1,1-octadecoxyoctadecane are provided along with methods for their synthesis including methods in which C 8 to C 30 alkyl bromides are reacted with a polyol under basic conditions and those in which a C 8 to C 30 primary alcohol is reacted with an organic base in the presence of a suitable oxidizing agent under basic conditions.
专利号:US-10214555-B2 优先权日:2012-11-14 标题 :Method for liquid-phase synthesis of nucleic acid