CAS: 1813-96-3; 3-[(3-Trifluoromethyl)Phenyl]-1-Propene
该化合物是一种有机化合物,其特点是芳香结构,包括一个苯环,由一个环状体组和一个三氟甲基组替代,三氟硫基组(CF3)的存在对化合物的化学特性产生重大影响,导致高电子密度和脂性,从而可以增强该化合物在各种化学反应中的回作用.Allyl(-CH2-CH=CH2)组引入了一个潜在聚合或进一步功能化的场所.该化合物一般色素不高,表面看起来不浅,可能具有独特的气味.它一般在水中不溶,但有机溶剂中可溶解,因此在各种应用中有用,包括作为有机合成的中间体以及生产药品和农用化学品.安全数据应当用于处理,因为有三氟基化合物的化合物可以表现出毒性和环境持久性.
- 英文名称3-[(3-Trifluoromethyl)Phenyl]-1-Propene
- 中文名称1-(2-丙烯-1-基)-3-(三氟甲基)苯
- IUPAC名称1-allyl-3-(trifluoromethyl)benzene
- 其它别名4-Allyl(Trifluoromethyl)Benzene; 1-Allyl-3-(Trifluoromethyl)Benzene; Benzene, 1-(2-Propen-1-yl)-3-(Trifluoromethyl)-; 1-(2-Propen-1-yl)-3-(Trifluoromethyl)Benzene
- CAS编号1813-96-3
- MFCD编号:MFCD09801107
- 分子式:C10H9F3分子量:186.18
- 产品CID: 934740
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
MSDS等安全信息
上下游产品
CAS号401-78-5 间溴三氟甲苯 | CAS号591-87-7 乙酸烯丙酯 | CAS号54509-73-8 ethene | CAS号705-29-3 3-三氟甲基氯苄 | CAS号107-05-1 氯丙烯 | CAS号75-04-7 乙胺 | CAS号402-26-6 间(三氟甲基)苯基溴化镁 | CAS号106-95-6 烯丙基溴 | CAS号458-24-2 左芬氟拉明 | CAS号402-24-4 3-(三氟甲基)苯乙烯合成工艺路线路线简述
- 合成目标产物 3-[(3-Trifluoromethyl)Phenyl]-1-Propene 主要起始原料 3-Bromobenzotrifluoride And Allyl Chloride
- (文献来源)合成步骤主要原料 3-Bromobenzotrifluoride 和 Allyl Chloride
📜间溴三氟甲苯,乙酸烯丙酯置于magnesium,Lithium Chloride,Iron(III)-Acetylacetonate体系中,用 四氢呋喃 用作溶剂,化学反应 2.83H,反应生成1-烯丙基-3-(三氟甲基)苯
参考文献:末端环氧化物的区域和化学选择性重排成甲基烷基和芳基酮†
标题:末端环氧化物的区域和化学选择性重排成甲基烷基和芳基酮†
摘要:提出了在温和条件下将官能化的末端环氧化物亲核性迈恩瓦尔德重排成甲基酮的高活性钳型铑催化剂2的开发.芳基环氧乙烷首次获得了优异的区域选择性和化学选择性.
Doi:10.1039/c8Cc06503A
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2903399090-其他无环烃卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10266503-B1
优先权日:2016-05-24
标 题 :Sulfoxide ligand metal catalyzed oxidation of olefins
发明人：WHITE M CHRISTINA; AMMANN STEPHEN E; LIU WEI; MA RULIN
权利人:UNIV ILLINOIS
摘要:The enantioselective synthesis of isochroman motifs has been accomplished via Pd(II)-catalyzed allylic C—H oxidation from terminal olefin precursors. Critical to the success of this goal was the development and utilization of a novel chiral aryl sulfoxide-oxazoline (ArSOX) ligand. The allylic C—H oxidation reaction proceeds with the broadest scope and highest levels asymmetric induction reported to date (avg. 92% ee, 13 examples ≥90% ee). Additionally, C(sp 3 )-N fragment coupling reaction between abundant terminal olefins and N-triflyl protected aliphatic and aromatic amines via Pd(II)/sulfoxide (SOX) catalyzed intermolecular allylic C—H amination is disclosed. A range of 52 allylic amines are furnished in good yields (avg. 76%) and excellent regio- and stereoselectivity (avg. >20:1 linear:branched, >20:1 E:Z). For the first time, a variety of singly activated aromatic and aliphatic nitrogen nucleophiles, including ones with stereochemical elements, can be used in fragment coupling stiochiometries for intermolecular C—H amination reactions.
专利号:US-2018208543-A1
优先权日:2017-01-26
标 题 :New method for synthesis of fenfluramine, and new compositions comprising it
发明人：PALOMBI GIOVANNI; ZAGAMI MICHAEL
权利人:FRAU PHARMA S R L
摘要:A new process for preparing the fenfluramine molecule and new compositions containing fenfluramine obtainable with the claimed process.
专利号:EP-3170807-A1
优先权日:2015-11-23
标题:New method for synthesis of fenfluramine, of isomers therof and/or of analogs thereof, and new compositions comprising it
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Sulfoxide Ligand Metal Catalyzed Oxidation Of Olefins摘要:The Enantioselective Synthesis Of Isochroman Motifs Has Been Accomplished Via Pd(II)-Catalyzed Allylic C-H Oxidation From Terminal Olefin Precursors. Critical To The Success Of This Goal Was The Development And Utilization Of A Novel Chiral Aryl Sulfoxide-Oxazoline (Arsox) Ligand. The Allylic C-H Oxidation Reaction Proceeds With The Broadest Scope And Highest Levels Asymmetric Induction Reported To Date (Avg. 92% Ee, 13 Examples >=90% Ee). Additionally, C(Sp3)-N Fragment Coupling Reaction Between Abundant Terminal Olefins And N-Triflyl Protected Aliphatic And Aromatic Amines Via Pd(II)/sulfoxide (Sox) Catalyzed Intermolecular Allylic C-H Amination Is Disclosed. A Range Of 52 Allylic Amines Are Furnished In Good Yields (Avg. 76%) And Excellent Regio- And Stereoselectivity (Avg. >20:1 Linear:Branched, >20:1 E:Z). For The First Time, A Variety Of Singly Activated Aromatic And Aliphatic Nitrogen Nucleophiles, Including Ones With Stereochemical Elements, Can Be Used In Fragment Coupling Stiochiometries For Intermolecular C-H Amination Reactions.
合成参考文献
参考文献:10.1055/s-0040-1706085
摘要:Gale-Day ZJ. Recent Advances in Metal-Catalyzed, Electrochemical Coupling Reactions of sp2 Halides/Boronic Acids and sp3 Centers. Synthesis. 2020 Nov 24;53(05):879–88. doi: 10.1055/s-0040-1706085.
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