专利号:US-2011152313-A1 优先权日:2008-06-20 标题 :Synthesis of ageladine a and analogs thereof 发明人:KARUSO PETER HELMUTH; SHENGULE SUDHIR RAMNATHRAO 权利人:UNIV MACQUARIE 摘要:The invention describes a one pot process for synthesizing a compound of structure (I), or a tautomer thereof. A compound of structure (II), or a tautomer thereof, and an aldehyde of structure R d CHO are condensed to form a condensation product. The resulting condensation product is then oxidized in the same reaction mixture to produce the compound of structure (I) or a tautomer thereof.
专利号:US-8962839-B2 优先权日:2010-11-19 标题:Chiral spiro-pyridylamidophosphine ligand compound, synthesis method therefor and application thereof 发明人:ZHOU QILIN; XIE JIANHUA; LIU XIAOYAN; XIE JIANBO; WANG LIXIN 权利人:ZHOU QILIN; XIE JIANHUA; LIU XIAOYAN; XIE JIANBO; WANG LIXIN; ZHEJIANG JIUZHOU PHARMA SCIENCE & TECHNOLOGY CO LTD 摘要:The present invention relates to a chiral spiro-pyridylamidophosphine ligand compound, synthesis method therefor and application thereof. The chiral spiro-pyridylamidophosphine compound is a compound having a structure of Formula (I), a racemate or optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly characterized by having a chiral spiro-dihydro-indene skeleton in its structure. The chiral spiro-pyridylamidophosphine compound may be synthesized with optical active 7-diaryl/alkylphosphino-7′-amino-1,1′-spiro-dihydro-indene or substituted 7-diaryl/alkylphosphino-7′-amino-1,1′-spiro-dihydro-indene having a spiro-skeleton as chiral starting material. The chiral spiro-pyridylamidophosphine compound may be used as a chiral ligand in asymmetric hydrogenation of a carbonyl compound catalyzed by iridium, in which the reaction activity is very high, the amount of the catalyst may be 0.0001 mol %, and the enantioselectivity of the reaction is up to 99.9% ee.
专利号:CN-115318342-A 优先权日:2022-09-13 标 题 :Heterogeneous bimetallic platinum catalyst and application thereof in synthesis of gamma-chloropropyltrichlorosilane
专利号:CN-115382580-A 优先权日:2022-09-13 标题:Heterogeneous platinum catalyst and application thereof in synthesis of gamma-chloropropyltrichlorosilane
专利号:CN-115382580-B 优先权日:2022-09-13 标 题:Heterogeneous platinum catalyst and application thereof in synthesis of gamma-chloropropyl trichlorosilane
专利号:WO-2009152584-A1 优先权日:2008-06-20 标题 :Synthesis of ageladine a and analogs thereof
[参考文献]: Awatef Ayadi, Et Al. Tetrathiafulvalene-Based Azine Ligands For Anion And Metal Cation Coordination. Beilstein J Org Chem. 2015 Aug 7:11:1379-91. [参考文献]: Francesca A Scaramuzzo, Et Al. Determination Of Amino Acid Enantiopurity And Absolute Configuration: Synergism Between Configurationally Labile Metal-Based Receptors And Dynamic Covalent Interactions. Chemistry. 2013 Dec 2;19(49):16809-13. [参考文献]: Magdalena M Makowska-Grzyska, Et Al. First Row Divalent Transition Metal Complexes Of Aryl-Appended Tris((Pyridyl)Methyl)Amine Ligands: Syntheses, Structures, Electrochemistry, And Hydroxamate Binding Properties. Inorg Chem. 2003 Nov 17;42(23):7472-88.
合成参考文献
摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 245. 摘要:Murai, K.; Fujioka, H., Science of Synthesis Knowledge Updates, (2016) 2, 295. 摘要:Schleicher, K. D.; Jamison, T. F., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 548. 摘要:Lin, Z.; Tao, R.; Zhao, Y., Science of Synthesis: Knowledge Updates, (2023) 1, 393.