CAS: 393-52-2; 2-Fluorobenzoyl Chloride

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CAS号445-29-4 邻氟苯甲酸 | CAS号3416-93-1 2-(4,5-dihydro-... | CAS号110623-32-0 5-(2-fluorophen... | CAS号342-25-6 2,4'-二氟二苯甲酮 | CAS号363-34-8 (2-氟苯甲酰基氨基)-乙酸 | CAS号92-52-4 联苯 | CAS号342-24-5 2-氟二苯甲酮 | CAS号3722-51-8 3-羟基-9H-占吨-9-酮 | CAS号31915-26-1 2-氟苯甲酰乙腈 | CAS号443-26-5 邻氟苯甲酸乙酯 | CAS号348-54-9 邻氟苯胺 | CAS号394-35-4 邻氟苯甲酸甲酯

邻氟苯甲酸置于氯化亚砜体系中,化学反应 2.0H,反应生成 邻氟苯甲酰氯
参考文献:通过分子内氢键分析远程空间耦合
标题:通过分子内氢键分析远程空间耦合
摘要:2-氟苯甲酰胺及其 N-甲基衍生物显示出芳族氟与酰胺基团的氮和碳之间的自旋-自旋偶联,而相应的 N,N-二甲基酰胺中不存在这种偶联.n-甲基化合物,其中氟和酰胺氢之间有一个氢键,也显示出与甲基核的氟偶联,而这些在酰胺在极性溶剂中的溶液中会减弱.n,N-二甲基酰胺中不存在这种偶联,然而,N,N-二甲基酰胺确实显示出与邻近甲基的氟偶联.使用 Ippp 方法在 Indo 水平上的计算与观测到的 4J(F,
DOI:10.1002/mrc.1260310909

专利信息

专利号:US-5077408-A
优先权日:1989-09-20
标 题 :Process for the synthesis of oxazolopyridine compounds
发明人：GUILLAUMET GERALD; FLOUZAT CHRISTINE
权利人:SCIENCE ORGANISATION
摘要:Process for the synthesis of compounds of formula (I): ##STR1## their pyridinium salts and N-oxides, in which formula: the nitrogen of the pyridine ring is situated in the α-, β-, γ- or δ-position with respect to the ring junction; n R 1 represents a halogen, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkoxy or a nitro, substituted or unsubstituted amino, phenyl or cyano group; n 0≦m≦2; n R 2 represents a lower alkyl or cycloalkyl group, a 5- or 6-membered heterocycle containing 1 or 2 hetero atoms, substituted or otherwise, or an aryl group ##STR2## such that: R 3 represents a halogen, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkoxy or a nitro, phenyl, substituted or unsubstituted sulfonyl, cyano, thioalkyl, substituted or unsubstituted amino, substituted or unsubstituted sulfinyl, mercapto, hydroxyl or ester group, n 0≦n≦5 n employing trimethylsilyl polyphosphate (PPSE) as a cyclization agent and enabling the compounds of formula (I) to be obtained in virtually quantitative yields. The compounds of formula I have anti-inflammatory, analgesic, and antipyretic activity.

专利号:US-9409879-B2
优先权日:2011-03-29
标 题 :Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
发明人：DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA
权利人:DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA; CENTRE NAT RECH SCIENT
摘要:Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents.

专利号:US-11008273-B2
优先权日:2019-02-15
标题 :Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof
发明人：ZHOU CHANGYUE; DU HONGJUN; WU WENTING
权利人:FUJIAN YONGJING TECH CO LTD
摘要:The invention relates to a new process for the manufacture or synthesis, respectively, of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof, in particular of fluorobenzenes and derivatives thereof. The present invention particularly pertains to a novel environmentally friendly process for the synthesis of fluorinated benzenes and benzophenones as raw materials for the manufacture of polyaryletherketones (PAEKs).

专利号:US-11981648-B2
优先权日:2019-06-13
标题:Method for the synthesis of 3-R-1,4,2-dioxazol-5-ones
发明人：HALL DAVID S; DAHN JEFFERY RAYMOND; HYNES TOREN
权利人:TESLA INC; PANASONIC HOLDINGS CORP
摘要:Provided are methods of preparing 3-R-1,4,2-dioxazol-5-one compounds using convenient and efficient methods. Also provided are 3-R-1,4,2-dioxazol-5-one compounds produced using the methods described.

专利号:WO-2011106986-A1
优先权日:2010-03-02
标题:Inhibitors of hepatitis c virus ns5b polymerase
发明人：MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO
权利人:MERCK SHARP & DOHME; MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO
摘要:Compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and /or viral production in a cell-based system. Wherein Z, R 30 , R 40 , R 50 and R 60 of compounds of formula (I) are herein defined as in the description.

专利号:US-3862209-A
优先权日:1972-05-12
标题:Process of making nitro phenoxybenzoic acid esters
发明人：THEISSEN ROBERT JAMES
权利人:MOBIL OIL CORP
摘要:Improved process for the synthesis of certain nitro phenoxybenzoic acid esters in which high yield, high purity, herbicidally effective compounds are obtained. In general the improvement comprises: 1. ESTERIFICATION OF A HALOBENZOYL HALIDE WITH ISOPROPANOL THEREBY FACILITATING SEPARATION OF ISOMERIC IMPURITIES FROM THE DESIRED ISOPROPYL-NITROBENZOATE ESTER INTERMEDIATE. 2. TRANSESTERIFICATION OF A PHENOXY DERIVATIVE OF SAID ESTER TO THE DESIRED PHENOXYBENZOIC ACID ESTER.