CAS: 10401-55-5; Hexadecyl (Z,12R)-12-Hydroxyoctadec-9-Enoate

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    专利号:US-10799441-B2
    优先权日:2011-06-06
    标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
    发明人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
    权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
    摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

    专利号:US-10973748-B2
    优先权日:2016-04-21
    标题:Compositions and methods for lightening skin and reducing hyperpigmentation
    发明人:WANG MINGFU; HU SHU TING; Wu yi zhen
    权利人:VERSITECH LTD
    摘要:The composition includes a cyclic, unsaturated compound, preferably a polyphenol derivative. It reduces the synthesis of melanin by inhibiting the activity and expression levels of tyrosinase and related proteins, thereby preventing and limiting the content and distribution of melanin in mammalian skin. It also induces autophagy of melanosome, thereby restricting the synthesis, storage and transfer of melanin from melanocyte to keratinocyte. The dual modes of action allow for the efficacy of the composition at low dosage without causing toxicity to lighten skin and treat disorders associated with hyperpigmentation.

    专利号:US-6150403-A
    优先权日:1997-10-14
    标 题 :Topical compositions for regulating the oily/shiny appearance of skin
    发明人:BIEDERMANN KIMBERLY A; SCHUBERT HARRY L; PARRAN JR JOHN J
    权利人:PROCTER & GAMBLE
    摘要:The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.

    专利号:WO-2020165135-A1
    优先权日:2019-02-11
    标 题:Acrylic copolymer capsule designed to open up at < 90°c for controlled release of in-situ forming pu/pir catalyst
    发明人:LIESE JULIA; ZHANG LI; STAFF ROLAND HINRICH; BEZIAU ANTOINE MAXIME CHARLES JOSEPH
    权利人:BASF SE
    摘要:The present invention relates to a catalyst useful for polyurethane or polyisocyanurate synthesis comprising an aqueous and/or alcoholic solution of lithium chloride encapsulated in a (meth)acrylic copolymer capsule shell, wherein the (meth)acrylic copolymer capsule shell is obtained or obtainable by reacting: i) 10 to 90 weight-% of a first (meth)acrylate composition comprising a polyester of (meth)acrylic acid with a C2 to C24 alkylpolyol; ii) 90 to 10 weight-% of a second (meth)acrylate composition comprising a monoester of (meth)acrylic acid with a C1 to C24 alkanol; wherein the weight-% are based on an overall weight of all (meth)acrylates of 100 weight-%. In further aspects, the invention relates to a catalytic composition comprising the catalyst and an epoxide composition; a process for preparation of an aqueous and/or alcoholic solution of lithium chloride encapsulated in a (meth)acrylic copolymer capsule shell, and also to an aqueous and/or alcoholic solution of lithium chloride encapsulated in an acrylic copolymer capsule shell obtained or obtainable from the process, as well as to the use of the catalyst or of the aqueous and/or alcoholic solution of lithium chloride encapsulated in an acrylic copolymer capsule shell obtained or obtainable from the process for the preparation of polyurethane or polyisocyanurate. The invention also relates to a polyurethane or polyisocyanurate obtained or obtainable from the reaction of at least: a) a polyisocyanate composition; b) a polyol composition; in the presence of an epoxide composition and a catalyst comprising an aqueous and/or alcoholic solution of lithium chloride encapsulated in a (meth)acrylic copolymer capsule shell, wherein the (meth)acrylic copolymer capsule shell is obtained or obtainable by reacting: i) 10 to 90 weight-% of a first (meth)acrylate composition comprising a polyester of (meth)acrylic acid with a C2 to C24 alkylpolyol; ii) 90 to 10 weight-% of a second (meth)acrylate composition comprising a monoester of (meth)acrylic acid with a C1 to C24 alkanol; wherein the weight-% are based on an overall weight of all (meth)acrylates of 100 weight-%. Furthermore, the invention relates to a process for the preparation of the polyurethane or polyisocyanurate.

    专利号:WO-2011061144-A2
    优先权日:2009-11-20
    标题:The present invention relates to the use of beta-(1, 3)- beta-(1, 4) glucan with an average molecular weight of from 5.000 to 150.000 da for the increase of synthesis of collagen

    专利号:US-7825161-B2
    优先权日:2003-12-15
    标题 :Higher fullerenes useful as radical scavengers
    发明人:KRONHOLM DAVID F; HUMMELEN JAN C; SIEVAL ALEXANDER B
    权利人:NANO C INC
    摘要:Chemically functionalized fullerenes are useful in various applications as radical scavengers. These chemically functionalized fullerenes offer the advantages of preservation of the high innate radical scavenging efficiency of the fullerene cage and ease of synthesis of fullerene derivatives of desirably altered chemical and physical properties and single isomers. Further, they are based on a common intermediate chemistry and intermediates can be easily functionalized and tailored to various requirements.

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    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 26(Suppl. 3):31-77, 2007
    摘要:International Journal of Toxicology 34(Suppl.2):5-69, 2015
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