CAS: 90381-07-0; 5-Chloro-2-(Trifluoromethyl)Benzaldehyde

该化合物是一种芳香藻,其特点是存在一个氯组和一个附于苯环的三氟甲基组,该化合物的特点是苯甲醚功能组,以其在各种有机合成反应中,特别是核生殖添加和凝聚反应中的活性而闻名.三氟甲基组的存在对其电子特性有重大影响,增强了其脂性,并有可能由于氟原子的强烈电回悬性质而增加其回活动.氯代成分还有助于该化合物的整体回活动,并可参与进一步的化学变异.一般而言,该化合物用于合成药物,农用化学品和其他精密化学品,其物理特性,例如沸点和溶性,受到苯环亚组的物理特性的影响,使其在合成化学和药用化学环境中都是一种有趣的复变复合.在处理该化合物时,由于其潜在的毒性和再活性,应当注意安全防范.

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CAS号261763-21-7 5-氯-2(三氟甲基)苯甲醇 | CAS号7664-93-9 硫酸 | CAS号320-84-3 5-Chloro-2-(tri...

合成工艺路线路线简述

  • 合成目标产物 5-Chloro-2-(Trifluoromethyl)Benzaldehyde 主要起始原料 5-Chloro-2-(Trifluoromethyl)Benzyl Alcohol
  • (文献来源)合成步骤主要原料 5-Chloro-2-(Trifluoromethyl)Benzyl Alcohol
📜4-Chloro-2-Difluoromethyl-1-Trifluoromethyl-Benzene 反应生成 5-氯-2-三氟甲基苯甲醛
参考文献:Trifluoromethyl Benzaldehydes
标题:Trifluoromethyl Benzaldehydes

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专利信息


专利号:US-9446047-B2
优先权日:2013-09-10
标 题 :Substituted 2,3-dihydro-1H-inden-1-one retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
发明人:VANKAYALAPATI HARIPRASAD; YERRAMREDDY VENKATAKRISHNAREDDY
权利人:ARRIEN PHARMACEUTICALS LLC
摘要:The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related orphan nuclear receptor γt (RORγt)/RORγ. The compounds of the present invention are useful for modulating RORγt)/RORγ activity and for treating diseases or conditions mediated by RORγt)/RORγ such as for example, disease states associated with immunopathology of human autoimmune diseases such as Multiple Sclerosis (MS), Rheumatoid Arthritis (RA), Inflammatory Colitis, Psoriasis, COPD, Pain, Obesity, Diabetes, Dyslipidemia, Osteoporosis, Asthma, Neurodegenerative diseases and Cancer.

专利号:EA-020243-B1
优先权日:2009-05-29
标题:SPYROEPOXIDES AS INTERMEDIATE PRODUCTS OF SYNTHESIS

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