CAS: 298-81-7; 9-Methoxy-7H-Furo[3,2-G]Chromen-7-One

相似化合物

2009-24-7 484-20-8 133643-33-1

上下游产品

CAS号2009-24-7 花椒毒酚,花椒毒醇 | CAS号77-78-1 硫酸二甲酯 | CAS号66510-32-5 2-hydroxy-9-met... | CAS号66510-36-9 7-Acetoxy-6-(fo... | CAS号10386-19-3 7H-Furo[3,2-g][... | CAS号74-88-4 碘甲烷 | CAS号186581-53-3 重氮甲烷 | CAS号69151-97-9 9-Methoxy-7-oxo... | CAS号14348-23-3 4,9-dihydroxyfu... | CAS号482-27-9 异茴芹灵 | CAS号1930-56-9 7H-Furo[3,4-g][... | CAS号1930-54-7 7H-Furo[3,2-g][... | CAS号2009-24-7 花椒毒酚,花椒毒醇 | CAS号102826-90-4 3-(6-hydroxy-7-... | CAS号610-02-6 2,3,4-三羟基苯甲酸 水合物 | CAS号68123-30-8 甲氧沙林中间体 | CAS号15558-40-4 9-butoxyfuro[3,... | CAS号100953-16-0 5,6-二氢-9-甲氧基-7H...

2-Hydroxy-9-Methoxy-2,3-Dihydro-7H-Furo[3,2-G][1]Benzopyran-7-One置于氩,Alumina体系中,用 甲酸 用作溶剂,化学反应 0.75H,以afforded Pure Methoxsalen,Mp 145°-146°的收率获得8-甲氧基补骨脂素
参考文献:8-Methoxypsoralen Derivatives
标题:8-Methoxypsoralen Derivatives
摘要:本发明涉及合成过程,用于生产已知的药理活性8-甲氧基紫檀酮及其衍生物.同时还披露了用于这些过程的各种新型中间体.

专利信息

专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人：ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.

专利号:US-2012177593-A1
优先权日:2009-07-20
标 题 :Synthesis of dendrimer conjugates
发明人：BAKER JR JAMES R; ZHANG YUEHUA; THOMAS THOMMEY P; DESAI ANKUR MAHESH
权利人:BAKER JR JAMES R; ZHANG YUEHUA; THOMAS THOMMEY P; DESAI ANKUR MAHESH; UNIV MICHIGAN
摘要:The present invention relates to novel methods of synthesis of therapeutic and diagnostic dendrimers. In particular, the present invention is directed to novel dendrimer conjugates, novel methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer, inflammatory disease) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer conjugates of the present invention may further comprise at least two different components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy. Furthermore, the novel synthesis methods of certain embodiments of the present invention provide significant advantages with regard to total reaction time and simplicity.

专利号:US-6660305-B1
优先权日:1998-07-28
标题 :Composition for stimulating the synthesis of the melanic pigment and process for obtaining it
发明人：CAO CARLOS M MIYARES
权利人:CT DE HISTOTERAPIA PLACENTARIA
摘要:This invention relates to the field of human medicine, more specifically to dermatology, and in particular to a composition developed for the stimulation of the synthesis of the melanic pigment of the skin, therefore useful for the treatment of vitiligo. The technical goal of this invention is to provide a composition of natural origin useful in the treatment of vitiligo that has no toxic effects and no relapse. The composition obtained stimulates the synthesis of the melanic pigment of the skin and the reproduction of melanocytes, as demonstrated through pharmacological tests to which the composition was subjected, causing no serious secondary reactions at all, as demonstrated in the toxicological, teratological and clinical tests performed. The resulting product can easily be obtained and applied, repigmentation begins rapidly after initiating the treatment, and the effect is irreversible. The color acquired is identical to the color of the normal skin areas of the patient, but these areas do not further increase the intensity of their coloration after the product has been applied. The product can also be used for the treatment of any depigmentation process of the skin, for example, that caused by burns.

专利号:US-9440940-B2
优先权日:2014-03-18
标 题:Methods for synthesis of psoralen derivatives
发明人：REFOUVELET BERNARD
权利人:MACOPHARMA S A S
摘要:Methods for the synthesis of psoralen derivatives are provided. In one embodiment, the method may include acetylating a compound of formula (II) to form a compound of formula (III), subjecting the compound of formula (III) to a Fries rearrangement to form a compound of formula (IV), and subjecting the compound of formula (IV) to cyclization, reduction and aromatization, to form a compound having the following formula (I):

专利号:WO-9611194-A1
优先权日:1994-10-06
标题:Pyridonecarboxylic acid derivative and intermediate for the synthesis of the same
发明人：OKADA HIDETSUGU; CHIBA KATSUMI; TOMINAGA YUKIO; MINAMI AKIRA
权利人:DAINIPPON PHARMACEUTICAL CO; OKADA HIDETSUGU; CHIBA KATSUMI; TOMINAGA YUKIO; MINAMI AKIRA
摘要:A pyridonecarboxylic acid derivative represented by general formula (I), an ester and a salt thereof, an antibacterial agent containing the same, and a bicyclic amine compound serving as a direct intermediate for the synthesis of the pyridonecarboxylic acid derivative, wherein R represents cycloalkyl, optionally substituted phenyl, etc.; G represents carbon, etc.; A represents C-Z (Z being hydrogen, halogeno, lower alkoxy, etc.) or nitrogen; X represents hydrogen, amino, etc.; Y represents hydrogen or halogeno; m is an integer of 1 to 3; and W represents -(CH2)nN(R1)R2 (R1 and R2 being the same or different and each representing hydrogen, lower alkyl, etc., and n being an integer of 0 or 1).

专利号:US-9254327-B2
优先权日:2010-05-10
标 题 :Methods and compositions for delivery of active agents
发明人：MANOHARAN MUTHIAH; RAJEEV KALLANTHOTTATHIL G
权利人:MANOHARAN MUTHIAH; RAJEEV KALLANTHOTTATHIL G; ALNYLAM PHARMACEUTICALS INC
摘要:A lipid particle can include a cationic lipid. Synthesis of the cationic lipid can include a ylide-based reaction, such as a Wittig reaction or sulfur ylide reaction. In some cases, the synthesis can also include a Michael addition or a related addition reaction.