专利号:US-5939304-A 优先权日:1997-06-05 标题:Method for synthesis of anhydrothrombin 发明人:SUZUKI TOYOAKI; HOSOKAWA KAZUYA; NAGATA MASANORI 权利人:FUJIMORI KOGYO CO 摘要:A method for a synthesis of anhydrothrombin is provided which features a short process, an easy procedure, and high yields. n The method comprises n (A) a step of causing an active serine residue site of thrombin to react with an inhibitor, n (B) a step of performing an alkali treatment at a pH of not less than 11, and n (C) a step of performing an operation of recovery, and carries out these steps sequentially in the order mentioned, and is characterized by causing at least the step of performing the operation of recovery to proceed in the presence of at least one compound selected from the group consisting of polyhydric alcohols and saccharides, and a salt or an amphoteric electrolyte.
专利号:US-8105809-B2 优先权日:2008-07-03 标题 :Enzymatic synthesis of acetoacetate esters and derivatives 发明人:HENDERSON SAMUEL T 权利人:HENDERSON SAMUEL T; ACCERA INC 摘要:In one embodiment, the present invention includes a method for the synthesis of an ester derivative of acetoacetate. The method includes providing a first ester of acetoacetate and providing an alcohol. The method further includes combining the first ester of acetoacetate and the alcohol in the presence of an enzyme capable of transesterification in a non-aqueous solvent to form the ester derivative of acetoacetate. The method results in the formation of the ester derivative of acetoacetate, which, in one embodiment, is monoacetoacetin.
专利号:US-2006030625-A1 优先权日:2004-08-06 标 题 :Dietary neurotransmitter precursors for balanced synthesis of neurotransmitters 发明人:HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT 权利人:HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT 摘要:Dietary supplements for treating a neurotransmitter deficiency include one or more precursors of the deficient neurotransmitter and a cofactor for activating in vivo enzymatic synthesis of the deficient neurotransmitter. The dietary supplements can also include an appropriate neurotransmitter, such as an amino acid. When administered through the oral mucosa, increases in levels of the deficient neurotransmitters and relief from deficiency symptoms are obtained.
专利号:US-2017204442-A1 优先权日:2014-05-29 标题 :Enzymatic synthesis of soluble glucan fiber 发明人:DICOSIMO ROBERT; CHENG QIONG; ELIOT ANDREW C; OUWEHAND ARTHUR; PAYNE MARK S; YOU ZHENG 权利人:DU PONT 摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
专利号:US-10442830-B2 优先权日:2014-12-03 标题:Synthesis of monoethers of sugar comprising a long alkyl chain and uses thereof as a surfactant 发明人:GOZLAN CHARLOTTE; DUCLOS MARIE-CHRISTINE; DUGUET NICOLAS; LEMAIRE MARC; REDL ANDREAS 权利人:TEREOS STARCH & SWEETENERS BELGIUM; UNIV CLAUDE BERNARD LYON; CENTRE NAT RECH SCIENT 摘要:A process for obtaining a mixture of C4-C8 and C9-C18 alkyl monoether of saccharide, comprising: a) a first step of acetalization or trans-acetalization of a saccharide or of a mixture of saccharides with a C4-C8 aliphatic aldehyde or the acetal thereof, b) a second consecutive or simultaneous step of acetalization or trans-acetalization of the product obtained in a) of the saccharide or mixture of saccharides with a C9-C18 aliphatic aldehyde or the acetal thereof, c) a step of catalytic hydrogenolysis of the saccharide acetals obtained, and d) a step of recovery of a mixture of C4-C8 and C9-C18 alkyl saccharide monoethers. The invention further relates to a mixture of C4-C8 and C9-C18 alkyl saccharide monoethers and the use thereof as a surfactant.
专利号:US-10907185-B2 优先权日:2014-05-29 标 题 :Enzymatic synthesis of soluble glucan fiber 发明人:CHENG QIONG; DICOSIMO ROBERT; OUWEHAND ARTHUR; YOU ZHENG; LAI JIAN PING; YU ZHEYONG; ZHANG ZHENGHONG 权利人:DUPONT IND BIOSCIENCES USA LLC 摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
1: Saraiva A, Carrascosa C, Raheem D, Ramos F, Raposo A. Maltitol: Analytical Determination Methods, Applications in the Food Industry, Metabolism and Health Impacts. Int J Environ Res Public Health. 2020 Jul 20;17(14):5227. doi: 10.3390/ijerph17145227. 2: Rasouli Pirouzian H. Using maltitol and xylitol as alternative bulking agents in milk chocolate: modelling approach. J Food Sci Technol. 2022 Jun;59(6):2492-2500. doi: 10.1007/s13197-021-05268-1. Epub 2021 Sep 23. 3: Haewpetch P, Rudeekulthamrong P, Kaulpiboon J. Enzymatic Synthesis of Maltitol and Its Inhibitory Effect on the Growth of Streptococcus mutans DMST 18777. Biomolecules. 2022 Jan 20;12(2):167. doi: 10.3390/biom12020167.
合成参考文献
参考文献:10.1155/2011/405139 摘要:Shimizu E, Kobayashi T, Wakabayashi H, Yamauchi K, Iwatsuki K, Yoshie H. Effects of Orally Administered Lactoferrin and Lactoperoxidase-Containing Tablets on Clinical and Bacteriological Profiles in Chronic Periodontitis Patients. International Journal of Dentistry. 2011;2011():1–9. doi: 10.1155/2011/405139.